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| Status |
Public on Feb 05, 2013 |
| Title |
Genome-wide analysis of gene expression profile of Intestinal (COLON) Tumors from APCmin/+/VP16LXRa vs APCmin/+/VP16 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Changes in gene expression profile of intestinal (COLON) Tumors from APCmin/+/VP16LXRa vs APCmin/+/VP16. The hypothesis tested in the present study was that LXRa overexpression influence cancer growth modulating lipid metabolism in cancer cells. Results provide the information that LXRa induces expression of genes encoding proteins able to regulate cholesterol efflux.
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| Overall design |
Total RNA obtained from colonic tumors from APCmin/+/VP16LXRa mice was compared to total RNA extracted from APCmin/+/VP16 mice.
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| Contributor(s) |
Bovenga F, Andria D |
| Citation(s) |
23419360 |
| |
| Submission date |
Feb 05, 2013 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Antonio Moschetta |
| Organization name |
University of Bari & Consorzio Mario Negri Sud
|
| Street address |
Via Nazionale 8A
|
| City |
Santa Maria Imbaro |
| ZIP/Postal code |
66030 |
| Country |
Italy |
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| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
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| Samples (8)
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| This SubSeries is part of SuperSeries: |
| GSE44073 |
Liver X Receptors play an antitumoral role in the intestine |
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| Relations |
| BioProject |
PRJNA188556 |
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