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Links from GEO DataSets

Items: 9

1.

Expression data from the hippocampus of LPS induced depression mice model treated with Luteolin

(Submitter supplied) Gene expression profiling reveals a potential role of Luteolin in LPS induced depression model LPS depression induced mice were orally treated with luteolin (10 mg/kg body weight) once per day during 8 consecutive days. Microarray gene expression was conducted on mice hippocampal tissues. Two mice brains were used for each expermient . The Microarray gene expression was conducted on hipocampus from LPS depression induced mice model(LPS group), LPS depression induced mice model treated with luteolin(LPS+L group), Normal mice (PBS group) and Normal mice treated with luteolin (PBS+L).
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11180
16 Samples
Download data: CEL, CHP, XLSX
Series
Accession:
GSE181285
ID:
200181285
2.

Expression data from the Neural Stem Cells (NSCs) of LPS induced depression mice model treated with Luteolin

(Submitter supplied) Gene expression profiling reveals a potential role of Luteolin in LPS induced depression model LPS depression induced mice were orally treated with luteolin (10 mg/kg body weight) once per day during 8 consecutive days. Microarray gene expression was conducted for isolated mice Neural Stem Cells (NSCs) . Two mice brain were used for each expermient. The Microarray gene expression was conducted on NSCs and hipocampus from LPS depression induced depression mice (LPS group), LPS depression induced depression mice treated with luteolin(LPS+L group), Normal mice (PBS group) and Normal mice treated with luteolin (PBS+L).
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11180
7 Samples
Download data: CEL, CHP, XLS
Series
Accession:
GSE181522
ID:
200181522
3.

Expression data from Luteolin-treated human Neural Stem Cells (hNSCs)

(Submitter supplied) Gene expression profiling reveals a potential role of Luteolin in human neuronal stem cells (hNSCs) differentiation . hNSCs purchased from Gibco were treated with 1 μM verbenalin for 24 hours. Microarray gene expression profiling was conducted for biological replicates of hNSCs cultured in differentiation cell culture medium supplemented with Luteolin for 24 hours and untreated control cells cultured in differentiation cell cultured medium .
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13667
6 Samples
Download data: CEL, CHP
Series
Accession:
GSE148160
ID:
200148160
4.

Luteolin has anti-inflammatory and neurotrophic effects on microglia

(Submitter supplied) Our aim was to identify genes that were differentially expressed in microglia stimulated with Lipopolysaccharide, Luteolin, or both. Affymetrix microarrays were used to analyze RNA samples
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3613
Platform:
GPL1261
12 Samples
Download data: CEL
Series
Accession:
GSE18740
ID:
200018740
5.
Full record GDS3613

Luteolin effect on pro-inflammatory challenged microglial cell line

Analysis of lipopolysaccharide-activated microglial BV-2 cells treated with luteolin, a plant derived flavonoid. Luteolin possesses the ability to scavenge oxygen and nitrogen species, and exhibits anti-inflammatory activities. Results provide insight into the immuno-modulatory effects of luteolin.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 agent sets
Platform:
GPL1261
Series:
GSE18740
12 Samples
Download data: CEL
6.

Gene expression profile at single cell level of human neural stem cells (hNSCs) at 35degC and 37degC treatment.

(Submitter supplied) In order to elucidate why mild hypothermia of 35degC could promote neurogenesis of cultured hNSCs, we performed single-cell RNA sequencing (scRNA-seq) to reveal the molecular mechanism.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
2 Samples
Download data: MTX, TSV
Series
Accession:
GSE241889
ID:
200241889
7.

MRNAs bound to RBM3 of hNSCs under differentiation conditions at 35℃ and 37℃.

(Submitter supplied) To isolate RNA molecules bound to RBM3, we performed CLIP-seq analysis using differentiated hNSCs cultured in neural differentiation medium at 35℃ and 37℃.
Organism:
Homo sapiens
Type:
Other
Platform:
GPL24676
2 Samples
Download data: TXT
Series
Accession:
GSE241548
ID:
200241548
8.

Expression profiles in HMGN1-overexpressed neural precursor cells

(Submitter supplied) Neural precursor cells (NPCs) are multipotent cells that can generate neurons, astrocytes, and oligodendrocytes in the mammalian central nervous system. Although high mobility group nucleosomal binding domain 1 (HMGN1) was highly expressed in NPCs, its functions in neural development are not fully understood. We performed microarray analysis to examine changes in gene expression between control and HMGN1-overexpressed NPCs.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
2 Samples
Download data: CEL
Series
Accession:
GSE57534
ID:
200057534
9.

Effect of radiation exposure on gene expression in neurospheres

(Submitter supplied) To investigate the radiotoxicity on Neural Progenitor Cells (NPC) in neuropsheres exposed to x-ray radiation
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32190
24 Samples
Download data: TXT
Series
Accession:
GSE242899
ID:
200242899
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