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    ind intermediate neuroblasts defective [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 2768974, updated on 9-Dec-2024

    Summary

    Official Symbol
    indprovided by FlyBase
    Official Full Name
    intermediate neuroblasts defectiveprovided by FlyBase
    Primary source
    FLYBASE:FBgn0025776
    Locus tag
    Dmel_CG11551
    See related
    AllianceGenome:FB:FBgn0025776
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11551; Dmel\CG11551; Ind; ind/Gsx
    Summary
    Enables DNA-binding transcription factor activity; DNA-binding transcription factor binding activity; and sequence-specific DNA binding activity. Involved in central nervous system development; negative regulation of gene expression; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including anlage in statu nascendi; central brain anlage; embryonic procephalic segment; ganglia; and neuroblasts. Orthologous to human GSX2 (GS homeobox 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ind in Genome Data Viewer
    Location:
    71B2-71B2; 3-42 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15042799..15043924, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15035899..15037024, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Synaptotagmin beta Neighboring gene uncharacterized protein Neighboring gene Regulatory particle non-ATPase 12-related Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in brain development  
    involved_in brain development PubMed 
    involved_in central nervous system development  
    involved_in central nervous system development PubMed 
    involved_in central nervous system development PubMed 
    involved_in dorsal/ventral pattern formation PubMed 
    involved_in ectoderm development PubMed 
    involved_in negative regulation of gene expression PubMed 
    involved_in negative regulation of transcription by RNA polymerase II PubMed 
    involved_in neuron differentiation  
    involved_in pattern specification process PubMed 
    involved_in regulation of DNA-templated transcription  
    involved_in regulation of transcription by RNA polymerase II  
    involved_in regulation of transcription by RNA polymerase II PubMed 
    involved_in ventral cord development PubMed 
    involved_in ventral cord development PubMed 
    involved_in ventral cord development PubMed 
    Component Evidence Code Pubs
    is_active_in nucleus  
    located_in nucleus PubMed 

    General protein information

    Preferred Names
    intermediate neuroblasts defective
    Names
    CG11551-PB
    ind-PB
    intermediate nerve cord defective
    intermediate neuroblast defective

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15042799..15043924 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206365.3 → NP_996087.2  intermediate neuroblasts defective [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996087.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O96620, Q7KUL4
      Conserved Domains (1) summary
      pfam00046
      Location:231 → 283
      Homeobox; Homeobox domain
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