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    AdipoR Adiponectin receptor [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42656, updated on 9-Dec-2024

    Summary

    Official Symbol
    AdipoRprovided by FlyBase
    Official Full Name
    Adiponectin receptorprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038984
    Locus tag
    Dmel_CG5315
    See related
    AllianceGenome:FB:FBgn0038984
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5315; dAdipoR; Dmel\CG5315
    Summary
    Predicted to enable protein-hormone receptor activity. Involved in several processes, including female germ-line stem cell population maintenance; positive regulation of insulin secretion; and triglyceride homeostasis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adult head; anterior endoderm; embryonic/larval midgut; embryonic/larval midgut primordium; and larval circulatory system. Human ortholog(s) of this gene implicated in breast cancer; macular degeneration; metabolic dysfunction-associated steatotic liver disease; prostate adenocarcinoma; and type 2 diabetes mellitus. Orthologous to several human genes including ADIPOR1 (adiponectin receptor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See AdipoR in Genome Data Viewer
    Location:
    94B3-94B3; 3-75 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (22543693..22547846, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (18369415..18373568, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45646 Neighboring gene long non-coding RNA:CR45647 Neighboring gene antisense RNA:CR44062 Neighboring gene james bond Neighboring gene stuck in traffic

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-hormone receptor activity PubMed 
    enables signaling receptor activity  
    Component Evidence Code Pubs
    located_in membrane  
    located_in membrane PubMed 
    is_active_in plasma membrane  

    General protein information

    Preferred Names
    adiponectin receptor
    Names
    AdipoR-PA
    AdipoR-PB
    AdipoR-PC
    AdipoR-PD
    AdipoR-PE
    CG5315-PA
    CG5315-PB
    CG5315-PC
    CG5315-PD
    CG5315-PE

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      22543693..22547846 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142804.3 → NP_651061.1  adiponectin receptor, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651061.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VCY8, Q9VCY9
      UniProtKB/TrEMBL
      A4V392
      Related
      FBpp0083675
      Conserved Domains (1) summary
      pfam03006
      Location:198 → 419
      HlyIII; Haemolysin-III related
    2. NM_170019.2 → NP_732758.1  adiponectin receptor, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732758.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VCY8, Q9VCY9
      UniProtKB/TrEMBL
      A4V392
      Related
      FBpp0083676
      Conserved Domains (1) summary
      pfam03006
      Location:198 → 419
      HlyIII; Haemolysin-III related
    3. NM_001260310.2 → NP_001247239.1  adiponectin receptor, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247239.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VCY8, Q9VCY9
      UniProtKB/TrEMBL
      A4V392
      Conserved Domains (1) summary
      pfam03006
      Location:198 → 419
      HlyIII; Haemolysin-III related
    4. NM_001275915.1 → NP_001262844.1  adiponectin receptor, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262844.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VCY8, Q9VCY9
      UniProtKB/TrEMBL
      A4V392
      Conserved Domains (1) summary
      pfam03006
      Location:198 → 419
      HlyIII; Haemolysin-III related
    5. NM_170020.2 → NP_732759.2  adiponectin receptor, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732759.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      C6TP81
      Related
      FBpp0083677
      Conserved Domains (1) summary
      pfam03006
      Location:116 → 337
      HlyIII; Haemolysin-III related
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