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| Status |
Public on Mar 14, 2023 |
| Title |
Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Balanced immune responses in airways of patients with asthma are crucial to succesful clearance of viral infection and proper asthma control.
We used microarrays to detail the global programme of gene expression data from bronchial brushings from control individuals and patients with asthma after rhinovirus infection in vivo.
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| Overall design |
Bronchial brushings from control individuals and patients with asthma around two weeks before (day -14) and four days after (day 4) experimental in vivo rhinovirus infection were used for RNA isolation and hybrydyzation with Affymetric microarrays.
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| Contributor(s) |
Johnston S, Jackson D, Edwards M, Kebadze T, Williamson R, Sokolowska M |
| Citation(s) |
37087523 |
| |
| Submission date |
Oct 11, 2021 |
| Last update date |
May 08, 2023 |
| Contact name |
Ge Tan |
| E-mail(s) |
[email protected]
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| Organization name |
University of Zurich
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| Department |
Functional Genomics Center Zurich
|
| Street address |
Winterthurerstrasse 190
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| City |
Zurich |
| ZIP/Postal code |
8057 |
| Country |
Switzerland |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (48)
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| Relations |
| BioProject |
PRJNA770339 |
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