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| Status |
Public on Mar 02, 2013 |
| Title |
Progressive epigenetic changes in milk protein gene loci during functional differentiation of the mammary gland: ChIP-Seq part I |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
The role of chromatin in mammary gland development and differentiation has not been defined. Here we have studied the changes in chromatin conformation in the mammary gland during the lactation cycle at milk protein gene loci, whose gene expression marks functional differentiation of the mammary gland
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| Overall design |
histone modification patterns were studied using ChIP-seq in Lactating (day 8) mammary gland tissue, Mammary epithelial cells Isolated from 12 week virgin (diestrus) mammary gland tissue, and liver from 8 day lactating female.
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| Contributor(s) |
Rijnkels M, Zadrowski CF, Hernandez J, Potluri V, Lin A, Lemay D, Wang L, Li W |
| Citation(s) |
23301053, 24086428 |
| |
| Submission date |
Nov 03, 2010 |
| Last update date |
Feb 05, 2020 |
| Contact name |
LIGUO WANG |
| E-mail(s) |
[email protected]
|
| Organization name |
Mayo Clinic
|
| Department |
Division of Computational Biology
|
| Street address |
200 1st St SW
|
| City |
Rochester |
| State/province |
MN |
| ZIP/Postal code |
55905 |
| Country |
USA |
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| Platforms (1) |
| GPL9250 |
Illumina Genome Analyzer II (Mus musculus) |
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| Samples (10)
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| Relations |
| SRA |
SRP004432 |
| BioProject |
PRJNA134495 |
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