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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jun 01, 2013 |
| Title |
Genome-wide analysis of the effects of propranolol on angiosarcoma tumor cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Analysis of the effects of 4 hr and 24 hr propranolol treatment on gene expression of SVR mouse angiosarcoma cells. The hypothesis tested in the present study was that inhibiton of beta adrenergic receptor signaling could ablate the oncogenic properties of angiosarcoma cells. Results provide important information of the response of angiosarcoma cells to ablated beta adrenergic receptor signaling.
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| Overall design |
The total RNA was obtained from mouse angiosarcoma cells cultured in monolayer at 0, 4, and 24 hrs of 50 micromolar propranolol treatment. Illumina microarrays were performed to determine the whole genome expression changes following treatment.
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| Contributor(s) |
Bryan BA, Mitchell DD |
| Citation(s) |
23555867 |
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| Submission date |
Nov 27, 2012 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Brad Allen Bryan |
| E-mail(s) |
[email protected]
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| Organization name |
Texas Tech University Health Sciences Center
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| Department |
Biomedical Sciences
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| Street address |
5001 El Paso Drive
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| City |
El Paso |
| State/province |
Texas |
| ZIP/Postal code |
79905 |
| Country |
USA |
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| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
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| Samples (9)
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| GSM1044355 |
SVR, 50 micromolar propranolol, 4h (rep 1) |
| GSM1044356 |
SVR, 50 micromolar propranolol, 4h (rep 2) |
| GSM1044357 |
SVR, 50 micromolar propranolol, 4h (rep 3) |
| GSM1044358 |
SVR, 50 micromolar propranolol, 24h (rep 1) |
| GSM1044359 |
SVR, 50 micromolar propranolol, 24h (rep 2) |
| GSM1044360 |
SVR, 50 micromolar propranolol, 24h (rep 3) |
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| Relations |
| BioProject |
PRJNA182219 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE42534_RAW.tar |
3.1 Mb |
(http)(custom) |
TAR |
| GSE42534_non-normalized.txt.gz |
2.7 Mb |
(ftp)(http) |
TXT |
| GSE42534_normalized.txt.gz |
2.7 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
| Processed data are available on Series record |
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