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| Status |
Public on Aug 24, 2007 |
| Title |
Genetic changes in the evolution of multidrug resistance for cultured human ovarian cancer cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Gene expression profiles were assessed for vincristine-sensitive parental ovarian tumor cell line (SKOV3) and its highly vincristine-resistant derivative (SKVCR 2.0)
Keywords: vincristine, drug resistance, ovarian, SKOV3, MDR
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| |
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| Overall design |
Duplicate gene expression microarray experiments were undertaken for each of SKOV3 and SKVCR 2.0. Comparative analysis between these two groups defined genes activated in vincristine resistance
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| |
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| Contributor(s) |
Buys TP, Chari R, Lee EH, Zhang M, MacAulay C, Lam S, Lam WL, Ling V |
| Citation(s) |
17726699, 25560085 |
| |
| Submission date |
Apr 19, 2007 |
| Last update date |
Jun 27, 2019 |
| Contact name |
T Buys |
| Organization name |
British Columbia Cancer Research Centre
|
| Department |
Cancer Genetics and Developmental Biology
|
| Lab |
Wan Lam Lab
|
| Street address |
675 W.10th Avenue
|
| City |
Vancouver |
| State/province |
BC |
| ZIP/Postal code |
V5Z 1L3 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA100375 |
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