|
| Status |
Public on Mar 23, 2017 |
| Title |
Comparison of gene expression in control bam-Gal4 and control undriven tbrd-2RNAi Drosophila testes with tbrd-2 knockdown testes |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by array
|
| Summary |
Gene expression is tightly linked to histone acetylation on lysine residues that can be recognized by bromodomains. The testis-specific bromodomain protein tBRD-2 is essential for male fertility, interacts with tBRD-1 and might act as a co-factor of testis-specifc TAFs. Here, we perform microarray analyses and demonstrate that tBRD-2 selectively controls gene expression in male germ cells.
|
| |
|
| Overall design |
Testes were dissected from 0-2 day old Drosophila males. The control samples were bam-Gal4 and undriven tbrd-2 RNAi. In addition testes from tbrd-2 knockdown males were used.
|
| |
|
| Contributor(s) |
Rathke C, Bartkuhn M |
| Citation(s) |
28235844 |
| |
| Submission date |
May 02, 2016 |
| Last update date |
Jul 11, 2019 |
| Contact name |
Marek Bartkuhn |
| E-mail(s) |
[email protected]
|
| Organization name |
Justus-Liebig-University Giessen
|
| Department |
Biomedical Informatics and Systems Medicine
|
| Street address |
Aulweg 132
|
| City |
Giessen |
| State/province |
Hessen |
| ZIP/Postal code |
35392 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL1322 |
[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA320296 |
Less...
More...