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    Srrm1 serine/arginine repetitive matrix 1 [ Mus musculus (house mouse) ]

    Gene ID: 51796, updated on 9-Dec-2024

    Summary

    Official Symbol
    Srrm1provided by MGI
    Official Full Name
    serine/arginine repetitive matrix 1provided by MGI
    Primary source
    MGI:MGI:1858303
    See related
    Ensembl:ENSMUSG00000028809 AllianceGenome:MGI:1858303
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    POP101; Srm160
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to act upstream of or within mRNA splicing, via spliceosome. Part of spliceosomal complex. Is expressed in central nervous system; genitourinary system; pancreas epithelium; and sensory organ. Orthologous to human SRRM1 (serine and arginine repetitive matrix 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 32.0), CNS E11.5 (RPKM 29.1) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Srrm1 in Genome Data Viewer
    Location:
    4 D3; 4 67.34 cM
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (135047795..135080787, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (135320484..135353277, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_11711 Neighboring gene predicted gene, 30701 Neighboring gene STARR-positive B cell enhancer ABC_E10266 Neighboring gene predicted gene 12984 Neighboring gene STARR-positive B cell enhancer ABC_E6233 Neighboring gene noncompact myelin associated protein Neighboring gene regulator of calcineurin 3 Neighboring gene microRNA 700

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    NOT enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    serine/arginine repetitive matrix protein 1
    Names
    Ser/Arg-related nuclear matrix protein
    plenty-of-prolines-101

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130477.2NP_001123949.1  serine/arginine repetitive matrix protein 1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 5' coding region, compared to variant 1. The encoded protein (isoform 2) lacks 5 amino acids in the N-terminus, compared to isoform 1.
      Source sequence(s)
      AL627078, AL627185
      Consensus CDS
      CCDS51329.1
      UniProtKB/TrEMBL
      A2A8V9, E9QKA4
      Related
      ENSMUSP00000081906.6, ENSMUST00000084846.12
      Conserved Domains (2) summary
      pfam00906
      Location:621712
      Hepatitis_core; Hepatitis core antigen
      pfam01480
      Location:46115
      PWI; PWI domain
    2. NM_001369067.1NP_001355996.1  serine/arginine repetitive matrix protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL627078, AL627185
      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:623820
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    3. NM_001369068.1NP_001355997.1  serine/arginine repetitive matrix protein 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL627078, AL627185
      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:622819
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    4. NM_001369069.1NP_001355998.1  serine/arginine repetitive matrix protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL627078, AL627185
      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03247
      Location:611806
      PHA03247; large tegument protein UL36; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    5. NM_001369070.1NP_001355999.1  serine/arginine repetitive matrix protein 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL627078, AL627185
      Consensus CDS
      CCDS89844.1
      UniProtKB/TrEMBL
      A2A8V8, E9QKA4
      Related
      ENSMUSP00000101487.2, ENSMUST00000105861.8
      Conserved Domains (2) summary
      PHA03247
      Location:389805
      PHA03247; large tegument protein UL36; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    6. NM_001369071.1NP_001356000.1  serine/arginine repetitive matrix protein 1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL627078, AL627185
      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03247
      Location:389804
      PHA03247; large tegument protein UL36; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    7. NM_001369072.1NP_001356001.1  serine/arginine repetitive matrix protein 1 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL627078, AL627185
      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:594791
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    8. NM_001369073.1NP_001356002.1  serine/arginine repetitive matrix protein 1 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL627078, AL627185
      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03247
      Location:389775
      PHA03247; large tegument protein UL36; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    9. NM_001369074.1NP_001356003.1  serine/arginine repetitive matrix protein 1 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AL627078, AL627185
      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:511708
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:132
      PWI; PWI domain
    10. NM_016799.4NP_058079.2  serine/arginine repetitive matrix protein 1 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AL627078, AL627185
      Consensus CDS
      CCDS38919.2
      UniProtKB/TrEMBL
      E9PUK6, E9QKA4
      Related
      ENSMUSP00000125003.2, ENSMUST00000136342.9
      Conserved Domains (2) summary
      pfam00906
      Location:626717
      Hepatitis_core; Hepatitis core antigen
      pfam01480
      Location:46115
      PWI; PWI domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      135047795..135080787 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164230.1XP_036020123.1  serine/arginine repetitive matrix protein 1 isoform X8

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:589786
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    2. XM_030253660.2XP_030109520.1  serine/arginine repetitive matrix protein 1 isoform X7

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:593790
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    3. XM_030253661.2XP_030109521.1  serine/arginine repetitive matrix protein 1 isoform X9

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03247
      Location:359775
      PHA03247; large tegument protein UL36; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    4. XM_036164229.1XP_036020122.1  serine/arginine repetitive matrix protein 1 isoform X6

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:593790
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    5. XM_030253657.2XP_030109517.1  serine/arginine repetitive matrix protein 1 isoform X2

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:618815
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    6. XM_030253669.2XP_030109529.1  serine/arginine repetitive matrix protein 1 isoform X18

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03247
      Location:384799
      PHA03247; large tegument protein UL36; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    7. XM_030253659.2XP_030109519.1  serine/arginine repetitive matrix protein 1 isoform X5

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03247
      Location:384800
      PHA03247; large tegument protein UL36; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    8. XM_006539029.4XP_006539092.1  serine/arginine repetitive matrix protein 1 isoform X4

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:609809
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    9. XM_030253658.2XP_030109518.1  serine/arginine repetitive matrix protein 1 isoform X3

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:609806
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    10. XM_006539026.4XP_006539089.1  serine/arginine repetitive matrix protein 1 isoform X1

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:623820
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:46115
      PWI; PWI domain
    11. XM_030253664.2XP_030109524.1  serine/arginine repetitive matrix protein 1 isoform X13

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:536733
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:132
      PWI; PWI domain
    12. XM_006539033.4XP_006539096.1  serine/arginine repetitive matrix protein 1 isoform X10

      See identical proteins and their annotated locations for XP_006539096.1

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:541738
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:132
      PWI; PWI domain
    13. XM_030253667.2XP_030109527.1  serine/arginine repetitive matrix protein 1 isoform X17

      Conserved Domains (1) summary
      PHA03247
      Location:109347
      PHA03247; large tegument protein UL36; Provisional
    14. XM_030253665.2XP_030109525.1  serine/arginine repetitive matrix protein 1 isoform X15

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:510707
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:132
      PWI; PWI domain
    15. XM_036164232.1XP_036020125.1  serine/arginine repetitive matrix protein 1 isoform X16

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03247
      Location:276692
      PHA03247; large tegument protein UL36; Provisional
      pfam01480
      Location:132
      PWI; PWI domain
    16. XM_017320313.3XP_017175802.1  serine/arginine repetitive matrix protein 1 isoform X14

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:511708
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:132
      PWI; PWI domain
    17. XM_030253663.2XP_030109523.1  serine/arginine repetitive matrix protein 1 isoform X13

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:536733
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:132
      PWI; PWI domain
    18. XM_030253662.2XP_030109522.1  serine/arginine repetitive matrix protein 1 isoform X12

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:540737
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:132
      PWI; PWI domain
    19. XM_036164231.1XP_036020124.1  serine/arginine repetitive matrix protein 1 isoform X11

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:540737
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:132
      PWI; PWI domain
    20. XM_006539032.5XP_006539095.1  serine/arginine repetitive matrix protein 1 isoform X10

      See identical proteins and their annotated locations for XP_006539095.1

      UniProtKB/TrEMBL
      E9QKA4
      Conserved Domains (2) summary
      PHA03307
      Location:541738
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01480
      Location:132
      PWI; PWI domain
    21. XM_030253666.2XP_030109526.1  serine/arginine repetitive matrix protein 1 isoform X17

      Conserved Domains (1) summary
      PHA03247
      Location:109347
      PHA03247; large tegument protein UL36; Provisional
    22. XM_030253668.2XP_030109528.1  serine/arginine repetitive matrix protein 1 isoform X17

      Conserved Domains (1) summary
      PHA03247
      Location:109347
      PHA03247; large tegument protein UL36; Provisional

    RNA

    1. XR_004941933.1 RNA Sequence

    2. XR_004941932.1 RNA Sequence

    3. XR_003954981.2 RNA Sequence

    4. XR_004941935.1 RNA Sequence

    5. XR_004941934.1 RNA Sequence