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Series GSE31996 Query DataSets for GSE31996
Status Public on Oct 01, 2014
Title Gene Expression data from Mouse C57bl6 Bone marrow derived macrophages infected by the promastigote form of Leishmania major parasite (P) or Killed parasite (Kp) during a time course of infection [C57bl6]
Organism Mus musculus
Experiment type Expression profiling by array
Summary We analyzed the transcriptional signatures of mouse bone marrow-derived macrophages (BMDM) at different times after infection with promastigotes of the protozoan parasite Leishmania major.
GeneChip Mouse Gene 1.0 ST arrays were used to analyse global changes in gene transcripts to generate a pool of genes that was statistically significant (p-value < 0.05) and a fold change cut-off of 1.5 in at least one of the five infected samples versus non-infected samples.
 
Overall design Three independent biological replicates for each biological condition (Non infected "NI", infected with lived parasite "P" or "heat inactivated parasite "Kp") at 1h (T1), 3(T3), 6(T6), 12 (T12) and 24hours (T24) were performed. The Non infected (NI) at 0 hour (T0) biological condition were used as an additional control.
 
Contributor(s) Rabhi I, Rabhi S, Ben-Othman R, Rasche A, Daskalaki A, Regnault B, Guizani-Tabbane L
Citation(s) 24148319, 37187743
Submission date Sep 08, 2011
Last update date Aug 04, 2023
Contact name lamia Guizani-Tabbane
E-mail(s) [email protected]
Phone 0021698311019
Organization name Insitut Pasteur de Tunis
Department Immunopathology
Street address 13, Place Pasteur BP74. Tunis-Belvedere
City Tunis
ZIP/Postal code 1002
Country Tunisia
 
Platforms (1)
GPL6246 [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Samples (48)
GSM792518 Non Infected C57bl6 macrophages at T0, rep1
GSM792519 Non Infected C57bl6 macrophages at T0, rep2
GSM792520 Non Infected C57bl6 macrophages at T0, rep3
This SubSeries is part of SuperSeries:
GSE31997 Gene Expression data from mouse bone marrow derived macrophages infected by the promastigote form of Leishmania major parasite (P) or Killed parasite (Kp) during a time course of infection
Relations
BioProject PRJNA155267

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE31996_C57bl6_normalized_data.txt.gz 1.2 Mb (ftp)(http) TXT
GSE31996_RAW.tar 172.9 Mb (http)(custom) TAR (of CEL)
GSE31996_data_processing.txt.gz 2.8 Kb (ftp)(http) TXT
Processed data are available on Series record
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