GEO DataSets

Analysis of yox1 yhp double mutants across two cell cycles, a length of 2 hours after synchronization with alpha factor. Results compared to those from an experiment using wild type cells (GDS2347) and provide insight into the role of Yox1 and Yhp1 in early cell cycle box-dependent transcription.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, log10 ratio, 13 time sets

Platform:

GPL1914

Series:

GSE5283

13 Samples

Download data: GPR

(Submitter supplied) Two homeodomain proteins, Yox1 and Yhp1, act as repressors at early cell cycle boxes (ECBs) to restrict their activity to the M/G1 phase of the cell cycle in budding yeast. These proteins bind to Mcm1 and to a typical homeodomain binding site. The expression of Yox1 is periodic and directly correlated with its binding to, and repression of, ECB activity. The absence of Yox1 and Yhp1 or the constitutive expression of Yox1 leads to the loss of cell-cycle regulation of ECB activity. more...

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Dataset:

GDS2318

Platform:

GPL1914

13 Samples

Download data: GPR

(Submitter supplied) Yeast cell cycle microarray to identify global trancription profile. Keywords: cell cycle time course

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Dataset:

GDS2347

Platform:

GPL1914

13 Samples

Download data: GPR

Analysis of wild type W303 cells across two cell cycles, a length of 2 hours after synchronization with alpha factor. Results compared to those from an experiment using a yox1 yhp1 double mutant strain (GDS2318).

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, log ratio, 13 time sets

Platform:

GPL1914

Series:

GSE3635

13 Samples

Download data: GPR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25927

96 Samples

Download data

(Submitter supplied) We report gene expression data for strains that overexpress the transcriptional repressors Yox1 or Yhp1 from a synthetic, estradiol-inducible promoter. Gene expression was also measured in strains that overexpress unphosphorylatable alleles of either Yox1 or Yhp1, to determine whether blocking phosphorylation of these proteins by Cdk1 changes the spectrum of regulated genes. Finally, gene expression was measured in corresponding control strains in which Yox1/Yhp1 proteins were expressed from their endogenous promoters. more...

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25927

72 Samples

Download data: XLSX

(Submitter supplied) We report gene expression data for yeast strains expressing mutated versions of the transcriptional repressors Yox1 and Yhp1 that can't be phosphorylated by Cdk1. For comparision, gene expression was also measured in cells with deletions in one or both repressors. Genes that are downregulatd in phosphomutant strains and upregulated in deletion strains are likely to be target genes of these transcriptional repressors.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25927

24 Samples

Download data: CSV

(Submitter supplied) Analysis of gene expression across the cell cycle from wild type cells, and cells expressing alleles of Yox1, Yhp1, Hcm1, and Tos4 that cannot be phosphorylated by Cdk1. Expression of S-phase and M/G1 transcripts are downregulated when phosphorylation of these factors is blocked, demonstrating that Cdk1 promotes expression of late cell cycle genes.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL16244

32 Samples

Download data: TXT

(Submitter supplied) Transcription profiles across the yeast cell cycle. W303a cells were arrested with alpha factor in YEPD media. After release from arrest cells were sampled every 5 min for 2 hr. Keywords: cell cycle

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Dataset:

GDS2350

Platform:

GPL1914

50 Samples

Download data: GPR

Analysis of wild type W303a cells across two cell cycles, a length of 2 hours after synchronization with alpha factor. Gene expression examined at 5-minute intervals.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, log ratio, 25 time sets

Platform:

GPL1914

Series:

GSE4987

50 Samples

Download data: GPR