|
| Status |
Public on Dec 31, 2008 |
| Title |
Curative and beta cell regenerative effects of alpha1 antitrypsin treatment in autoimmune diabetic NOD mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
In this study, we performed the gene expression analysis of the Normal, Diabetic and AAT treated NOD mice to elucidate the transcriptional changes induced by AAT. This will assist in identifying the biological processes / pathways involved in curative mechanism of AAT.
Keywords: alpha1 antitrypsin treatment
|
| |
|
| Overall design |
Duplicate samples of Normal, Diabetic and AAT treated NOD mice were analyzed.
|
| |
|
| Contributor(s) |
Koulmanda M, Strom TB |
| Citation(s) |
18852471 |
| |
| Submission date |
Feb 12, 2008 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Terry B Strom |
| E-mail(s) |
[email protected]
|
| Phone |
6176670853
|
| Organization name |
Beth Israel Deaconess Medical Center
|
| Street address |
77 Avenue Louis Pasteur
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
|
| Samples (6)
|
| GSM265046 |
Fat from NOD mice with blood glucose level of >300mg/dl for 3 consecutive days_DIA1 |
| GSM265047 |
Fat from NOD mice with blood glucose level of >300mg/dl for 3 consecutive days_DIA2 |
| GSM265048 |
Fat from AAT (Alpha-1-antitrypsin) treated NOD mice with stable reversion and insulin independence_AAT1 |
| GSM265049 |
Fat from AAT (Alpha-1-antitrypsin) treated NOD mice with stable reversion and insulin independence_AAT2 |
| GSM265050 |
Fat from 10 weeks normal Glycemic NOD female mice_NOR1 |
| GSM265051 |
Fat from 10 weeks normal Glycemic NOD female mice_NOR2 |
|
| Relations |
| BioProject |
PRJNA108039 |
Less...
More...