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    USA1 Usa1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854979, updated on 9-Dec-2024

    Summary

    Official Symbol
    USA1
    Official Full Name
    Usa1p
    Primary source
    SGD:S000004491
    Locus tag
    YML029W
    See related
    AllianceGenome:SGD:S000004491; FungiDB:YML029W; VEuPathDB:YML029W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables molecular adaptor activity. Involved in ERAD pathway; mRNA splicing, via spliceosome; and positive regulation of protein autoubiquitination. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See USA1 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (217362..219878)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Ndc1p Neighboring gene Rcf1p Neighboring gene thioredoxin peroxidase TSA1 Neighboring gene Yox1p

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Component Evidence Code Pubs
    located_in endoplasmic reticulum PubMed 
    located_in endoplasmic reticulum  
    located_in endoplasmic reticulum membrane  
    located_in endoplasmic reticulum membrane PubMed 
    located_in membrane  

    General protein information

    Preferred Names
    Usa1p
    NP_013683.1
    • Scaffold subunit of the Hrd1p ubiquitin ligase; also promotes ligase oligomerization; involved in ER-associated protein degradation (ERAD); interacts with the U1 snRNP-specific protein, Snp1p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      217362..219878
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182387.1 → NP_013683.1  TPA: Usa1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013683.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZE5, Q03714
      UniProtKB/TrEMBL
      B3LLM3, B5VP97, C8ZEH5
      Conserved Domains (1) summary
      cl28922
      Location:276 → 341
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
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