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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Oct 17, 2012 |
| Title |
Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Analysis of MDSC subsets from naive blood and RMA-S blood and RMA-S tumor, respectively. Tumor-infiltrating MO-MDSCs changed their expression pattern compared to blood and exhibited high levels of chemokines
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| Overall design |
Total RNA obtained from PMN-MDSCs and MO-MDSCs from naive blood or from blood and tumor of RMA-S bearing mice
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| Contributor(s) |
Schlecker E, Stojanovic A, Eisen C, Quack C, Falk C, Umansky V, Cerwenka A |
| Citation(s) |
23152559 |
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| Submission date |
Oct 16, 2012 |
| Last update date |
Jan 18, 2013 |
| Contact name |
Christian Eisen |
| E-mail(s) |
[email protected]
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| Organization name |
German Cancer Research Center
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| Street address |
Im Neuenheimer Feld 280
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| City |
Heidelberg |
| ZIP/Postal code |
69120 |
| Country |
Germany |
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| Platforms (1) |
| GPL6105 |
Illumina mouse-6 v1.1 expression beadchip |
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| Samples (18)
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| GSM1020253 |
MO-MDSC naive blood, repl.1 |
| GSM1020254 |
MO-MDSC naive blood, repl.2 |
| GSM1020255 |
MO-MDSC naive blood, repl.3 |
| GSM1020256 |
PMN-MDSC RMA-S blood, repl. 1 |
| GSM1020257 |
PMN-MDSC RMA-S blood, repl. 2 |
| GSM1020258 |
PMN-MDSC RMA-S blood, repl. 3 |
| GSM1020259 |
MO-MDSC RMA-S blood, repl. 1 |
| GSM1020260 |
MO-MDSC RMA-S blood, repl. 2 |
| GSM1020261 |
MO-MDSC RMA-S blood, repl. 3 |
| GSM1020262 |
PMN-MDSC RMA-S tumor, repl.1 |
| GSM1020263 |
PMN-MDSC RMA-S tumor, repl.2 |
| GSM1020264 |
PMN-MDSC RMA-S tumor, repl.3 |
| GSM1020265 |
MO-MDSC RMA-S tumor, repl.1 |
| GSM1020266 |
MO-MDSC RMA-S tumor, repl.2 |
| GSM1020267 |
MO-MDSC RMA-S tumor, repl.3 |
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| Relations |
| BioProject |
PRJNA177723 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE41620_RAW.tar |
10.2 Mb |
(http)(custom) |
TAR (of CSV) |
| GSE41620_normalized.txt.gz |
10.1 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
| Processed data are available on Series record |
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