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    txdc-12.1 Thioredoxin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174863, updated on 9-Dec-2024

    Summary

    Official Symbol
    txdc-12.1
    Official Full Name
    Thioredoxin domain-containing protein
    Primary source
    WormBase:WBGene00013263
    Locus tag
    CELE_Y57A10A.23
    See related
    AllianceGenome:WB:WBGene00013263
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in endoplasmic reticulum. Orthologous to several human genes including TXNDC12 (thioredoxin domain containing 12). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See txdc-12.1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (12240388..12242085)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene EB domain-containing protein Neighboring gene Uncharacterized protein

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum  

    General protein information

    Preferred Names
    Thioredoxin domain-containing protein
    NP_001370077.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12240388..12242085
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383970.2NP_001370077.1  Thioredoxin domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NA78
      Conserved Domains (1) summary
      cd02959
      Location:35155
      ERp19; Endoplasmic reticulum protein 19 (ERp19) family; ERp19 is also known as ERp18, a protein located in the ER containing one redox active TRX domain. Denaturation studies indicate that the reduced form is more stable than the oxidized form, suggesting that ...
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