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| Status |
Public on Dec 13, 2011 |
| Title |
Gene expression profiles along the tonotopic axis of the mouse cochlea during neonatal development |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The cochlear duct is tonotopically organized, such that the basal cochlea responds more sensitively to high frequency sounds and the apical cochlea to low frequency sounds. In effort to understand how the tonotopic organization is established in mammals, we searched for genes that are differentially expressed along the tonotopic axis during neonatal development.
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| Overall design |
Eighty temporal bones were dissected from C57BL/6 mice at P0 and P8. Two biological replicates were performed. The cochlear tissues were divided into three equal pieces representing the basal, middle and apical turns, and pooled separately. Twelve total RNA from the pooled samples were applied to 12 GeneChips.
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| Contributor(s) |
Son EJ, Wu L, Yoon H, Kim S, Kim H, Bok J |
| Citation(s) |
22808246 |
| |
| Submission date |
Dec 06, 2011 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Heejei Yoon |
| E-mail(s) |
[email protected]
|
| Phone |
2-2228-1657
|
| Organization name |
Yonsei University
|
| Department |
Anatomy
|
| Lab |
Developmental Biology
|
| Street address |
134 Shinchondong, Seodaemoongu
|
| City |
Seoul |
| ZIP/Postal code |
120-749 |
| Country |
South Korea |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
|
| GSM843603 |
Basal cochlea at postnatal day 0 [P0-Base_2011] |
| GSM843604 |
Middle cochlea at postnatal day 0 [P0-Mid_2011] |
| GSM843605 |
Apical cochlea at postnatal day 0 [P0-Apex_2011] |
| GSM843606 |
Basal cochlea at postnatal day 8 [P8-Base_2011] |
| GSM843607 |
Middle cochlea at postnatal day 8 [P8-Mid_2011] |
| GSM843608 |
Apical cochlea at postnatal day 8 [P8-Apex_2011] |
| GSM920936 |
Basal cochlea at postnatal day 0 [P0-Base_2012] |
| GSM920937 |
Middle cochlea at postnatal day 0 [P0-Mid_2012] |
| GSM920938 |
Apical cochlea at postnatal day 0 [P0-Apex_2012] |
| GSM920939 |
Basal cochlea at postnatal day 8 [P8-Base_2012] |
| GSM920940 |
Middle cochlea at postnatal day 8 [P8-Mid_2012] |
| GSM920941 |
Apical cochlea at postnatal day 8 [P8-Apex_2012] |
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| Relations |
| BioProject |
PRJNA149701 |
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