|
| Status |
Public on Feb 23, 2016 |
| Title |
Derivation, characterization, and neuronal differentiation of integration-free induced pluripotent stem cell lines from Parkinsons disease patients carrying SNCA, LRRK2, PARK2, and GBA mutations |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of whole genome expression in control and patients with Parkinsons disease iPSC lines. The hypothesis tested in present study was that deficient GBA, SNCA, LRRK2 and PARKIN expression can be used for disease modeling by their affects on multiple pathways. These results provide information on relationship between PD genes and mitochondria related gene expression.
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| |
|
| Overall design |
Total RNA obtained from patient iPSC line compare to control iPSC line
|
| |
|
| Contributor(s) |
Zeng X |
| Citation(s) |
27191603 |
| |
| Submission date |
Feb 22, 2016 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Ying Pei |
| Organization name |
Buck Institute
|
| Street address |
8001 redwood blvd
|
| City |
novato |
| State/province |
ca |
| ZIP/Postal code |
94945 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA312783 |
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