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Status |
Public on Aug 03, 2020 |
Title |
ARID3a expression in human hematopoietic stem cells is associated with distinct gene patterns in aged individuals |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
Aging results in altered gene expression patters in HSCs expressing ARID3A transcirpts, with a number of genes downregulated in aged donor ARID3a+ HSCs compared to young donor ARID3a+ HSCs
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Overall design |
scRNA-seq of isolated peripheral blood HSCs from young and aged donors.
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Contributor(s) |
Webb C, Ratliff M |
Citation(s) |
32905435 |
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Submission date |
Oct 07, 2019 |
Last update date |
Sep 18, 2020 |
Contact name |
Michelle L Ratliff |
E-mail(s) |
[email protected]
|
Phone |
2527443127
|
Organization name |
East Carolina University
|
Department |
Microbiology and Immunology
|
Street address |
600 Moye Blvd, 132 Biotechnology Building
|
City |
Greenville |
State/province |
NC |
ZIP/Postal code |
27834 |
Country |
USA |
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Platforms (1) |
GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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Samples (730)
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Relations |
BioProject |
PRJNA576353 |
SRA |
SRP224720 |