|
| Status |
Public on Jan 27, 2011 |
| Title |
Expression data from human fibroblasts 6 and 12 hours after 8-oxoguanine treatment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
8-oxoguanine is excised from DNA by 8-oxoguanine DNA glycosylase-1 during DNA base excision repair.
We used microarrays to gain insight into the potential biological function of the excised, free 8-oxoguanine base.
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| |
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| Overall design |
MRC5, human diploid fibroblasts were exposed to 8-oxoguanine and changes in gene expression compared to mock control were analyzed 6 hours after exposure.
MRC5, human diploid fibroblasts were exposed to 8-oxoguanine and changes in gene expression compared to mock control were analyzed 12 hours after exposure.
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| |
|
| Contributor(s) |
German P, Hajas G, Szaniszlo P, Boldogh I |
| Citation(s) |
22568941, 25250913 |
| |
| Submission date |
Jan 24, 2011 |
| Last update date |
Jan 28, 2020 |
| Contact name |
Istvan Boldogh |
| E-mail(s) |
[email protected]
|
| Organization name |
University of Texas Medical Branch at Galveston
|
| Street address |
301 University Blvd.
|
| City |
Galveston |
| State/province |
TX |
| ZIP/Postal code |
77555 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL201 |
[HG-Focus] Affymetrix Human HG-Focus Target Array |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
|
| Samples (8)
|
| GSM659544 |
P25BN13282 8oxoG, technical rep.-extract 2 |
| GSM659545 |
P25CN13282 8oxoG, technical rep.-extract 3 |
| GSM659546 |
P26AN13282 mock, technical rep.-extract 1 |
| GSM659547 |
P26BN13282 mock, technical rep.-extract 2 |
| GSM659548 |
P26CN13282 mock, technical rep.-extract 3 |
|
| Relations |
| BioProject |
PRJNA136005 |
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