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| Status |
Public on Apr 30, 2019 |
| Title |
Effects of rosiglitazone on human omental adipose tissue gene expression |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
The cellular mechanisms by which PPARγ improves metabolism in mature human adipocytes and potential depot differences in its actions are poorly understood.
To assess the global effects of PPARγ activation on human omental gene expression, we conducted microarray analysis of control vs. rosiglitazone-treated omental tissues from human subjects.
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| Overall design |
Adipose tissues fragemnts from 2 independent donors were treated with rosigltiazone (μM) for 7 days. Total RNA was extracted and used for micorray analysis using Affymatrix. Technical duplicates of the first subject were averaged with the values from the second subject prior to statistical analysis.
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| Contributor(s) |
Lee M |
| Citation(s) |
30782959 |
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| Submission date |
Nov 19, 2018 |
| Last update date |
Apr 30, 2019 |
| Contact name |
Mi-Jeong Lee |
| E-mail(s) |
[email protected]
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| Organization name |
Boston University
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| Department |
Medicine
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| Street address |
650 Albany St 810
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| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02118 |
| Country |
USA |
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| Platforms (1) |
| GPL16522 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [HuGene10stv1_Hs_ENTREZG_15.1.0] |
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| Samples (6)
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| GSM3484050 |
donor 983, omentum, vehicle control tech rep1 |
| GSM3484051 |
donor 983, omentum, rosiglitazone tech rep1 |
| GSM3484052 |
donor 983, omentum, vehicle control tech rep2 |
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| Relations |
| BioProject |
PRJNA506075 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE122721_RAW.tar |
23.5 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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