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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011554.1 RefSeqGene
- Range
-
5029..58383
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_002775.5 → NP_002766.1 serine protease HTRA1 precursor
Status: REVIEWED
- Source sequence(s)
-
DA633502, Y07921
- Consensus CDS
-
CCDS7630.1
- UniProtKB/Swiss-Prot
- D3DRE4, Q92743, Q9UNS5
- Related
- ENSP00000357980.3, ENST00000368984.8
- Conserved Domains (5) summary
-
- smart00121
Location:35 → 111
- IB; Insulin growth factor-binding protein homologues
- smart00280
Location:115 → 155
- KAZAL; Kazal type serine protease inhibitors
- COG0265
Location:154 → 480
- DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
- cd00987
Location:382 → 473
- PDZ_serine_protease; PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind ...
- pfam13365
Location:204 → 342
- Trypsin_2; Trypsin-like peptidase domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000010.11 Reference GRCh38.p14 Primary Assembly
- Range
-
122461553..122514907
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060934.1 Alternate T2T-CHM13v2.0
- Range
-
123357406..123410753
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)