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Items: 1 to 20 of 132

1.
Full record GDS5618

Pregnancy effect on transplanted male pancreatic islets

Analysis of male donor islets transplanted into streptozotocin-induced diabetic females then removed at pregnancy day 12.5. During pregnancy, the mother’s insulin demand increases to sustain fetal growth. Results provide insight into the molecular response of male beta cells during pregnancy.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 gender, 4 protocol, 2 tissue sets
Platform:
GPL6246
Series:
GSE59143
20 Samples
Download data: CEL
2.
Full record GDS5430

Ethanol effect on lymphoblastoid cell lines from alcoholics

Analysis of lymphoblastoid cell lines (LCLs), obtained from alcoholics, after treatment with ethanol in vitro. Results provide insight into the feasibility of using LCLs to study the molecular consequences of exposure to alcohol.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 2 disease state, 2 gender, 42 individual sets
Platform:
GPL570
Series:
GSE52553
84 Samples
Download data: CEL, CHP
3.
Full record GDS5037

Severe asthma: bronchial epithelial cell

Analysis of bronchial epithelial cells from patients with severe asthma. Results provide insight into the molecular mechanisms underlying the development of severe asthma.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 disease state, 2 gender sets
Platform:
GPL6480
Series:
GSE43696
108 Samples
Download data: TXT
4.
Full record GDS5204

Age effect on normal adult brain: frontal cortical region

Analysis of postmortem neuropathologically normal brain samples from the frontal cortical regions of young, middle aged, normal aged and extremely aged adults. Results provide insight into molecular mechanisms of aging in frontal cortical regions of the brain.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 age, 2 gender sets
Platform:
GPL570
Series:
GSE53890
41 Samples
Download data: CEL
5.
Full record GDS5025

Age and gender effect on brain

Analysis of brain from young (7.5-8.5 months) and old (31-36 months) wildtype males and females. Brains are sexually dimorphic in adults. Results provide insight into the molecular mechanisms associated with brain aging across gender.
Organism:
Danio rerio
Type:
Expression profiling by array, transformed count, 2 age, 2 gender sets
Platform:
GPL1319
Series:
GSE53430
12 Samples
Download data: CEL
6.
Full record GDS5300

Restless Legs Syndrome model: embryonic forebrain

Analysis of forebrain from male and female E12.5 embryos heterozygous for the Meis1tm1Mtor allele. These animals express only one functional allele of Meis1, modeling the reduced expression of MEIS1 in Restless Legs Syndrome (RLS) patients. Results provide insight the role of MEIS1 in RLS.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 gender, 3 genotype/variation sets
Platform:
GPL6885
Series:
GSE44592
16 Samples
Download data
7.
Full record GDS5071

Non-syndromic cleft lip and palate: dental pulp stem cell cultures

Analysis of NSCL/P dental pulp stem cells cultures. This cell source consists of mesodermal and neural crest derived cells and, therefore, it shares the same origin with cells involved in lip and palate morphogenesis. Results provide insight into molecular mechanisms underlying NSCL/P etiology.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 2 gender sets
Platform:
GPL6244
Series:
GSE42589
13 Samples
Download data: CEL
8.
Full record GDS4869

Imatinib mesylate effect on bone marrow hematopoietic cells of chronic myeloid leukemia patients

Analysis of bone marrow hematopoietic cells in chronic myeloid leukemia (CML) patients one month after imatinib mesylate (IM) therapy. CML is caused by expression of the BCR/ABL fusion oncogene. Results provide insight into the molecular consequences of IM blockade of oncoprotein Bcr-Abl in CML.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 10 age, 10 gender, 10 individual, 3 protocol sets
Platform:
GPL570
Series:
GSE33075
27 Samples
Download data: CEL
DataSet
Accession:
GDS4869
ID:
4869
9.
Full record GDS4944

Estrogen effect on male and female haematopoietic stem cells

Comparison of male and female haematopoietic stem cells (HSCs) treated with estrogen. Results provide insight into the differences between the molecular response of male and female HSCs to sex hormones.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 gender sets
Platform:
GPL6246
Series:
GSE52711
12 Samples
Download data: CEL
10.
Full record GDS4774

Maternal western-style high fat diet effect on liver of two-week-old offspring

Analysis of livers from PD14 offspring of C57BL/6 dams fed a Western-style high fat/high cholesterol diet (WSD). Maternal diet is associated with the development of metabolism-related diseases in offspring. Results provide insight into molecular impact of maternal WSD on male and female offspring.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 gender, 2 protocol sets
Platform:
GPL11533
Series:
GSE46359
27 Samples
Download data: CEL
11.
Full record GDS5000

Mechanistic Indicators of Asthma (MICA) cohort: peripheral blood

Analysis of peripheral blood from asthmatic and non-asthmatic children (ages 9 to 13), participants of the MICA study conducted by the EPA from 11/2006 to 01/2007 in Detroit, MI. These results, together with clinical biomarker measurements, may help to differentiate asthmatics from non-asthmatics.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 5 age, 3 disease state, 2 gender sets
Platform:
GPL570
Series:
GSE35571
131 Samples
Download data: CEL
12.
Full record GDS5052

Pristane-induced arthritis effect on AIRmax and AIRmin acute inflammation model: footpad

Analysis of footpad from animals with high (AIRmax) or low (AIRmin) acute inflammation following 2 injections of pristine at 60-day intervals. Arthritis development was examined twice weekly for 160 days. Results provide insight into molecular mechanisms distinguishing the AIRmax and AIRmin models.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 gender, 2 genotype/variation sets
Platform:
GPL6246
Series:
GSE51516
8 Samples
Download data: CEL
13.
Full record GDS5051

Pristane-induced arthritis effect on AIRmin low acute inflammation model: footpad

Analysis of footpad from outbred animals with low (AIRmin) acute inflammation following two injections of pristine at 60-day intervals. Arthritis development was examined twice weekly for 160 days. Results provide insight into molecular mechanisms underlying arthritis induction and progression.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 gender, 2 protocol sets
Platform:
GPL6246
Series:
GSE51516
8 Samples
Download data: CEL
14.
Full record GDS5050

Pristane-induced arthritis effect on AIRmax high acute inflammation model: footpad

Analysis of footpad from outbred animals with high (AIRmax) acute inflammation following two injections of pristine at 60-day intervals. Arthritis development was examined twice weekly for 160 days. Results provide insight into molecular mechanisms underlying arthritis induction and progression.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 gender, 2 protocol sets
Platform:
GPL6246
Series:
GSE51516
8 Samples
Download data: CEL
15.
Full record GDS5016

Male and female in vitro cultured placental cell types

Analysis of four cell types from the placentas of male or female fetuses: cytotrophoblasts, syncytiotrophoblasts, and arterial and venous endothelial cells. Results provide insight into sex-biased molecular mechanisms underlying functional differences in gestations from male and female fetuses.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 cell type, 2 gender sets
Platform:
GPL6244
Series:
GSE44368
32 Samples
Download data: CEL
16.
Full record GDS5001

Allergen inhalation challenge effect on peripheral blood of asthmatic early responders and dual responders

Analysis of blood collected from asthmatics immediately prior to, and two hours after, cat allergen challenge. Some asthmatics are early responders while others are dual (early plus late) responders. Results provide insight into the molecular mechanisms underlying early and dual asthmatic responses.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 10 age, 2 gender, 14 individual, 2 other, 2 protocol sets
Platform:
GPL6244
Series:
GSE40240
28 Samples
Download data: CEL
17.
Full record GDS4879

Chronic high-level alcohol consumption effect on brain: post-mortem hippocampus

Analysis of post-mortem hippocampus of chronic alcoholics (CAs). Chronic high-level alcohol consumption leads to decreased white matter and inhibition of neurogenesis. Results provide insight into molecular mechanisms that may play a role in the risk for alcoholism.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 2 gender sets
Platform:
GPL6244
Series:
GSE44456
39 Samples
Download data: CEL
18.
Full record GDS4925

Age-related hearing loss model: cochlea

Analysis of cochlea from old CBA females and males with mild or severe age-related hearing loss (presbycusis). The CBA strain it loses its hearing progressively over its lifetime. Results provide insight into the molecular mechanisms underlying presbycusis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 age, 4 disease state, 2 gender sets
Platform:
GPL339
Series:
GSE49543
41 Samples
Download data: CEL, CHP
19.
Full record GDS5363

Osteoarthritis: peripheral blood mononuclear cells

Analysis of peripheral blood mononuclear cells (PBMCs) from osteoarthritis (OA) patients. Patients participated in the Genetics osteoARthritis and Progression (GARP) study. Results provide insight into the feasibility of using gene expression profiling of PBMCs to detect the onset of OA.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 2 gender sets
Platform:
GPL6947
Series:
GSE48556
139 Samples
Download data
DataSet
Accession:
GDS5363
ID:
5363
20.
Full record GDS4758

Postmortem Alzheimer's disease brains: Hisayama study

Analysis of postmortem brain tissues (frontal cortex, temporal cortex, hippocampus) from male and female Hisayama residents pathologically diagnosed as having Alzheimer's disease (AD) or an AD-like disorder. Results provide insight into the molecular mechanisms underlying AD brain pathology.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 2 gender, 3 tissue sets
Platform:
GPL6244
Series:
GSE36980
79 Samples
Download data: CEL, CHP
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