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SYG1 Syg1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854764, updated on 9-Dec-2024

Summary

Official Symbol
SYG1
Official Full Name
Syg1p
Primary source
SGD:S000001309
Locus tag
YIL047C
See related
AllianceGenome:SGD:S000001309; FungiDB:YIL047C; VEuPathDB:YIL047C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable inositol hexakisphosphate binding activity and phosphate transmembrane transporter activity. Involved in signal transduction. Located in plasma membrane. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human XPR1 (xenotropic and polytropic retrovirus receptor 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See SYG1 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (265115..267823, complement)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene putative polyprenol reductase Neighboring gene putative aminophospholipid-translocating P4-type ATPase NEO1 Neighboring gene uncharacterized protein Neighboring gene ubiquitin-binding SDF ubiquitin ligase complex subunit MET30

Interactions

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables inositol hexakisphosphate binding  
enables molecular_function  
enables phosphate transmembrane transporter activity  
Process Evidence Code Pubs
involved_in cellular response to phosphate starvation  
involved_in phosphate ion transport  
involved_in signal transduction PubMed 
Component Evidence Code Pubs
located_in fungal-type vacuole membrane PubMed 
located_in membrane  
located_in mitochondrion PubMed 
is_active_in plasma membrane  
located_in plasma membrane PubMed 
located_in plasma membrane  

General protein information

Preferred Names
Syg1p
NP_012217.3
  • Plasma membrane hypothetical protein; targeted to vacuole via AP-3 pathway; truncation and overexpression suppresses lethality of G-alpha protein deficiency

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    265115..267823 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179397.3 → NP_012217.3  TPA: Syg1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012217.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVN4, P40528, P40964
    UniProtKB/TrEMBL
    A6ZVM2
    Conserved Domains (2) summary
    COG5408
    Location:1 → 310
    COG5408; SPX domain-containing protein [Signal transduction mechanisms]
    COG5409
    Location:402 → 803
    COG5409; EXS domain-containing protein [Signal transduction mechanisms]
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