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    RPL33A ribosomal 60S subunit protein L33A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855960, updated on 5-Jan-2025

    Summary

    Official Symbol
    RPL33A
    Official Full Name
    ribosomal 60S subunit protein L33A
    Primary source
    SGD:S000006064
    Locus tag
    YPL143W
    See related
    AllianceGenome:SGD:S000006064; FungiDB:YPL143W; VEuPathDB:YPL143W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    GCD17; RPL37A
    Summary
    A structural constituent of ribosome. Involved in cytoplasmic translation; rRNA processing; and ribosomal large subunit assembly. Part of cytosolic large ribosomal subunit. Used to study Diamond-Blackfan anemia. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 5. Orthologous to human RPL35A (ribosomal protein L35a). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See RPL33A in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    2
    Sequence:
    Chromosome: XVI; NC_001148.4 (282122..282970)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Poc4p Neighboring gene ncRNA Neighboring gene protein kinase FRK1 Neighboring gene putative mitogen-activated protein kinase kinase MKK2

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Process Evidence Code Pubs
    involved_in cytoplasmic translation  
    involved_in cytoplasmic translation PubMed 
    involved_in rRNA processing PubMed 
    involved_in ribosomal large subunit assembly PubMed 
    involved_in ribosomal large subunit biogenesis  
    involved_in translation  
    Component Evidence Code Pubs
    located_in cytoplasm  
    part_of cytosolic large ribosomal subunit  
    part_of cytosolic large ribosomal subunit PubMed 
    part_of ribonucleoprotein complex  
    located_in ribosome  

    General protein information

    Preferred Names
    ribosomal 60S subunit protein L33A
    NP_015182.1
    • Ribosomal 60S subunit protein L33A; N-terminally acetylated; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable; homologous to mammalian ribosomal protein L35A, no bacterial homolog; RPL33A has a paralog, RPL33B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      282122..282970
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183957.1 → NP_015182.1  TPA: ribosomal 60S subunit protein L33A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015182.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3M6, P05744
      UniProtKB/TrEMBL
      A6ZWB1, C7GJ94, C8ZIN6, G2WP40, N1NVG1
      Conserved Domains (1) summary
      pfam01247
      Location:7 → 100
      Ribosomal_L35Ae; Ribosomal protein L35Ae
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