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Series GSE16028 Query DataSets for GSE16028
Status Public on May 09, 2009
Title Longitudinal study of gene expression in healthy individuals
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The gene expression profile of blood drawn from healthy individuals was studied over a period of six months, at five time points. The gene expression profiles appeared to be constant over one month and to slightly vary over three months. A small proportion of genes were found to be differentially regulated according to gender. Differential gene regulation by age (in subjects 25–55 years of age versus subjects > 55 years of age) was not observed.
 
Overall design Healthy subjects were enrolled at a single site, their health status was determined by medical history, physical examination, and standard laboratory test values. Venous blood was drawn in the morning, from fasted subjects at five time points (Day1, Day14, Day28, Day 90 and Day 180). Blood was collected into PAXgene tubes (Becton-Dickinson Diagnostics; Hombrechtikon, Switzerland).
 
Contributor(s) Karlovich C, Duchateau-Nguyen G, Johnson A, McLoughlin P, Navarro M, Fleurbaey C, Steiner L, Tessier M, Nguyen T, Wilhelm-Seiler M, Caulfield J
Citation(s) 19500411
Submission date May 08, 2009
Last update date Mar 25, 2019
Contact name Guillemette Duchateau-Nguyen
E-mail(s) [email protected]
Organization name F.Hoffmann-La Roche AG
Department Pharma Research and Early Development
Lab Translational Technologies and Bioinformatics
Street address Building 93
City Basel
ZIP/Postal code 4070
Country Switzerland
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (109)
GSM401059 Blood sample from patient 106 at Day 1
GSM401060 Blood sample from patient 106 at Day 14
GSM401061 Blood sample from patient 106 at Day 28
Relations
BioProject PRJNA115381

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE16028_RAW.tar 462.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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