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    Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 [ Mus musculus (house mouse) ]

    Gene ID: 230861, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Eif4g3provided by MGI
    Official Full Name
    eukaryotic translation initiation factor 4 gamma, 3provided by MGI
    Primary source
    MGI:MGI:1923935
    See related
    Ensembl:ENSMUSG00000028760 AllianceGenome:MGI:1923935
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    repro8; Gm32394; eIF4GII; G1-419-52; 1500002J22Rik; 4930523M17Rik
    Summary
    Enables translation initiation factor activity. Involved in positive regulation of translation and spermatid development. Acts upstream of or within positive regulation of meiosis I; positive regulation of protein phosphorylation; and spermatogenesis. Is active in intracellular non-membrane-bounded organelle and synapse. Is expressed in nervous system; neural retina; and submandibular gland primordium. Orthologous to human EIF4G3 (eukaryotic translation initiation factor 4 gamma 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 43.2), CNS E11.5 (RPKM 29.8) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Eif4g3 in Genome Data Viewer
    Location:
    4; 4 D3
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (137719090..137934397)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (137991779..138207086)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_11797 Neighboring gene endothelin converting enzyme 1 Neighboring gene predicted gene 13012 Neighboring gene predicted gene, 52683 Neighboring gene STARR-positive B cell enhancer mm9_chr4:137508798-137509099 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:137524336-137524519 Neighboring gene STARR-positive B cell enhancer mm9_chr4:137549212-137549513 Neighboring gene STARR-seq mESC enhancer starr_11798 Neighboring gene STARR-positive B cell enhancer ABC_E6242 Neighboring gene RIKEN cDNA 1700095J12 gene Neighboring gene microRNA 6399 Neighboring gene heterochromatin protein 1, binding protein 3 Neighboring gene SH2 domain containing 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Assessing eukaryotic initiation factor 4F subunit essentiality by CRISPR-induced gene ablation in the mouse. Sénéchal P, et al. Cell Mol Life Sci, 2021 Oct. PMID 34559254, Free PMC Article
    2. Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes. Sun F, et al. Development, 2010 May. PMID 20430745, Free PMC Article
    3. Reduced DEAF1 function during type 1 diabetes inhibits translation in lymph node stromal cells by suppressing Eif4g3. Yip L, et al. J Mol Cell Biol, 2013 Apr. PMID 22923498, Free PMC Article
    4. Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions. Gonatopoulos-Pournatzis T, et al. Mol Cell, 2020 Mar 19. PMID 31999954
    5. Alcohol and indinavir adversely affect protein synthesis and phosphorylation of MAPK and mTOR signaling pathways in C2C12 myocytes. Hong-Brown LQ, et al. Alcohol Clin Exp Res, 2006 Aug. PMID 16899032

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The results of this study showed that EIF4G3 is located in the nucleus of spermatocytes, where it is highly enriched in the XY body, the chromatin domain formed by the transcriptionally inactive sex chromosomes.
      Title: Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice.
    2. reduced DEAF1 function, and subsequent loss of Eif4g3 transcription may affect peripheral tissue antigen (PTA) expression in LNSCs and contribute to the pathology of T1D.
      Title: Reduced DEAF1 function during type 1 diabetes inhibits translation in lymph node stromal cells by suppressing Eif4g3.
    3. EIF4G3 is required for HSPA2 translation in spermatocytes and mutations can cause male infertility.
      Title: Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1) 
    • Endonuclease-mediated (2)  1 citation
    • Gene trapped (1) 
    • Targeted (3)  1 citation

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • 4833436O05

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables translation initiation factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of meiosis I IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of protein phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of translation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spermatid development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translational initiation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of eukaryotic translation initiation factor 4F complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of eukaryotic translation initiation factor 4F complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in intracellular membraneless organelle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    eukaryotic translation initiation factor 4 gamma 3
    Names
    eIF-4-gamma 3
    eIF-4-gamma II

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001256195.1 → NP_001243124.1  eukaryotic translation initiation factor 4 gamma 3 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR and lacks an alternate, in-frame, exon in the 5' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1.
      Source sequence(s)
      AK019693, BC079885, BE852849, CX566741
      UniProtKB/TrEMBL
      Z4YKC4
      Related
      ENSMUSP00000101457.3, ENSMUST00000105831.9
      Conserved Domains (5) summary
      cd11559
      Location:1406 → 1538
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      pfam02847
      Location:1204 → 1316
      MA3; MA3 domain
      pfam02854
      Location:757 → 985
      MIF4G; MIF4G domain
      pfam11235
      Location:171 → 331
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1517 → 1563
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    2. NM_001256198.1 → NP_001243127.1  eukaryotic translation initiation factor 4 gamma 3 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate exon in the 5' UTR and lacks an alternate, in-frame, exon in the 3' coding region which causes a shift in the reading frame, compared to variant 1. The resulting protein (isoform 3) has a shorter and distinct C-terminus when it is compared to isoform 1.
      Source sequence(s)
      AK019693, BC082549, BE852849, CX566741
      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (2) summary
      pfam02847
      Location:1223 → 1335
      MA3; MA3 domain
      pfam02854
      Location:757 → 985
      MIF4G; MIF4G domain

    3. NM_001355699.1 → NP_001342628.1  eukaryotic translation initiation factor 4 gamma 3 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AK029440, AL807747, BE852849, CX566741
      UniProtKB/TrEMBL
      Z4YKC4
      Conserved Domains (5) summary
      cd11559
      Location:1448 → 1580
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      pfam02847
      Location:1246 → 1358
      MA3; MA3 domain
      pfam02854
      Location:799 → 1027
      MIF4G; MIF4G domain
      cl17013
      Location:1559 → 1605
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon
      cl26386
      Location:210 → 374
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

    4. NM_001355700.1 → NP_001342629.1  eukaryotic translation initiation factor 4 gamma 3 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AK029440, AL807747, BE852849, CX566741
      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (4) summary
      cd11559
      Location:1169 → 1301
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      pfam02847
      Location:967 → 1079
      MA3; MA3 domain
      pfam02854
      Location:501 → 729
      MIF4G; MIF4G domain
      cl17013
      Location:1280 → 1326
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    5. NM_001369130.1 → NP_001356059.1  eukaryotic translation initiation factor 4 gamma 3 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) encodes the longest isoform (6).
      Source sequence(s)
      AL807747, AL929388
      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1456 → 1588
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:4 → 369
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1254 → 1366
      MA3; MA3 domain
      pfam02854
      Location:788 → 1016
      MIF4G; MIF4G domain
      pfam11235
      Location:202 → 362
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1567 → 1613
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    6. NM_001369131.1 → NP_001356060.1  eukaryotic translation initiation factor 4 gamma 3 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AK046639, AL807747
      Consensus CDS
      CCDS89847.1
      UniProtKB/TrEMBL
      Q8BQR8
      Related
      ENSMUSP00000059465.4, ENSMUST00000058133.10
      Conserved Domains (1) summary
      PRK14954
      Location:153 → 235
      PRK14954; DNA polymerase III subunits gamma and tau; Provisional

    7. NM_172703.3 → NP_766291.2  eukaryotic translation initiation factor 4 gamma 3 isoform 1

      See identical proteins and their annotated locations for NP_766291.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      BC072600, BE852849, BY310944, CX566741
      Consensus CDS
      CCDS38926.1
      UniProtKB/TrEMBL
      A0A0R4J112, Z4YKC4
      Related
      ENSMUSP00000081232.6, ENSMUST00000084214.12
      Conserved Domains (4) summary
      cd11559
      Location:1417 → 1549
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      pfam02847
      Location:1215 → 1327
      MA3; MA3 domain
      pfam02854
      Location:768 → 996
      MIF4G; MIF4G domain
      cl17013
      Location:1528 → 1574
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    RNA

    1. NR_161160.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL807747

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      137719090..137934397
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538776.4 → XP_006538839.1  eukaryotic translation initiation factor 4 gamma 3 isoform X1

      UniProtKB/TrEMBL
      A0A0N4SVL0
      Conserved Domains (5) summary
      cd11559
      Location:1612 → 1744
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 472
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1410 → 1522
      MA3; MA3 domain
      pfam02854
      Location:944 → 1172
      MIF4G; MIF4G domain
      cl17013
      Location:1723 → 1769
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    2. XM_006538779.4 → XP_006538842.1  eukaryotic translation initiation factor 4 gamma 3 isoform X3

      UniProtKB/TrEMBL
      A0A0N4SVL0
      Conserved Domains (5) summary
      cd11559
      Location:1585 → 1717
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 476
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1383 → 1495
      MA3; MA3 domain
      pfam02854
      Location:917 → 1145
      MIF4G; MIF4G domain
      cl17013
      Location:1696 → 1742
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    3. XM_036164070.1 → XP_036019963.1  eukaryotic translation initiation factor 4 gamma 3 isoform X11

      UniProtKB/TrEMBL
      A0A0N4SVL0
      Conserved Domains (5) summary
      cd11559
      Location:1566 → 1698
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 476
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1364 → 1476
      MA3; MA3 domain
      pfam02854
      Location:917 → 1145
      MIF4G; MIF4G domain
      cl17013
      Location:1677 → 1723
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    4. XM_030253471.1 → XP_030109331.1  eukaryotic translation initiation factor 4 gamma 3 isoform X4

      UniProtKB/TrEMBL
      A0A0N4SVL0
      Conserved Domains (5) summary
      cd11559
      Location:1584 → 1716
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 475
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1382 → 1494
      MA3; MA3 domain
      pfam02854
      Location:916 → 1144
      MIF4G; MIF4G domain
      cl17013
      Location:1695 → 1741
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    5. XM_017320166.2 → XP_017175655.1  eukaryotic translation initiation factor 4 gamma 3 isoform X5

      UniProtKB/TrEMBL
      A0A0N4SVL0
      Conserved Domains (5) summary
      cd11559
      Location:1581 → 1713
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 472
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1379 → 1491
      MA3; MA3 domain
      pfam02854
      Location:913 → 1141
      MIF4G; MIF4G domain
      cl17013
      Location:1692 → 1738
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    6. XM_017320167.2 → XP_017175656.1  eukaryotic translation initiation factor 4 gamma 3 isoform X7

      UniProtKB/TrEMBL
      A0A0N4SVL0
      Related
      ENSMUSP00000159837.1, ENSMUST00000249658.1
      Conserved Domains (5) summary
      cd11559
      Location:1574 → 1706
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 465
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1372 → 1484
      MA3; MA3 domain
      pfam02854
      Location:906 → 1134
      MIF4G; MIF4G domain
      cl17013
      Location:1685 → 1731
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    7. XM_036164071.1 → XP_036019964.1  eukaryotic translation initiation factor 4 gamma 3 isoform X12

      UniProtKB/TrEMBL
      A0A0N4SVL0
      Conserved Domains (5) summary
      cd11559
      Location:1555 → 1687
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 465
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1353 → 1465
      MA3; MA3 domain
      pfam02854
      Location:906 → 1134
      MIF4G; MIF4G domain
      cl17013
      Location:1666 → 1712
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    8. XM_030253473.2 → XP_030109333.1  eukaryotic translation initiation factor 4 gamma 3 isoform X8

      UniProtKB/TrEMBL
      A0A0N4SVL0
      Conserved Domains (5) summary
      cd11559
      Location:1573 → 1705
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 464
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1371 → 1483
      MA3; MA3 domain
      pfam02854
      Location:905 → 1133
      MIF4G; MIF4G domain
      cl17013
      Location:1684 → 1730
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    9. XM_036164068.1 → XP_036019961.1  eukaryotic translation initiation factor 4 gamma 3 isoform X2

      UniProtKB/TrEMBL
      A0A0N4SVL0
      Conserved Domains (5) summary
      cd11559
      Location:1605 → 1737
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 518
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1403 → 1515
      MA3; MA3 domain
      pfam02854
      Location:937 → 1165
      MIF4G; MIF4G domain
      cl17013
      Location:1716 → 1762
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    10. XM_030253472.2 → XP_030109332.1  eukaryotic translation initiation factor 4 gamma 3 isoform X6

      UniProtKB/TrEMBL
      A0A0N4SVL0
      Conserved Domains (5) summary
      cd11559
      Location:1578 → 1710
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:62 → 491
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1376 → 1488
      MA3; MA3 domain
      pfam02854
      Location:910 → 1138
      MIF4G; MIF4G domain
      cl17013
      Location:1689 → 1735
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    11. XM_030253474.1 → XP_030109334.1  eukaryotic translation initiation factor 4 gamma 3 isoform X10

      UniProtKB/TrEMBL
      A0A0N4SVL0
      Conserved Domains (5) summary
      cd11559
      Location:1567 → 1699
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 480
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1365 → 1477
      MA3; MA3 domain
      pfam02854
      Location:899 → 1127
      MIF4G; MIF4G domain
      cl17013
      Location:1678 → 1724
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    12. XM_036164069.1 → XP_036019962.1  eukaryotic translation initiation factor 4 gamma 3 isoform X9

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (5) summary
      cd11559
      Location:1569 → 1701
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:62 → 482
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1367 → 1479
      MA3; MA3 domain
      pfam02854
      Location:901 → 1129
      MIF4G; MIF4G domain
      cl17013
      Location:1680 → 1726
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    13. XM_030253475.1 → XP_030109335.1  eukaryotic translation initiation factor 4 gamma 3 isoform X13

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (5) summary
      cd11559
      Location:1542 → 1674
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 449
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1340 → 1452
      MA3; MA3 domain
      pfam02854
      Location:874 → 1102
      MIF4G; MIF4G domain
      cl17013
      Location:1653 → 1699
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    14. XM_036164073.1 → XP_036019966.1  eukaryotic translation initiation factor 4 gamma 3 isoform X18

      UniProtKB/TrEMBL
      Z4YKC4
      Conserved Domains (5) summary
      cd11559
      Location:1523 → 1655
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 449
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1321 → 1433
      MA3; MA3 domain
      pfam02854
      Location:874 → 1102
      MIF4G; MIF4G domain
      cl17013
      Location:1634 → 1680
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    15. XM_036164072.1 → XP_036019965.1  eukaryotic translation initiation factor 4 gamma 3 isoform X14

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (5) summary
      cd11559
      Location:1541 → 1673
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:62 → 454
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1339 → 1451
      MA3; MA3 domain
      pfam02854
      Location:873 → 1101
      MIF4G; MIF4G domain
      cl17013
      Location:1652 → 1698
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    16. XM_036164083.1 → XP_036019976.1  eukaryotic translation initiation factor 4 gamma 3 isoform X32

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (4) summary
      cd11559
      Location:1169 → 1301
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      pfam02847
      Location:967 → 1079
      MA3; MA3 domain
      pfam02854
      Location:501 → 729
      MIF4G; MIF4G domain
      cl17013
      Location:1280 → 1326
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    17. XM_006538785.4 → XP_006538848.1  eukaryotic translation initiation factor 4 gamma 3 isoform X15

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1538 → 1670
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:57 → 445
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1336 → 1448
      MA3; MA3 domain
      pfam02854
      Location:870 → 1098
      MIF4G; MIF4G domain
      pfam09770
      Location:57 → 197
      PAT1; Topoisomerase II-associated protein PAT1
      cl17013
      Location:1649 → 1695
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    18. XM_030253476.1 → XP_030109336.1  eukaryotic translation initiation factor 4 gamma 3 isoform X16

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (5) summary
      cd11559
      Location:1531 → 1663
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      pfam02847
      Location:1329 → 1441
      MA3; MA3 domain
      pfam02854
      Location:863 → 1091
      MIF4G; MIF4G domain
      pfam03154
      Location:61 → 395
      Atrophin-1; Atrophin-1 family
      cl17013
      Location:1642 → 1688
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    19. XM_030253477.1 → XP_030109337.1  eukaryotic translation initiation factor 4 gamma 3 isoform X17

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (5) summary
      cd11559
      Location:1530 → 1662
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      pfam02847
      Location:1328 → 1440
      MA3; MA3 domain
      pfam02854
      Location:862 → 1090
      MIF4G; MIF4G domain
      pfam03154
      Location:61 → 394
      Atrophin-1; Atrophin-1 family
      cl17013
      Location:1641 → 1687
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    20. XM_030253481.1 → XP_030109341.1  eukaryotic translation initiation factor 4 gamma 3 isoform X19

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1456 → 1588
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:4 → 369
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1254 → 1366
      MA3; MA3 domain
      pfam02854
      Location:788 → 1016
      MIF4G; MIF4G domain
      pfam11235
      Location:202 → 362
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1567 → 1613
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    21. XM_030253486.1 → XP_030109346.1  eukaryotic translation initiation factor 4 gamma 3 isoform X21

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1429 → 1561
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:2 → 342
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1227 → 1339
      MA3; MA3 domain
      pfam02854
      Location:761 → 989
      MIF4G; MIF4G domain
      pfam11235
      Location:175 → 335
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1540 → 1586
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    22. XM_036164074.1 → XP_036019967.1  eukaryotic translation initiation factor 4 gamma 3 isoform X22

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1428 → 1560
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:2 → 341
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:172 → 335
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1226 → 1338
      MA3; MA3 domain
      pfam02854
      Location:760 → 988
      MIF4G; MIF4G domain
      cl17013
      Location:1539 → 1585
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    23. XM_036164080.1 → XP_036019973.1  eukaryotic translation initiation factor 4 gamma 3 isoform X30

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (5) summary
      cd11559
      Location:1280 → 1412
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PRK07003
      Location:23 → 187
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1078 → 1190
      MA3; MA3 domain
      pfam02854
      Location:612 → 840
      MIF4G; MIF4G domain
      cl17013
      Location:1391 → 1437
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    24. XM_006538793.4 → XP_006538856.1  eukaryotic translation initiation factor 4 gamma 3 isoform X23

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1425 → 1557
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:6 → 338
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1223 → 1335
      MA3; MA3 domain
      pfam02854
      Location:757 → 985
      MIF4G; MIF4G domain
      pfam11235
      Location:171 → 331
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1536 → 1582
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    25. XM_006538794.4 → XP_006538857.1  eukaryotic translation initiation factor 4 gamma 3 isoform X24

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      UniProtKB/TrEMBL
      A2AMI2
      Related
      ENSMUSP00000081233.6, ENSMUST00000084215.12
      Conserved Domains (6) summary
      cd11559
      Location:1418 → 1550
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PRK10263
      Location:10 → 315
      PRK10263; DNA translocase FtsK; Provisional
      pfam02847
      Location:1216 → 1328
      MA3; MA3 domain
      pfam02854
      Location:750 → 978
      MIF4G; MIF4G domain
      pfam11235
      Location:164 → 324
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1529 → 1575
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    26. XM_030253492.1 → XP_030109352.1  eukaryotic translation initiation factor 4 gamma 3 isoform X25

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1417 → 1549
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:5 → 340
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:161 → 324
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1215 → 1327
      MA3; MA3 domain
      pfam02854
      Location:749 → 977
      MIF4G; MIF4G domain
      cl17013
      Location:1528 → 1574
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    27. XM_036164078.1 → XP_036019971.1  eukaryotic translation initiation factor 4 gamma 3 isoform X29

      UniProtKB/TrEMBL
      Z4YKC4
      Conserved Domains (6) summary
      cd11559
      Location:1398 → 1530
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:5 → 340
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:161 → 324
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1196 → 1308
      MA3; MA3 domain
      pfam02854
      Location:749 → 977
      MIF4G; MIF4G domain
      cl17013
      Location:1509 → 1555
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    28. XM_030253498.1 → XP_030109358.1  eukaryotic translation initiation factor 4 gamma 3 isoform X32

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (4) summary
      cd11559
      Location:1169 → 1301
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      pfam02847
      Location:967 → 1079
      MA3; MA3 domain
      pfam02854
      Location:501 → 729
      MIF4G; MIF4G domain
      cl17013
      Location:1280 → 1326
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    29. XM_036164084.1 → XP_036019977.1  eukaryotic translation initiation factor 4 gamma 3 isoform X33

      UniProtKB/TrEMBL
      Z4YKC4
      Conserved Domains (4) summary
      cd11559
      Location:1150 → 1282
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      pfam02847
      Location:948 → 1060
      MA3; MA3 domain
      pfam02854
      Location:501 → 729
      MIF4G; MIF4G domain
      cl17013
      Location:1261 → 1307
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    30. XM_030253496.1 → XP_030109356.1  eukaryotic translation initiation factor 4 gamma 3 isoform X31

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (5) summary
      cd11559
      Location:1279 → 1411
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PRK07003
      Location:23 → 186
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1077 → 1189
      MA3; MA3 domain
      pfam02854
      Location:611 → 839
      MIF4G; MIF4G domain
      cl17013
      Location:1390 → 1436
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    31. XM_030253499.1 → XP_030109359.1  eukaryotic translation initiation factor 4 gamma 3 isoform X32

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (4) summary
      cd11559
      Location:1169 → 1301
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      pfam02847
      Location:967 → 1079
      MA3; MA3 domain
      pfam02854
      Location:501 → 729
      MIF4G; MIF4G domain
      cl17013
      Location:1280 → 1326
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    32. XM_030253487.1 → XP_030109347.1  eukaryotic translation initiation factor 4 gamma 3 isoform X21

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1429 → 1561
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:2 → 342
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1227 → 1339
      MA3; MA3 domain
      pfam02854
      Location:761 → 989
      MIF4G; MIF4G domain
      pfam11235
      Location:175 → 335
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1540 → 1586
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    33. XM_036164076.1 → XP_036019969.1  eukaryotic translation initiation factor 4 gamma 3 isoform X26

      UniProtKB/TrEMBL
      Z4YKC4
      Conserved Domains (6) summary
      cd11559
      Location:1410 → 1542
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:2 → 342
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:172 → 336
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1208 → 1320
      MA3; MA3 domain
      pfam02854
      Location:761 → 989
      MIF4G; MIF4G domain
      cl17013
      Location:1521 → 1567
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    34. XM_036164075.1 → XP_036019968.1  eukaryotic translation initiation factor 4 gamma 3 isoform X22

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1428 → 1560
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:2 → 341
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:172 → 335
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1226 → 1338
      MA3; MA3 domain
      pfam02854
      Location:760 → 988
      MIF4G; MIF4G domain
      cl17013
      Location:1539 → 1585
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    35. XM_036164081.1 → XP_036019974.1  eukaryotic translation initiation factor 4 gamma 3 isoform X30

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (5) summary
      cd11559
      Location:1280 → 1412
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PRK07003
      Location:23 → 187
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1078 → 1190
      MA3; MA3 domain
      pfam02854
      Location:612 → 840
      MIF4G; MIF4G domain
      cl17013
      Location:1391 → 1437
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    36. XM_030253490.1 → XP_030109350.1  eukaryotic translation initiation factor 4 gamma 3 isoform X24

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      UniProtKB/TrEMBL
      A2AMI2
      Conserved Domains (6) summary
      cd11559
      Location:1418 → 1550
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PRK10263
      Location:10 → 315
      PRK10263; DNA translocase FtsK; Provisional
      pfam02847
      Location:1216 → 1328
      MA3; MA3 domain
      pfam02854
      Location:750 → 978
      MIF4G; MIF4G domain
      pfam11235
      Location:164 → 324
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1529 → 1575
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    37. XM_030253493.1 → XP_030109353.1  eukaryotic translation initiation factor 4 gamma 3 isoform X25

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1417 → 1549
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:5 → 340
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:161 → 324
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1215 → 1327
      MA3; MA3 domain
      pfam02854
      Location:749 → 977
      MIF4G; MIF4G domain
      cl17013
      Location:1528 → 1574
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    38. XM_006538790.4 → XP_006538853.1  eukaryotic translation initiation factor 4 gamma 3 isoform X19

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1456 → 1588
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:4 → 369
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1254 → 1366
      MA3; MA3 domain
      pfam02854
      Location:788 → 1016
      MIF4G; MIF4G domain
      pfam11235
      Location:202 → 362
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1567 → 1613
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    39. XM_030253488.1 → XP_030109348.1  eukaryotic translation initiation factor 4 gamma 3 isoform X21

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1429 → 1561
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:2 → 342
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1227 → 1339
      MA3; MA3 domain
      pfam02854
      Location:761 → 989
      MIF4G; MIF4G domain
      pfam11235
      Location:175 → 335
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1540 → 1586
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    40. XM_030253489.1 → XP_030109349.1  eukaryotic translation initiation factor 4 gamma 3 isoform X22

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1428 → 1560
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:2 → 341
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:172 → 335
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1226 → 1338
      MA3; MA3 domain
      pfam02854
      Location:760 → 988
      MIF4G; MIF4G domain
      cl17013
      Location:1539 → 1585
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    41. XM_030253491.1 → XP_030109351.1  eukaryotic translation initiation factor 4 gamma 3 isoform X24

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      UniProtKB/TrEMBL
      A2AMI2
      Conserved Domains (6) summary
      cd11559
      Location:1418 → 1550
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PRK10263
      Location:10 → 315
      PRK10263; DNA translocase FtsK; Provisional
      pfam02847
      Location:1216 → 1328
      MA3; MA3 domain
      pfam02854
      Location:750 → 978
      MIF4G; MIF4G domain
      pfam11235
      Location:164 → 324
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1529 → 1575
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    42. XM_036164077.1 → XP_036019970.1  eukaryotic translation initiation factor 4 gamma 3 isoform X28

      UniProtKB/TrEMBL
      Z4YKC4
      Conserved Domains (6) summary
      cd11559
      Location:1399 → 1531
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:5 → 341
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:161 → 325
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1197 → 1309
      MA3; MA3 domain
      pfam02854
      Location:750 → 978
      MIF4G; MIF4G domain
      cl17013
      Location:1510 → 1556
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    43. XM_030253494.2 → XP_030109354.1  eukaryotic translation initiation factor 4 gamma 3 isoform X25

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1417 → 1549
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:5 → 340
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:161 → 324
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1215 → 1327
      MA3; MA3 domain
      pfam02854
      Location:749 → 977
      MIF4G; MIF4G domain
      cl17013
      Location:1528 → 1574
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    44. XM_036164079.1 → XP_036019972.1  eukaryotic translation initiation factor 4 gamma 3 isoform X29

      UniProtKB/TrEMBL
      Z4YKC4
      Conserved Domains (6) summary
      cd11559
      Location:1398 → 1530
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:5 → 340
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:161 → 324
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1196 → 1308
      MA3; MA3 domain
      pfam02854
      Location:749 → 977
      MIF4G; MIF4G domain
      cl17013
      Location:1509 → 1555
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    45. XM_036164082.1 → XP_036019975.1  eukaryotic translation initiation factor 4 gamma 3 isoform X31

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (5) summary
      cd11559
      Location:1279 → 1411
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PRK07003
      Location:23 → 186
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1077 → 1189
      MA3; MA3 domain
      pfam02854
      Location:611 → 839
      MIF4G; MIF4G domain
      cl17013
      Location:1390 → 1436
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    46. XM_030253482.1 → XP_030109342.1  eukaryotic translation initiation factor 4 gamma 3 isoform X19

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1456 → 1588
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:4 → 369
      PHA03247; large tegument protein UL36; Provisional
      pfam02847
      Location:1254 → 1366
      MA3; MA3 domain
      pfam02854
      Location:788 → 1016
      MIF4G; MIF4G domain
      pfam11235
      Location:202 → 362
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      cl17013
      Location:1567 → 1613
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    47. XM_030253484.1 → XP_030109344.1  eukaryotic translation initiation factor 4 gamma 3 isoform X20

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1455 → 1587
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:4 → 368
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:199 → 362
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1253 → 1365
      MA3; MA3 domain
      pfam02854
      Location:787 → 1015
      MIF4G; MIF4G domain
      cl17013
      Location:1566 → 1612
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    48. XM_006538795.4 → XP_006538858.1  eukaryotic translation initiation factor 4 gamma 3 isoform X27

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (6) summary
      cd11559
      Location:1424 → 1556
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PHA03247
      Location:6 → 337
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:168 → 331
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1222 → 1334
      MA3; MA3 domain
      pfam02854
      Location:756 → 984
      MIF4G; MIF4G domain
      cl17013
      Location:1535 → 1581
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

    49. XM_030253497.1 → XP_030109357.1  eukaryotic translation initiation factor 4 gamma 3 isoform X31

      UniProtKB/Swiss-Prot
      Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
      Conserved Domains (5) summary
      cd11559
      Location:1279 → 1411
      W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
      PRK07003
      Location:23 → 186
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam02847
      Location:1077 → 1189
      MA3; MA3 domain
      pfam02854
      Location:611 → 839
      MIF4G; MIF4G domain
      cl17013
      Location:1390 → 1436
      W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q80XI3.2 GenPept UniProtKB/Swiss-Prot:Q80XI3

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