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    ENA1 Na(+)/Li(+)-exporting P-type ATPase ENA1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851610, updated on 9-Dec-2024

    Summary

    Official Symbol
    ENA1
    Official Full Name
    Na(+)/Li(+)-exporting P-type ATPase ENA1
    Primary source
    SGD:S000002447
    Locus tag
    YDR040C
    See related
    AllianceGenome:SGD:S000002447; FungiDB:YDR040C; VEuPathDB:YDR040C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    HOR6; PMR2
    Summary
    Enables P-type potassium transmembrane transporter activity and P-type sodium transporter activity. Involved in several processes, including cellular response to glucose starvation; hyperosmotic response; and metal ion transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ENA1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (535192..538467, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene putative Na(+)-exporting P-type ATPase ENA5 Neighboring gene Na(+)-exporting P-type ATPase ENA2 Neighboring gene mitochondrial 37S ribosomal protein RSM10 Neighboring gene uncharacterized protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ABC-type sodium transporter activity  
    enables ATP binding  
    enables ATP hydrolysis activity  
    enables ATPase-coupled monoatomic cation transmembrane transporter activity  
    enables P-type ion transporter activity  
    enables P-type potassium transmembrane transporter activity  
    enables P-type potassium transmembrane transporter activity PubMed 
    enables P-type sodium transporter activity  
    enables P-type sodium transporter activity PubMed 
    enables P-type sodium transporter activity  
    enables P-type sodium transporter activity PubMed 
    enables metal ion binding  
    enables metal ion transmembrane transporter activity  
    Process Evidence Code Pubs
    involved_in cellular response to glucose starvation PubMed 
    involved_in hyperosmotic response PubMed 
    involved_in inorganic cation transmembrane transport  
    involved_in intracellular calcium ion homeostasis  
    involved_in monoatomic cation transmembrane transport  
    involved_in monoatomic cation transport  
    involved_in monoatomic ion transmembrane transport  
    involved_in potassium ion transmembrane transport  
    involved_in potassium ion transport  
    involved_in potassium ion transport  
    involved_in potassium ion transport PubMed 
    involved_in response to pH PubMed 
    involved_in response to salt stress PubMed 
    involved_in sodium ion transmembrane transport  
    involved_in sodium ion transport  
    involved_in sodium ion transport  
    involved_in sodium ion transport PubMed 
    involved_in transmembrane transport PubMed 
    involved_in transmembrane transport PubMed 
    Component Evidence Code Pubs
    located_in cell periphery PubMed 
    located_in fungal-type vacuole PubMed 
    located_in membrane  
    located_in plasma membrane PubMed 
    is_active_in plasma membrane  
    located_in plasma membrane PubMed 
    located_in plasma membrane  

    General protein information

    Preferred Names
    Na(+)/Li(+)-exporting P-type ATPase ENA1
    NP_010325.1
    • P-type ATPase sodium pump; involved in Na+ and Li+ efflux to allow salt tolerance

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      535192..538467 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180348.1 → NP_010325.1  TPA: Na(+)/Li(+)-exporting P-type ATPase ENA1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010325.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VS28, P13587
      UniProtKB/TrEMBL
      A6ZY07
      Conserved Domains (1) summary
      TIGR01523
      Location:11 → 1055
      ATPase-IID_K-Na; potassium and/or sodium efflux P-type ATPase, fungal-type
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