IFT88 intraflagellar transport 88 [Homo sapiens (human)] - Gene

Summary

Official Symbol: IFT88provided by HGNC
Official Full Name: intraflagellar transport 88provided by HGNC
Primary source: HGNC:HGNC:20606
See related: Ensembl:ENSG00000032742 MIM:600595; AllianceGenome:HGNC:20606
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: DAF19; TG737; TTC10; hTg737; D13S1056E
Summary: This gene encodes a member of the tetratrico peptide repeat (TPR) family. The encoded protein is involved in cilium biogenesis. Mutations of a similar gene in mouse can cause polycystic kidney disease. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2017]
Expression: Broad expression in testis (RPKM 23.5), thyroid (RPKM 6.6) and 19 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 13q12.11

Exon count:: 33

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	13	NC_000013.11 (20567157..20691444)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	13	NC_060937.1 (19760320..19884580)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	13	NC_000013.10 (21141296..21265583)

Chromosome 13 - NC_000013.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Vinblastine Resistance Is Associated with Nephronophthisis 3-Mediated Primary Cilia via Intraflagellar Transport Protein 88 and Apoptosis-Antagonizing Transcription Factor.
Title: Vinblastine Resistance Is Associated with Nephronophthisis 3-Mediated Primary Cilia via Intraflagellar Transport Protein 88 and Apoptosis-Antagonizing Transcription Factor.
Multifaceted investigation underlies diverse mechanisms contributing to the downregulation of Hedgehog pathway-associated genes INTU and IFT88 in lung adenocarcinoma and uterine corpus endometrial carcinoma.
Title: Multifaceted investigation underlies diverse mechanisms contributing to the downregulation of Hedgehog pathway-associated genes INTU and IFT88 in lung adenocarcinoma and uterine corpus endometrial carcinoma.
IFT88 controls NuMA enrichment at k-fibers minus-ends to facilitate their re-anchoring into mitotic spindles.
Title: IFT88 controls NuMA enrichment at k-fibers minus-ends to facilitate their re-anchoring into mitotic spindles.
The Intraflagellar Transport Protein IFT88 Is Disrupted in Cystic Fibrosis.
Title: Ciliary Localization of the Intraflagellar Transport Protein IFT88 Is Disrupted in Cystic Fibrosis.
Significant association was found between IFT88 rs9509311 and rs2497490 and Nonsyndromic cleft lip with or without cleft palate (NSCLP) in non-Hispanic white families (p = .004 and .005), while nominal associations were found for rs7998361 and rs9509307 (p < .05). Pairwise association analyses also showed nominal associations between NSCLP in both NHW and Hispanic data sets (p < .05).
Title: Association of IFT88 gene variants with nonsyndromic cleft lip with or without cleft palate.
TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening
Title: Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening.
These observations suggest that the rare and unique combination of IFT88 alleles observed in this study provide insight into the physiological role of IFT88 in humans and the likely mechanism underlying retinal pathology in the pedigree with inherited retinal degeneration
Title: IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis.
IFT88/primary cilia play a role in metabolic reprogramming in thyroid cancer cells.
Title: Loss-of-function of IFT88 determines metabolic phenotypes in thyroid cancer.
BFGF also upregulated the mRNA and protein expression of IFT88 in primary cultured chondrocytes.
Title: Basic fibroblast growth factor increases IFT88 expression in chondrocytes.
Data suggest that the function of the fusion transcript crystallin, lambda 1 protein - intraflagellar transport 88 (CRYL1-IFT88) is closed to CRYL1 because it contained most of domain of CRYL1.
Title: Transcriptome profiling identifies a recurrent CRYL1-IFT88 chimeric transcript in hepatocellular carcinoma.

Submit: New GeneRIF Correction See all GeneRIFs (19)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genetics of coronary artery calcification among African Americans, a meta-analysis. EBI GWAS Catalog EBI GWAS CatalogPubMed
GWAS of dental caries patterns in the permanent dentition. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D8S2279 (e-PCR)
- UniSTS:473907

RH65721 (e-PCR)
- UniSTS:23612

SHGC-57879 (e-PCR)
- UniSTS:78672

D15S1477 (e-PCR)
- UniSTS:474482

RH118612 (e-PCR)
- UniSTS:138102

G64212 (e-PCR)
- UniSTS:167641

STS-U20362 (e-PCR)
- UniSTS:63997

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables kinesin binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in cilium assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in cilium assembly	NAS Non-traceable Author Statement more info	PubMed
involved_in inner ear receptor cell stereocilium organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in intraciliary anterograde transport	NAS Non-traceable Author Statement more info	PubMed
involved_in intraciliary transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in kidney development	IBA Inferred from Biological aspect of Ancestor more info
involved_in non-motile cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cilium assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of autophagosome assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of cilium assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to silicon dioxide	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in centriole	IBA Inferred from Biological aspect of Ancestor more info
located_in centriole	IDA Inferred from Direct Assay more info	PubMed
located_in centriole	ISS Inferred from Sequence or Structural Similarity more info
located_in centrosome	IDA Inferred from Direct Assay more info	PubMed
is_active_in ciliary basal body	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary basal body	IDA Inferred from Direct Assay more info	PubMed
located_in ciliary basal body	ISS Inferred from Sequence or Structural Similarity more info
is_active_in ciliary base	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary tip	TAS Traceable Author Statement more info
located_in cilium	IDA Inferred from Direct Assay more info	PubMed
located_in cilium	ISS Inferred from Sequence or Structural Similarity more info
located_in cilium	NAS Non-traceable Author Statement more info	PubMed
located_in cilium	TAS Traceable Author Statement more info
located_in cytosol	TAS Traceable Author Statement more info
part_of intraciliary transport particle B	IPI Inferred from Physical Interaction more info	PubMed
part_of intraciliary transport particle B	ISS Inferred from Sequence or Structural Similarity more info
located_in manchette	ISS Inferred from Sequence or Structural Similarity more info
located_in motile cilium	ISS Inferred from Sequence or Structural Similarity more info
is_active_in non-motile cilium	IBA Inferred from Biological aspect of Ancestor more info
located_in sperm flagellum	ISS Inferred from Sequence or Structural Similarity more info
located_in sperm head-tail coupling apparatus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: intraflagellar transport protein 88 homolog

Names: TPR repeat protein 10; intraflagellar transport 88 homolog; polaris homolog; probe hTg737 (polycystic kidney disease, autosomal recessive); recessive polycystic kidney disease protein Tg737 homolog; testicular tissue protein Li 93; tetratricopeptide repeat domain 10; tetratricopeptide repeat protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001318491.2 → NP_001305420.1 intraflagellar transport protein 88 homolog isoform 3

Status: REVIEWED

Description

Transcript Variant: This variant (3) lacks multiple alternate exons in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (3) with a shorter N-terminus, compared to isoform 1.

Source sequence(s)

AK300769, AL161772, BC030776, BG182322

UniProtKB/TrEMBL

B3KX42

Conserved Domains (6) summary

sd00006
Location:465 → 493

TPR; TPR repeat [structural motif]

cd15832
Location:210 → 241

SNAP; TPR repeat [structural motif]

pfam00515
Location:500 → 524

TPR_1; Tetratricopeptide repeat

pfam13414
Location:464 → 528

TPR_11; TPR repeat

pfam13424
Location:216 → 285

TPR_12; Tetratricopeptide repeat

cl24038
Location:210 → 311

SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family
NM_001318493.2 → NP_001305422.1 intraflagellar transport protein 88 homolog isoform 1

Status: REVIEWED

Description

Transcript Variant: This variant (4) contains an additional segment in the 5' UTR, compared to variant 1, and encodes isoform 1. Variants 1 and 4 encode the same isoform (1).

Source sequence(s)

AK126668, AK308281, AL161772, BC059357, BG182322

Consensus CDS

CCDS31944.1

UniProtKB/TrEMBL

B3KX42

Conserved Domains (2) summary

sd00006
Location:493 → 521

TPR; TPR repeat [structural motif]

cl26002
Location:222 → 730

TPR_11; TPR repeat
NM_001353565.2 → NP_001340494.1 intraflagellar transport protein 88 homolog isoform 1

Status: REVIEWED

Description

Transcript Variant: This variant (6), as well as variants 1, 4, 7, and 8, encodes isoform 1.

Source sequence(s)

AL161772, AL590096

Consensus CDS

CCDS31944.1

UniProtKB/TrEMBL

B3KX42

Conserved Domains (2) summary

sd00006
Location:493 → 521

TPR; TPR repeat [structural motif]

cl26002
Location:222 → 730

TPR_11; TPR repeat
NM_001353566.2 → NP_001340495.1 intraflagellar transport protein 88 homolog isoform 1

Status: REVIEWED

Description

Transcript Variant: This variant (7), as well as variants 1, 4, 6, and 8, encodes isoform 1.

Source sequence(s)

AL161772, AL590096

Consensus CDS

CCDS31944.1

UniProtKB/TrEMBL

B3KX42

Conserved Domains (2) summary

sd00006
Location:493 → 521

TPR; TPR repeat [structural motif]

cl26002
Location:222 → 730

TPR_11; TPR repeat
NM_001353567.2 → NP_001340496.1 intraflagellar transport protein 88 homolog isoform 1

Status: REVIEWED

Description

Transcript Variant: This variant (8), as well as variants 1, 4, 6, and 7, encodes isoform 1.

Source sequence(s)

AL161772, AL590096

Consensus CDS

CCDS31944.1

UniProtKB/TrEMBL

B3KX42

Conserved Domains (2) summary

sd00006
Location:493 → 521

TPR; TPR repeat [structural motif]

cl26002
Location:222 → 730

TPR_11; TPR repeat
NM_001353568.2 → NP_001340497.1 intraflagellar transport protein 88 homolog isoform 2

Status: REVIEWED

Description

Transcript Variant: This variant (9), as well as variant 2, encodes isoform 2.

Source sequence(s)

AL161772, AL590096

Consensus CDS

CCDS31945.1

UniProtKB/Swiss-Prot

A2A491, B4DUS2, Q13099, Q5SZJ6, Q8N719

UniProtKB/TrEMBL

A0A140VJL7, B3KX42

Conserved Domains (2) summary

TIGR02917
Location:213 → 721

PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein

sd00006
Location:484 → 512

TPR; TPR repeat [structural motif]
NM_001353569.2 → NP_001340498.1 intraflagellar transport protein 88 homolog isoform 5

Status: REVIEWED

Description

Transcript Variant: This variant (10), as well as variant 11, encodes isoform 5.

Source sequence(s)

AL161772, AL590096

UniProtKB/TrEMBL

B3KX42

Conserved Domains (3) summary

COG0457
Location:235 → 509

TPR; Tetratricopeptide (TPR) repeat [General function prediction only]

sd00006
Location:459 → 487

TPR; TPR repeat [structural motif]

cl26002
Location:397 → 666

TPR_11; TPR repeat
NM_001353570.2 → NP_001340499.1 intraflagellar transport protein 88 homolog isoform 5

Status: REVIEWED

Description

Transcript Variant: This variant (11), as well as variant 10, encodes isoform 5.

Source sequence(s)

AL161772, AL590096

UniProtKB/TrEMBL

B3KX42

Conserved Domains (3) summary

COG0457
Location:235 → 509

TPR; Tetratricopeptide (TPR) repeat [General function prediction only]

sd00006
Location:459 → 487

TPR; TPR repeat [structural motif]

cl26002
Location:397 → 666

TPR_11; TPR repeat
NM_001353571.2 → NP_001340500.1 intraflagellar transport protein 88 homolog isoform 6

Status: REVIEWED

Source sequence(s)

AL161772, AL590096

UniProtKB/TrEMBL

B3KX42

Conserved Domains (3) summary

smart00028
Location:238 → 265

TPR; Tetratricopeptide repeats

sd00006
Location:450 → 478

TPR; TPR repeat [structural motif]

cl26002
Location:388 → 657

TPR_11; TPR repeat
NM_001353572.2 → NP_001340501.1 intraflagellar transport protein 88 homolog isoform 7

Status: REVIEWED

Source sequence(s)

AL161772, AL590096

UniProtKB/TrEMBL

B3KX42

Conserved Domains (2) summary

sd00006
Location:484 → 512

TPR; TPR repeat [structural motif]

cl26002
Location:213 → 721

TPR_11; TPR repeat
NM_001353573.2 → NP_001340502.1 intraflagellar transport protein 88 homolog isoform 8

Status: REVIEWED

Source sequence(s)

AL161772, AL590096

UniProtKB/TrEMBL

B3KX42

Conserved Domains (2) summary

sd00006
Location:436 → 464

TPR; TPR repeat [structural motif]

cl26002
Location:184 → 664

TPR_11; TPR repeat
NM_001353574.2 → NP_001340503.1 intraflagellar transport protein 88 homolog isoform 9

Status: REVIEWED

Source sequence(s)

AL161772, AL590096

UniProtKB/TrEMBL

B3KX42

Conserved Domains (3) summary

smart00028
Location:219 → 246

TPR; Tetratricopeptide repeats

sd00006
Location:431 → 459

TPR; TPR repeat [structural motif]

cl26002
Location:369 → 638

TPR_11; TPR repeat
NM_001353575.2 → NP_001340504.1 intraflagellar transport protein 88 homolog isoform 10

Status: REVIEWED

Source sequence(s)

AL161772, AL590096

UniProtKB/TrEMBL

B3KX42

Conserved Domains (2) summary

sd00006
Location:465 → 493

TPR; TPR repeat [structural motif]

cl26002
Location:194 → 674

TPR_11; TPR repeat
NM_001353576.2 → NP_001340505.1 intraflagellar transport protein 88 homolog isoform 11

Status: REVIEWED

Description

Transcript Variant: This variant (17), as well as variantm18, encodes isoform 11.

Source sequence(s)

AL161772, AL590096

UniProtKB/TrEMBL

B3KX42

Conserved Domains (3) summary

COG0457
Location:235 → 509

TPR; Tetratricopeptide (TPR) repeat [General function prediction only]

sd00006
Location:459 → 487

TPR; TPR repeat [structural motif]

cl26002
Location:397 → 666

TPR_11; TPR repeat
NM_001353577.2 → NP_001340506.1 intraflagellar transport protein 88 homolog isoform 11

Status: REVIEWED

Description

Transcript Variant: This variant (18), as well as variant 17, encodes isoform 11.

Source sequence(s)

AL161772, AL590096

UniProtKB/TrEMBL

B3KX42

Conserved Domains (3) summary

COG0457
Location:235 → 509

TPR; Tetratricopeptide (TPR) repeat [General function prediction only]

sd00006
Location:459 → 487

TPR; TPR repeat [structural motif]

cl26002
Location:397 → 666

TPR_11; TPR repeat
NM_001353578.2 → NP_001340507.1 intraflagellar transport protein 88 homolog isoform 12

Status: REVIEWED

Source sequence(s)

AL161772, AL590096

UniProtKB/TrEMBL

B3KX42

Conserved Domains (3) summary

smart00028
Location:238 → 265

TPR; Tetratricopeptide repeats

sd00006
Location:450 → 478

TPR; TPR repeat [structural motif]

cl26002
Location:388 → 657

TPR_11; TPR repeat
NM_001353579.2 → NP_001340508.1 intraflagellar transport protein 88 homolog isoform 13

Status: REVIEWED

Source sequence(s)

AL161772, AL590096

Conserved Domains (2) summary

sd00006
Location:273 → 301

TPR; TPR repeat [structural motif]

cl26002
Location:2 → 510

TPR_11; TPR repeat
NM_006531.5 → NP_006522.2 intraflagellar transport protein 88 homolog isoform 2

See identical proteins and their annotated locations for NP_006522.2

Status: REVIEWED

Description

Transcript Variant: This variant (2) lacks multiple alternate exons in the 5' UTR and lacks a portion of the 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1. Variants 2 and 9 both encode the same isoform (2).

Source sequence(s)

AK126668, AK308281, AK310223, AL161772, BC059357, BG182322

Consensus CDS

CCDS31945.1

UniProtKB/Swiss-Prot

A2A491, B4DUS2, Q13099, Q5SZJ6, Q8N719

UniProtKB/TrEMBL

A0A140VJL7, B3KX42

Related

ENSP00000261632.5, ENST00000351808.10

Conserved Domains (2) summary

TIGR02917
Location:213 → 721

PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein

sd00006
Location:484 → 512

TPR; TPR repeat [structural motif]
NM_175605.5 → NP_783195.2 intraflagellar transport protein 88 homolog isoform 1

See identical proteins and their annotated locations for NP_783195.2

Status: REVIEWED

Description

Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1, 4, 6, 7, and 8 all encode the same isoform (1).

Source sequence(s)

AK126668, AL161772, BC030776, BG182322

Consensus CDS

CCDS31944.1

UniProtKB/TrEMBL

B3KX42

Related

ENSP00000323580.6, ENST00000319980.10

Conserved Domains (2) summary

sd00006
Location:493 → 521

TPR; TPR repeat [structural motif]

cl26002
Location:222 → 730

TPR_11; TPR repeat

RNA

NR_134653.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (5) differs at both the 5' and 3' ends, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AK126668, AK310223, AL161772, BC059357, BG182322
NR_148462.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AL161772, AL590096
NR_148463.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AL161772, AL590096
NR_148464.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AL161772, AL590096
NR_148465.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AL161772, AL590096

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000013.11 Reference GRCh38.p14 Primary Assembly

Range

20567157..20691444

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_047430655.1 → XP_047286611.1 intraflagellar transport protein 88 homolog isoform X1

UniProtKB/Swiss-Prot

A2A491, B4DUS2, Q13099, Q5SZJ6, Q8N719

UniProtKB/TrEMBL

A0A140VJL7
XM_017020757.2 → XP_016876246.1 intraflagellar transport protein 88 homolog isoform X1

UniProtKB/Swiss-Prot

A2A491, B4DUS2, Q13099, Q5SZJ6, Q8N719

UniProtKB/TrEMBL

A0A140VJL7, B3KX42

Conserved Domains (2) summary

TIGR02917
Location:213 → 721

PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein

sd00006
Location:484 → 512

TPR; TPR repeat [structural motif]
XM_017020763.2 → XP_016876252.1 intraflagellar transport protein 88 homolog isoform X8

UniProtKB/TrEMBL

B3KX42
XM_017020762.2 → XP_016876251.1 intraflagellar transport protein 88 homolog isoform X6

UniProtKB/TrEMBL

B3KX42
XM_024449413.2 → XP_024305181.1 intraflagellar transport protein 88 homolog isoform X12

UniProtKB/TrEMBL

B3KX42

Conserved Domains (3) summary

smart00028
Location:228 → 255

TPR; Tetratricopeptide repeats

sd00006
Location:440 → 468

TPR; TPR repeat [structural motif]

cl26002
Location:378 → 647

TPR_11; TPR repeat
XM_047430660.1 → XP_047286616.1 intraflagellar transport protein 88 homolog isoform X4
XM_047430670.1 → XP_047286626.1 intraflagellar transport protein 88 homolog isoform X14
XM_047430656.1 → XP_047286612.1 intraflagellar transport protein 88 homolog isoform X2
XM_047430661.1 → XP_047286617.1 intraflagellar transport protein 88 homolog isoform X5
XM_047430671.1 → XP_047286627.1 intraflagellar transport protein 88 homolog isoform X14
XM_047430667.1 → XP_047286623.1 intraflagellar transport protein 88 homolog isoform X11
XM_047430662.1 → XP_047286618.1 intraflagellar transport protein 88 homolog isoform X6
XM_047430659.1 → XP_047286615.1 intraflagellar transport protein 88 homolog isoform X4
XM_047430657.1 → XP_047286613.1 intraflagellar transport protein 88 homolog isoform X2
XM_047430668.1 → XP_047286624.1 intraflagellar transport protein 88 homolog isoform X12
XM_006719870.4 → XP_006719933.1 intraflagellar transport protein 88 homolog isoform X1

See identical proteins and their annotated locations for XP_006719933.1

UniProtKB/Swiss-Prot

A2A491, B4DUS2, Q13099, Q5SZJ6, Q8N719

UniProtKB/TrEMBL

A0A140VJL7, B3KX42

Conserved Domains (2) summary

TIGR02917
Location:213 → 721

PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein

sd00006
Location:484 → 512

TPR; TPR repeat [structural motif]
XM_047430666.1 → XP_047286622.1 intraflagellar transport protein 88 homolog isoform X10
XM_047430665.1 → XP_047286621.1 intraflagellar transport protein 88 homolog isoform X9
XM_047430658.1 → XP_047286614.1 intraflagellar transport protein 88 homolog isoform X3
XM_047430663.1 → XP_047286619.1 intraflagellar transport protein 88 homolog isoform X7
XM_047430674.1 → XP_047286630.1 intraflagellar transport protein 88 homolog isoform X17
XM_047430673.1 → XP_047286629.1 intraflagellar transport protein 88 homolog isoform X16
XM_047430672.1 → XP_047286628.1 intraflagellar transport protein 88 homolog isoform X15
XM_047430675.1 → XP_047286631.1 intraflagellar transport protein 88 homolog isoform X18
XM_047430669.1 → XP_047286625.1 intraflagellar transport protein 88 homolog isoform X13
XM_047430664.1 → XP_047286620.1 intraflagellar transport protein 88 homolog isoform X8
XM_047430676.1 → XP_047286632.1 intraflagellar transport protein 88 homolog isoform X19
XM_017020775.2 → XP_016876264.1 intraflagellar transport protein 88 homolog isoform X20
XM_017020776.2 → XP_016876265.1 intraflagellar transport protein 88 homolog isoform X23
XM_047430679.1 → XP_047286635.1 intraflagellar transport protein 88 homolog isoform X25
XM_047430678.1 → XP_047286634.1 intraflagellar transport protein 88 homolog isoform X24
XM_024449415.2 → XP_024305183.1 intraflagellar transport protein 88 homolog isoform X21

Conserved Domains (2) summary

COG0457
Location:199 → 352

TPR; Tetratricopeptide (TPR) repeat [General function prediction only]

sd00006
Location:247 → 270

TPR; TPR repeat [structural motif]
XM_047430677.1 → XP_047286633.1 intraflagellar transport protein 88 homolog isoform X22

RNA

XR_007063700.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

NC_060937.1 Alternate T2T-CHM13v2.0

Range

19760320..19884580

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054375008.1 → XP_054230983.1 intraflagellar transport protein 88 homolog isoform X1
XM_054375009.1 → XP_054230984.1 intraflagellar transport protein 88 homolog isoform X1
XM_054375020.1 → XP_054230995.1 intraflagellar transport protein 88 homolog isoform X8
XM_054375016.1 → XP_054230991.1 intraflagellar transport protein 88 homolog isoform X6
XM_054375024.1 → XP_054230999.1 intraflagellar transport protein 88 homolog isoform X12
XM_054375014.1 → XP_054230989.1 intraflagellar transport protein 88 homolog isoform X4
XM_054375027.1 → XP_054231002.1 intraflagellar transport protein 88 homolog isoform X14
XM_054375010.1 → XP_054230985.1 intraflagellar transport protein 88 homolog isoform X2
XM_054375015.1 → XP_054230990.1 intraflagellar transport protein 88 homolog isoform X5
XM_054375028.1 → XP_054231003.1 intraflagellar transport protein 88 homolog isoform X14
XM_054375023.1 → XP_054230998.1 intraflagellar transport protein 88 homolog isoform X11
XM_054375017.1 → XP_054230992.1 intraflagellar transport protein 88 homolog isoform X6
XM_054375013.1 → XP_054230988.1 intraflagellar transport protein 88 homolog isoform X4
XM_054375011.1 → XP_054230986.1 intraflagellar transport protein 88 homolog isoform X2
XM_054375025.1 → XP_054231000.1 intraflagellar transport protein 88 homolog isoform X12
XM_054375007.1 → XP_054230982.1 intraflagellar transport protein 88 homolog isoform X1
XM_054375022.1 → XP_054230997.1 intraflagellar transport protein 88 homolog isoform X10
XM_054375021.1 → XP_054230996.1 intraflagellar transport protein 88 homolog isoform X9
XM_054375012.1 → XP_054230987.1 intraflagellar transport protein 88 homolog isoform X3
XM_054375018.1 → XP_054230993.1 intraflagellar transport protein 88 homolog isoform X7
XM_054375031.1 → XP_054231006.1 intraflagellar transport protein 88 homolog isoform X17
XM_054375030.1 → XP_054231005.1 intraflagellar transport protein 88 homolog isoform X16
XM_054375029.1 → XP_054231004.1 intraflagellar transport protein 88 homolog isoform X15
XM_054375032.1 → XP_054231007.1 intraflagellar transport protein 88 homolog isoform X18
XM_054375026.1 → XP_054231001.1 intraflagellar transport protein 88 homolog isoform X13
XM_054375019.1 → XP_054230994.1 intraflagellar transport protein 88 homolog isoform X8
XM_054375033.1 → XP_054231008.1 intraflagellar transport protein 88 homolog isoform X19
XM_054375035.1 → XP_054231010.1 intraflagellar transport protein 88 homolog isoform X26
XM_054375034.1 → XP_054231009.1 intraflagellar transport protein 88 homolog isoform X20
XM_054375038.1 → XP_054231013.1 intraflagellar transport protein 88 homolog isoform X23
XM_054375040.1 → XP_054231015.1 intraflagellar transport protein 88 homolog isoform X25
XM_054375039.1 → XP_054231014.1 intraflagellar transport protein 88 homolog isoform X24
XM_054375037.1 → XP_054231012.1 intraflagellar transport protein 88 homolog isoform X22
XM_054375036.1 → XP_054231011.1 intraflagellar transport protein 88 homolog isoform X21