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    CG15117 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37197, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG15117provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034417
    Locus tag
    Dmel_CG15117
    See related
    AllianceGenome:FB:FBgn0034417
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15117
    Summary
    Predicted to enable beta-glucuronidase activity and carbohydrate binding activity. Involved in sexual reproduction. Located in extracellular space. Is expressed in several structures, including adult head; adult heart; embryonic/larval fat body; embryonic/larval midgut; and extraembryonic structure. Human ortholog(s) of this gene implicated in Sly syndrome. Orthologous to human GUSB (glucuronidase beta). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See CG15117 in Genome Data Viewer
    Location:
    56B5-56B5; 2-88 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19122231..19129300, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15009736..15016805, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene 5-hydroxytryptamine (serotonin) receptor 1A Neighboring gene Ionotropic receptor 56a Neighboring gene brother of tout-velu Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables beta-glucuronidase activity  
    enables beta-glucuronidase activity PubMed 
    enables carbohydrate binding  
    enables hydrolase activity, hydrolyzing O-glycosyl compounds  
    Component Evidence Code Pubs
    located_in extracellular space PubMed 
    is_active_in extracellular space  

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG15117-PA
    CG15117-PB
    CG15117-PC
    CG15117-PD
    CG15117-PE
    CG15117-PF
    NP_001014535.1
    NP_001286599.1
    NP_001286600.1
    NP_001286601.1
    NP_611395.1
    NP_725851.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19122231..19129300 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137551.3 → NP_611395.1  uncharacterized protein Dmel_CG15117, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611395.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C8VV29, Q7K173
      Related
      FBpp0085777
      Conserved Domains (4) summary
      PRK10150
      Location:34 → 634
      PRK10150; beta-D-glucuronidase; Provisional
      pfam00703
      Location:224 → 334
      Glyco_hydro_2; Glycosyl hydrolases family 2
      pfam02837
      Location:43 → 222
      Glyco_hydro_2_N; Glycosyl hydrolases family 2, sugar binding domain
      cl23725
      Location:342 → 631
      Glyco_hydro_1; Glycosyl hydrolase family 1
    2. NM_166324.2 → NP_725851.1  uncharacterized protein Dmel_CG15117, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725851.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBG9, Q6NL66
      Related
      FBpp0085778
      Conserved Domains (4) summary
      PRK10150
      Location:48 → 648
      PRK10150; beta-D-glucuronidase; Provisional
      pfam00703
      Location:238 → 348
      Glyco_hydro_2; Glycosyl hydrolases family 2
      pfam02837
      Location:57 → 236
      Glyco_hydro_2_N; Glycosyl hydrolases family 2, sugar binding domain
      cl23725
      Location:356 → 645
      Glyco_hydro_1; Glycosyl hydrolase family 1
    3. NM_001014535.2 → NP_001014535.1  uncharacterized protein Dmel_CG15117, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001014535.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBH0, C8VV29
      Conserved Domains (4) summary
      PRK10150
      Location:34 → 634
      PRK10150; beta-D-glucuronidase; Provisional
      pfam00703
      Location:224 → 334
      Glyco_hydro_2; Glycosyl hydrolases family 2
      pfam02837
      Location:43 → 222
      Glyco_hydro_2_N; Glycosyl hydrolases family 2, sugar binding domain
      cl23725
      Location:342 → 631
      Glyco_hydro_1; Glycosyl hydrolase family 1
    4. NM_001299670.1 → NP_001286599.1  uncharacterized protein Dmel_CG15117, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286599.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LGY4, C8VV29
      Conserved Domains (4) summary
      PRK10150
      Location:26 → 626
      PRK10150; beta-D-glucuronidase; Provisional
      pfam00703
      Location:216 → 326
      Glyco_hydro_2; Glycosyl hydrolases family 2
      pfam02837
      Location:35 → 214
      Glyco_hydro_2_N; Glycosyl hydrolases family 2, sugar binding domain
      cl23725
      Location:334 → 623
      Glyco_hydro_1; Glycosyl hydrolase family 1
    5. NM_001299672.1 → NP_001286601.1  uncharacterized protein Dmel_CG15117, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286601.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LFU6, C8VV29
      Conserved Domains (1) summary
      PRK10150
      Location:1 → 601
      PRK10150; beta-D-glucuronidase; Provisional
    6. NM_001299671.1 → NP_001286600.1  uncharacterized protein Dmel_CG15117, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286600.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LFU6, C8VV29
      Conserved Domains (1) summary
      PRK10150
      Location:1 → 601
      PRK10150; beta-D-glucuronidase; Provisional
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