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Status |
Public on Oct 01, 2012 |
Title |
Control of RelB during dendritic cell activation integrates canonical and non-canonical NFkB pathways |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Dendritic cells (DC) play central roles in coordinating appropriate immune responses to pathogens. In the present study, the genes regulated by NFkB activators, RelB and cRel, in PAMP-induced bone marrow dendritic cells (BMDCs) activation was examined.
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Overall design |
Total RNA extracted from WT, relb-/-, crel-/-relb-/- bone marrow derived dendritic cells (BMDCs) were subjected to stimulation with CpG or Pam3CSK4.
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Contributor(s) |
Shih VF, Hoffmann A |
Citation(s) |
23086447 |
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Submission date |
Jan 10, 2012 |
Last update date |
Jun 14, 2018 |
Contact name |
Vincent Feng-Sheng Shih |
Organization name |
UCSD
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Department |
Chemistry and Biochemistry
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Lab |
UCSD Signaling Systems Laboratory
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Street address |
UCSD m/c 0375, NSB 3318 9500, Gilman Dr.
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City |
La Jolla |
State/province |
CA |
ZIP/Postal code |
92093-0375 |
Country |
USA |
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Platforms (1) |
GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
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Samples (21)
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Relations |
BioProject |
PRJNA151093 |