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    Vps52 Vacuolar protein sorting 52 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33774, updated on 9-Dec-2024

    Summary

    Official Symbol
    Vps52provided by FlyBase
    Official Full Name
    Vacuolar protein sorting 52provided by FlyBase
    Primary source
    FLYBASE:FBgn0031710
    Locus tag
    Dmel_CG7371
    See related
    AllianceGenome:FB:FBgn0031710
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7371; Dmel\CG7371
    Summary
    Enables small GTPase binding activity. Involved in endocytic recycling. Located in trans-Golgi network. Part of GARP complex. Is expressed in organism. Orthologous to human VPS52 (VPS52 subunit of GARP complex). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Vps52 in Genome Data Viewer
    Location:
    25E5-25E5; 2-17 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5521281..5523898, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5521281..5523898, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45287 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44793 Neighboring gene clot Neighboring gene Elongator complex protein 4 Neighboring gene Chromosome associated protein D3 Neighboring gene Cytochrome c oxidase copper chaperone COX11

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables small GTPase binding PubMed 
    enables syntaxin binding  
    enables syntaxin binding  
    Process Evidence Code Pubs
    involved_in Golgi to vacuole transport  
    involved_in endocytic recycling  
    involved_in endocytic recycling PubMed 
    involved_in endocytic recycling  
    involved_in lysosomal transport  
    involved_in retrograde transport, endosome to Golgi  
    Component Evidence Code Pubs
    part_of GARP complex  
    part_of GARP complex PubMed 
    located_in Golgi apparatus  
    located_in recycling endosome  
    located_in trans-Golgi network PubMed 

    General protein information

    Preferred Names
    vacuolar protein sorting 52
    Names
    CG7371-PA
    Vps52-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5521281..5523898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135087.3 → NP_608931.1  vacuolar protein sorting 52 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608931.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86NL4, Q9VMQ8
      Related
      FBpp0078760
      Conserved Domains (1) summary
      pfam04129
      Location:42 → 546
      Vps52; Vps52 / Sac2 family
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