GEO DataSets

Analysis of liver from obesity-prone (OP) Wistar males with nonalcoholic fatty liver disease (NAFLD) induced by a 16 week, high-fat diet (HFD). Obesity-resistant (OR) males, fed an identical diet, were also examined. Results provide insight into molecular mechanisms underlying NAFLD pathogenesis.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, log ratio, 2 disease state sets

Platform:

GPL4294

Series:

GSE11492

8 Samples

Download data: TXT

(Submitter supplied) Rodents respond to chronic high fat diet in at least two ways: some of them may readily gain body weight and become obese (termed obesity-prone), and others may not (termed obesity-resistant). An integrated approach of transcript and metabolic profiling of obesity-prone and obesity-resistant rats has been conducted, showing significantly different transcript and metabolic profiles in the two phenotypes. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS3677

Platform:

GPL4294

8 Samples

Download data: TXT

(Submitter supplied) Nonalcoholic fatty liver disease (NAFLD) is a common disorder characterized by excessive hepatic fat accumulation, and potentially resulting in non-alcoholic steatohepatitis (NASH), liver cirrhosis (LC) and end-stage liver disease We used Rat Genome 230 2.0 microarray to further highlight the rat liver tissues after high-fat emulsion feeding.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL1355

12 Samples

Download data: CEL, CHP, XLS

(Submitter supplied) A high phosphorus (HP) diet causes disorders of renal function, bone metabolism, and vascular function. We previously demonstrated that DNA microarray analysis is an appropriate method to comprehensively evaluate the effects of a HP diet on kidney dysfunction such as calcification, fibrillization, and inflammation. We reported that type IIb sodium-dependent phosphate transporter is significantly up-regulated in this context. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL1355

8 Samples

Download data: CEL

(Submitter supplied) To investigate the effects of quality of fat in a high fat diet (HFD) over time on hepatic lipid storage and transcriptome in mice. In this dataset, we include the expression data obtained from dissected mouse liver after being fed with Control, HFD-EPA/DHA and HFD-corn oil diet for 8 and 12 weeks.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL16570

24 Samples

Download data: CEL

(Submitter supplied) High-protein diets are known to reduce adiposity in the context of high carbohydrate and Western diets. However, few studies have investigated the specific high-protein effect on lipogenesis induced by a high-sucrose (HS) diet or fat deposition induced by high-fat feeding. We aimed to determine the effects of high protein intake on the development of fat deposition and partitioning in response to high-fat and/or HS feeding. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL6247

6 Samples

Download data: CEL, PDF

(Submitter supplied) Analysis of tissues of DBA/2 mice fed a standard breeding diet (SBD) and high fat diet (HFD) revealed tissue specific roles in inflammation and disease, and altered communication between tissues. The tissues surveyed incuded adipose tissues (brown, inguinal, mesenteric, retro-peritoneal, subcutaneious and gonadal), muscle and liver.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6105

96 Samples

Download data: TXT

(Submitter supplied) A time course of orotic acid induced fatty liver disease. Kyoto and Wistar strain rats were exposed to orotic acid for days 1, 3 and 14. Controls are also included. Keywords = Wistar Keywords = Kyoto Keywords = orotic acid Keywords: time-course

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS765

Platform:

GPL85

14 Samples

Download data

Expression profiling of livers from inbred Kyotos and outbred Wistars fed a diet with 1% orotic acid to induce fatty liver disease. Profiles examined at various time points up to 14 days. Results used together with NMR spectroscopic analysis of the liver to identify perturbed metabolic pathways.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 2 strain, 4 time sets

Platform:

GPL85

Series:

GSE665

18 Samples

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