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Status |
Public on Aug 24, 2011 |
Title |
Role and function of STAT5 in BCR-ABL1 driven pre-B cells |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
|
Summary |
In order to investigate the function of STAT5 in ALL, we isolated bone marrow cells from STAT5 fl/fl mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven pre-B cells were transformed either with CRE-GFP or empty vector control (GFP) and subjected to gene expression analysis.
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Overall design |
Three days post transduction, total RNA of GFP positive sorted cells was extracted and subjected to gene expression analysis.
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Contributor(s) |
Ramezani-Rad P |
Citation(s) |
21911423, 23852341 |
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Submission date |
Oct 20, 2010 |
Last update date |
Mar 04, 2019 |
Contact name |
Markus Müschen |
E-mail(s) |
[email protected]
|
Phone |
+ 1 323 361 5592
|
Fax |
+1 323 361 1516
|
URL |
http://www.lymphocytes.de/
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Organization name |
University of Southern California
|
Department |
Childrens Hospital Los Angeles
|
Lab |
Müschen Lab
|
Street address |
4650 Sunset Blvd
|
City |
Los Angeles |
State/province |
CA |
ZIP/Postal code |
90027 |
Country |
USA |
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Platforms (1) |
GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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Samples (6)
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GSM610862 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell cre chip1 |
GSM610863 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell cre chip2 |
GSM610864 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell cre chip3 |
GSM610865 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell pMIG chip1 |
GSM610866 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell pMIG chip2 |
GSM610867 |
Stat5 deletion in BCR-ABL1 transformed pre-B cell pMIG chip3 |
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Relations |
BioProject |
PRJNA132193 |