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    QCR8 ubiquinol--cytochrome-c reductase subunit 8 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853273, updated on 9-Dec-2024

    Summary

    Official Symbol
    QCR8
    Official Full Name
    ubiquinol--cytochrome-c reductase subunit 8
    Primary source
    SGD:S000003702
    Locus tag
    YJL166W
    See related
    AllianceGenome:SGD:S000003702; FungiDB:YJL166W; VEuPathDB:YJL166W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    COR5
    Summary
    Enables ubiquinol-cytochrome-c reductase activity. Involved in mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion. Part of respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 4. Orthologous to human UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See QCR8 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (106434..106718)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene histone methyltransferase SET2 Neighboring gene bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase Neighboring gene protein kinase HAL5 Neighboring gene cAMP-dependent protein kinase catalytic subunit TPK1

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Component Evidence Code Pubs
    located_in mitochondrial inner membrane  
    located_in mitochondrion PubMed 
    located_in mitochondrion  
    part_of respiratory chain complex III  
    part_of respiratory chain complex III PubMed 
    part_of respiratory chain complex III  

    General protein information

    Preferred Names
    ubiquinol--cytochrome-c reductase subunit 8
    NP_012369.1
    • Subunit 8 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      106434..106718
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181599.1 → NP_012369.1  TPA: ubiquinol--cytochrome-c reductase subunit 8 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012369.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VW21, P08525
      UniProtKB/TrEMBL
      A6ZQG6, B3LPV7, C7GRZ4, C8ZB53, G2WGK7, N1P3U7
      Conserved Domains (1) summary
      pfam02939
      Location:12 → 89
      UcrQ; UcrQ family
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