|
| Status |
Public on Apr 07, 2014 |
| Title |
Gene expression in Arabidopsis ddm1 mutants with high levels of Transposable Element activity |
| Organism |
Arabidopsis thaliana |
| Experiment type |
Expression profiling by array
|
| Summary |
Background: Transposable elements are known to influence the regulation of some genes. We aimed to determine which genes show altered gene expression when transposable elements are epigenetically activated.
Results: We find over 2000 genes with altered steady-state expression levels in ddm1 mutants. Some of these genes are influenced by neighboring transposable element fragments, while other genes are targeted by transposable element derived 21 nucleotide siRNAs.
Conclusion: The regulation of the genic portion of the Arabidopsis genome is heavily influenced by the epigenetic regulation of transposable elements. The regulation of genes by transposable elements can occur through multiple mechanisms.
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| |
|
| Overall design |
Three biological replicates for two genotypes
|
| |
|
| Contributor(s) |
Slotkin RK, Panda K |
| Citation(s) |
23863322 |
| |
| Submission date |
Apr 15, 2013 |
| Last update date |
Jun 12, 2017 |
| Contact name |
Richard Keith Slotkin |
| E-mail(s) |
[email protected]
|
| Organization name |
The Ohio State University
|
| Department |
Molecular Genetics
|
| Lab |
Slotkin Laboratory
|
| Street address |
318 West 12th Ave.
|
| City |
Columbus |
| State/province |
OH |
| ZIP/Postal code |
43210 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL198 |
[ATH1-121501] Affymetrix Arabidopsis ATH1 Genome Array |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA197304 |
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