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    f-cup flyers-cup [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41677, updated on 9-Dec-2024

    Summary

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    Official Symbol
    f-cupprovided by FlyBase
    Official Full Name
    flyers-cupprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028487
    Locus tag
    Dmel_CG9611
    See related
    AllianceGenome:FB:FBgn0028487
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH09045; CG9611; Dmel\CG9611
    Summary
    Predicted to be involved in intracellular signal transduction. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut; embryonic/larval midgut primordium; ganglia; and male germline cell. Orthologous to human LRRC40 (leucine rich repeat containing 40). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See f-cup in Genome Data Viewer
    Location:
    87F11-87F11; 3-54 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13695263..13700838, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9520985..9526560, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Lkb1 kinase Neighboring gene oocyte maintenance defects Neighboring gene falafel Neighboring gene uncharacterized protein Neighboring gene neither inactivation nor afterpotential B Neighboring gene Adenosine deaminase-related growth factor D Neighboring gene Adenosine deaminase-related growth factor C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The CPEB protein Orb2 has multiple functions during spermatogenesis in Drosophila melanogaster. Xu S, et al. PLoS Genet, 2012. PMID 23209437, Free PMC Article
    2. Antagonistic pleiotropy for life-history traits at the gene expression level. Bochdanovits Z, et al. Proc Biol Sci, 2004 Feb 7. PMID 15101424, Free PMC Article
    3. Post-meiotic transcription in Drosophila testes. Barreau C, et al. Development, 2008 Jun. PMID 18434411
    4. Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. Slack C, et al. PLoS Genet, 2010 Mar 19. PMID 20333234, Free PMC Article
    5. Spatially revealed roles for lncRNAs in Drosophila spermatogenesis, Y chromosome function and evolution. Shao Z, et al. Nat Commun, 2024 May 7. PMID 38714658, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    flyers-cup
    Names
    CG9611-PA
    CG9611-PB
    CG9611-PC
    CG9611-PD
    CG9611-PE
    CG9611-PF
    CG9611-PG
    CG9611-PH
    CG9611-PI
    f-cup-PA
    f-cup-PB
    f-cup-PC
    f-cup-PD
    f-cup-PE
    f-cup-PF
    f-cup-PG
    f-cup-PH
    f-cup-PI
    gp150-like

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      13695263..13700838 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001104303.2 → NP_001097773.1  flyers-cup, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097773.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JQZ8, Q29QD5
      Conserved Domains (3) summary
      cd00116
      Location:34 → 256
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:37 → 59
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:59 → 114
      LRR_8; Leucine rich repeat

    2. NM_169550.2 → NP_731852.2  flyers-cup, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731852.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86NW5, Q9V3X1
      Related
      FBpp0082311
      Conserved Domains (3) summary
      cd00116
      Location:155 → 377
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:158 → 180
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:180 → 235
      LRR_8; Leucine rich repeat

    3. NM_001275615.1 → NP_001262544.1  flyers-cup, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262544.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KG03
      Conserved Domains (3) summary
      cd00116
      Location:155 → 377
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:158 → 180
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:180 → 235
      LRR_8; Leucine rich repeat

    4. NM_001104302.2 → NP_001097772.1  flyers-cup, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097772.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29QD5, Q6NLJ7
      Conserved Domains (3) summary
      cd00116
      Location:82 → 304
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:85 → 107
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:107 → 162
      LRR_8; Leucine rich repeat

    5. NM_142049.3 → NP_650306.1  flyers-cup, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650306.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KSK8, Q86NW5
      Related
      FBpp0082312
      Conserved Domains (3) summary
      cd00116
      Location:112 → 334
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:115 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:137 → 192
      LRR_8; Leucine rich repeat

    6. NM_001275617.1 → NP_001262546.1  flyers-cup, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262546.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGK9, Q29QD5
      Conserved Domains (3) summary
      cd00116
      Location:112 → 334
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:115 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:137 → 192
      LRR_8; Leucine rich repeat

    7. NM_001275616.1 → NP_001262545.1  flyers-cup, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262545.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFW1
      Conserved Domains (3) summary
      cd00116
      Location:112 → 334
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:115 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:137 → 192
      LRR_8; Leucine rich repeat

    8. NM_001275618.1 → NP_001262547.1  flyers-cup, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262547.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29QD5, Q6NLJ7
      Conserved Domains (3) summary
      cd00116
      Location:82 → 304
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:85 → 107
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:107 → 162
      LRR_8; Leucine rich repeat

    9. NM_001104304.2 → NP_001097774.1  flyers-cup, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097774.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JQZ7, Q86NW5
      Conserved Domains (3) summary
      cd00116
      Location:82 → 304
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:85 → 107
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:107 → 162
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFW1 A0A0B4KFW1
    A0A0B4KG03 A0A0B4KG03
    A0A0B4KGK9 A0A0B4KGK9
    A8JQZ7 A8JQZ7
    A8JQZ8 A8JQZ8
    Q6NLJ7 Q6NLJ7
    Q7KSK8 Q7KSK8
    Q86NW5 Q86NW5
    Q9V3X1 Q9V3X1

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