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| Status |
Public on Jul 22, 2006 |
| Title |
Gene expression profiling of whole epididymis in embryonic (gestational day 12, 14, 16 & 18) and postnatal day 2 mice. (GUDMAP Series ID: 4) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The overall objective of this proposal is to map the temporal and spatial dynamics of gene expression in the fetal mouse testis at key developmental timepoints. Urogenital tract malformations are the most common birth defects in males and their incidence together with other male reproductive health concerns such as reduced fertility and testicular cancer are reportedly on the rise in the human population. To better understand the impact of genetic factors and environmental influences on testicular development, it is important to first understand normal gene expression patterns and signaling cascades within the fetal testis during development. The goal of this study is to identify cell-specific genes that can be used as biomarkers for key differentiation events.
Keywords: developmental time course
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| Overall design |
Day to day comparison in whole epididymus throughout development with triplicates at each time point. Each sample is a pair of epididymus from a single animal and each animal is taken from a different dam.
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| Contributor(s) |
Gaido K, Lehmann K |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jul 18, 2006 |
| Last update date |
Feb 11, 2019 |
| Contact name |
GUDMAP Developers |
| E-mail(s) |
[email protected]
|
| Phone |
+44 131 651 8500
|
| Organization name |
IGMM MRC Human Genetics Unit
|
| Lab |
GUDMAP Database Group
|
| Street address |
Crewe Road
|
| City |
Edinburgh |
| ZIP/Postal code |
EH4 2XU |
| Country |
United Kingdom |
| |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (16)
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| GSM120825 |
Gaido_Epididymus_gd18_4_25May2006 |
| GSM120826 |
Gaido_Epididymus_gd18_5_25May2006 |
| GSM120827 |
Gaido_Epididymus_gd18_6_25May2006 |
| GSM120828 |
Gaido_Epididymus_gd16_7_25May2006 |
| GSM120829 |
Gaido_Epididymus_gd16_8_25May2006 |
| GSM120830 |
Gaido_Epididymus_gd16_9_25May2006 |
| GSM120831 |
Gaido_Epididymus_gd14_10_25May2006 |
| GSM120832 |
Gaido_Epididymus_gd14_11_25May2006 |
| GSM120833 |
Gaido_Epididymus_gd14_12_25May2006 |
| GSM120834 |
Gaido_Epididymus_gd12_13_25May2006 |
| GSM120835 |
Gaido_Epididymus_gd12_14_25May2006 |
| GSM120836 |
Gaido_Epididymus_gd12_15_25May2006 |
| GSM120837 |
Gaido_WholeLitterReference_pnd0.5_16_25May2006 |
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| Relations |
| BioProject |
PRJNA96349 |
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