U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    fru fruitless [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42226, updated on 9-Dec-2024

    Summary

    Official Symbol
    fruprovided by FlyBase
    Official Full Name
    fruitlessprovided by FlyBase
    Primary source
    FLYBASE:FBgn0004652
    Locus tag
    Dmel_CG14307
    See related
    AllianceGenome:FB:FBgn0004652
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BTB-VI; BtbVI; CG14307; cg7688; CG7688; cg7689; CG7689; CG7690; CT22773; Dmel\CG14307; Dmfru; Fru; FRU; FRU-PI; fruC; FruM; fry; fty; ms(3)06411; sat
    Summary
    Predicted to enable DNA-binding transcription factor activity. Involved in several processes, including male courtship behavior; mating behavior, sex discrimination; and neuron development. Predicted to be active in nucleus. Is expressed in several structures, including epithelium; neuroblast lineage clone; neurons; organism subdivision; and synaptic neuropil subdomain. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See fru in Genome Data Viewer
    Location:
    91A6-91B3; 3-64 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18414273..18545586, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14239995..14371308, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene hemotin

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    mobile_element

    • Loc: c18465625-18465569 mobile_element_type = transposon:Doc3{}5636

    Gene Ontology Provided by FlyBase

    Items 1 - 25 of 27
    Process Evidence Code Pubs
    involved_in aggressive behavior PubMed 
    involved_in axon midline choice point recognition PubMed 
    involved_in central nervous system development PubMed 
    involved_in central nervous system development PubMed 
    involved_in central nervous system neuron development PubMed 
    involved_in copulation PubMed 
    involved_in copulation PubMed 
    involved_in dendrite morphogenesis PubMed 
    involved_in male courtship behavior PubMed 
    involved_in male courtship behavior PubMed 
    involved_in male courtship behavior PubMed 
    involved_in male courtship behavior, orientation prior to leg tapping and wing vibration PubMed 
    involved_in male courtship behavior, tapping to detect pheromone PubMed 
    involved_in male courtship behavior, veined wing extension PubMed 
    involved_in male courtship behavior, veined wing generated song production PubMed 
    involved_in male courtship behavior, veined wing generated song production PubMed 
    involved_in male courtship behavior, veined wing vibration PubMed 
    involved_in male mating behavior PubMed 
    involved_in male sex differentiation PubMed 
    involved_in mating behavior PubMed 
    involved_in mating behavior, sex discrimination PubMed 
    involved_in mating behavior, sex discrimination PubMed 
    involved_in mating behavior, sex discrimination PubMed 
    involved_in muscle organ development PubMed 
    involved_in regulation of transcription by RNA polymerase II  
    involved_in sex determination PubMed 
    involved_in sex determination PubMed 
    Items 1 - 25 of 27
    Component Evidence Code Pubs
    is_active_in nucleus  

    General protein information

    Preferred Names
    fruitless
    Names
    BTB-protein-VI
    CG14307-PA
    CG14307-PB
    CG14307-PC
    CG14307-PD
    CG14307-PE
    CG14307-PF
    CG14307-PG
    CG14307-PH
    CG14307-PI
    CG14307-PJ
    CG14307-PK
    CG14307-PL
    CG14307-PM
    CG14307-PN
    CG14307-PO
    fru-PA
    fru-PB
    fru-PC
    fru-PD
    fru-PE
    fru-PF
    fru-PG
    fru-PH
    fru-PI
    fru-PJ
    fru-PK
    fru-PL
    fru-PM
    fru-PN
    fru-PO
    fru-satori
    fruity
    satori

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18414273..18545586 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079673.3 → NP_524397.2  fruitless, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524397.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Related
      FBpp0083064
      Conserved Domains (5) summary
      smart00225
      Location:31 → 115
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00614
      Location:643 → 680
      ZnF_BED; BED zinc finger
      sd00017
      Location:632 → 649
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:20 → 115
      BTB; BTB/POZ domain
      cl19237
      Location:615 → 666
      DUF45; Protein of unknown function DUF45
    2. NM_169816.2 → NP_732344.1  fruitless, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732344.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Related
      FBpp0083061
      Conserved Domains (3) summary
      smart00614
      Location:744 → 781
      ZnF_BED; BED zinc finger
      sd00017
      Location:733 → 750
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18315
      Location:130 → 213
      BTB_POZ_BAB-like; BTB (Broad-Complex, Tramtrack and Bric a brac) /POZ (poxvirus and zinc finger) domain found in Drosophila melanogaster proteins bric-a-brac 1 (BAB1), bric-a-brac 2 (BAB2), modifier of mdg4 (doom), and similar proteins
    3. NM_169817.2 → NP_732345.1  fruitless, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732345.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Related
      FBpp0083065
      Conserved Domains (2) summary
      sd00019
      Location:638 → 655
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18315
      Location:130 → 213
      BTB_POZ_BAB-like; BTB (Broad-Complex, Tramtrack and Bric a brac) /POZ (poxvirus and zinc finger) domain found in Drosophila melanogaster proteins bric-a-brac 1 (BAB1), bric-a-brac 2 (BAB2), modifier of mdg4 (doom), and similar proteins
    4. NM_169818.2 → NP_732346.1  fruitless, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732346.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Related
      FBpp0083060
      Conserved Domains (3) summary
      smart00225
      Location:31 → 115
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:561 → 577
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:20 → 115
      BTB; BTB/POZ domain
    5. NM_001275783.1 → NP_001262712.1  fruitless, isoform O [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262712.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KG97
      Conserved Domains (3) summary
      smart00225
      Location:31 → 115
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:537 → 554
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:20 → 115
      BTB; BTB/POZ domain
    6. NM_206514.2 → NP_996236.1  fruitless, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996236.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Conserved Domains (3) summary
      smart00225
      Location:41 → 125
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:571 → 587
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:30 → 125
      BTB; BTB/POZ domain
    7. NM_169819.2 → NP_732347.1  fruitless, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732347.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V334, O44708, P91618, P91619, Q24004, Q29QE0, Q7KSD2, Q7KSD5, Q7KSD6, Q8IN80, Q8IN81, Q8IN82, Q8IN83, Q8IS35, Q8IS36, Q9GU18, Q9GU19, Q9GU20, Q9GU21, Q9GU22, Q9VE64, Q9VE65, Q9VE66, Q9VE67
      Related
      FBpp0083063
      Conserved Domains (3) summary
      smart00225
      Location:132 → 216
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:896 → 913
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:121 → 216
      BTB; BTB/POZ domain
    8. NM_001170177.2 → NP_001163648.1  fruitless, isoform N [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163648.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JIP5
      Conserved Domains (3) summary
      smart00225
      Location:137 → 221
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:901 → 918
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:126 → 221
      BTB; BTB/POZ domain
    9. NM_169820.2 → NP_732348.1  fruitless, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732348.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Related
      FBpp0083062
      Conserved Domains (3) summary
      smart00225
      Location:31 → 115
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:795 → 812
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:20 → 115
      BTB; BTB/POZ domain
    10. NM_206516.2 → NP_996238.1  fruitless, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996238.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Conserved Domains (3) summary
      smart00225
      Location:47 → 131
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:811 → 828
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:36 → 131
      BTB; BTB/POZ domain
    11. NM_206515.2 → NP_996237.1  fruitless, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996237.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Conserved Domains (3) summary
      smart00225
      Location:83 → 167
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:847 → 864
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:72 → 167
      BTB; BTB/POZ domain
    12. NM_206513.2 → NP_996235.1  fruitless, isoform L [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996235.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Conserved Domains (3) summary
      smart00225
      Location:31 → 115
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:795 → 812
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:20 → 115
      BTB; BTB/POZ domain
    13. NM_206512.2 → NP_996234.1  fruitless, isoform M [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996234.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Conserved Domains (3) summary
      smart00225
      Location:31 → 115
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:795 → 812
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:20 → 115
      BTB; BTB/POZ domain
    14. NM_169821.2 → NP_732349.1  fruitless, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732349.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Related
      FBpp0083066
      Conserved Domains (2) summary
      smart00225
      Location:31 → 115
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:20 → 115
      BTB; BTB/POZ domain
    15. NM_169822.2 → NP_732350.1  fruitless, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732350.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN81
      Related
      FBpp0083067
      Conserved Domains (3) summary
      smart00225
      Location:31 → 115
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00597
      Location:559 → 634
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam00651
      Location:20 → 115
      BTB; BTB/POZ domain
    External link. Please review our privacy policy.