|
Status |
Public on Jun 03, 2013 |
Title |
Role and function of Pten in BCR-ABL1 driven pre-B cells |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
|
Summary |
In order to investigate the function of Pten in ALL, we isolated bone marrow cells from Pten fl/fl mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven pre-B cells were transformed either with CRE-ERT2 or ERT2 (PMIP) and after 2 days of treatment with 4OH-Tamoxifen (0.5 micromolar) subjected to gene expression analysis.
|
|
|
Overall design |
Two days after treatment with 4OH-Tamoxifen (0.5 micromolar) total RNA of Puromycin resistant cells was extracted and subjected to gene expression analysis.
|
|
|
Contributor(s) |
shojaee s |
Citation(s) |
26974310 |
|
Submission date |
Jan 03, 2012 |
Last update date |
Jun 26, 2019 |
Contact name |
Markus Müschen |
E-mail(s) |
[email protected]
|
Phone |
+ 1 323 361 5592
|
Fax |
+1 323 361 1516
|
URL |
http://www.lymphocytes.de/
|
Organization name |
University of Southern California
|
Department |
Childrens Hospital Los Angeles
|
Lab |
Müschen Lab
|
Street address |
4650 Sunset Blvd
|
City |
Los Angeles |
State/province |
CA |
ZIP/Postal code |
90027 |
Country |
USA |
|
|
Platforms (1) |
GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
Samples (6)
|
|
Relations |
BioProject |
PRJNA150237 |