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Benign neoplasm of pharynx

MedGen UID:
102296
•Concept ID:
C0153940
•
Neoplastic Process
Synonyms: Benign Neoplasm of Pharynx; benign neoplasm of pharynx; Benign Neoplasm of the Pharynx; benign neoplasm of the pharynx; Benign Pharyngeal Neoplasm; benign pharyngeal neoplasm; Benign Pharyngeal Tumor; benign pharyngeal tumor; benign pharyngeal tumour; Benign Pharynx Neoplasm; benign pharynx neoplasm; Benign Pharynx Tumor; benign pharynx tumor; benign pharynx tumour; Benign Tumor of Pharynx; benign tumor of pharynx; Benign Tumor of the Pharynx; benign tumor of the pharynx; benign tumour of pharynx; benign tumour of the pharynx; Pharyngeal Neoplasm Benign; pharyngeal neoplasm benign; pharynx benign neoplasm
SNOMED CT: Benign neoplasm of pharynx (92293007)
 
Monarch Initiative: MONDO:0021523

Definition

A neoplasm that arises from the pharynx and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Machiels JP, René Leemans C, Golusinski W, Grau C, Licitra L, Gregoire V; EHNS Executive Board. Electronic address: [email protected]; ESMO Guidelines Committee. Electronic address: [email protected]; ESTRO Executive Board. Electronic address: [email protected]
Ann Oncol 2020 Nov;31(11):1462-1475. Epub 2020 Oct 23 doi: 10.1016/j.annonc.2020.07.011. PMID: 33239190
Head and neck cancer prevention: from primary prevention to impact of clinicians on reducing burden.
Hashim D, Genden E, Posner M, Hashibe M, Boffetta P
Ann Oncol 2019 May 1;30(5):744-756. doi: 10.1093/annonc/mdz084. PMID: 30840052Free PMC Article
Clinical Practice Guideline: Evaluation of the Neck Mass in Adults.
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406

Recent clinical studies

Etiology

Tonsillectomy and the incidence of various types of cancer.
Holló G
Immunol Res 2021 Dec;69(6):467-470. Epub 2021 Sep 15 doi: 10.1007/s12026-021-09230-3. PMID: 34523058Free PMC Article
Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Machiels JP, René Leemans C, Golusinski W, Grau C, Licitra L, Gregoire V; EHNS Executive Board. Electronic address: [email protected]; ESMO Guidelines Committee. Electronic address: [email protected]; ESTRO Executive Board. Electronic address: [email protected]
Ann Oncol 2020 Nov;31(11):1462-1475. Epub 2020 Oct 23 doi: 10.1016/j.annonc.2020.07.011. PMID: 33239190
Target volume selection and delineation (T and N) for primary radiation treatment of oral cavity, oropharyngeal, hypopharyngeal and laryngeal squamous cell carcinoma.
Grégoire V, Grau C, Lapeyre M, Maingon P
Oral Oncol 2018 Dec;87:131-137. Epub 2018 Nov 3 doi: 10.1016/j.oraloncology.2018.10.034. PMID: 30527228
Association between helicobacter pylori infection and carcinoma of the larynx or pharynx.
Zhou J, Zhang D, Yang Y, Zhou L, Tao L
Head Neck 2016 Apr;38 Suppl 1:E2291-6. Epub 2015 Aug 28 doi: 10.1002/hed.24214. PMID: 26316145
Carcinoma of the tonsil; a review of treatment and its results in a group of 90 cases.
WALKER JH, SCHULZ MD
Radiology 1947 Aug;49(2):162-8. doi: 10.1148/49.2.162. PMID: 20256673

Diagnosis

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Diagnosis and treatment of congenital nasal glioma.
Baldovin M, Saratziotis A, Munari S, Emanuelli E
BMJ Case Rep 2021 Apr 13;14(4) doi: 10.1136/bcr-2021-242138. PMID: 33849883Free PMC Article
Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Machiels JP, René Leemans C, Golusinski W, Grau C, Licitra L, Gregoire V; EHNS Executive Board. Electronic address: [email protected]; ESMO Guidelines Committee. Electronic address: [email protected]; ESTRO Executive Board. Electronic address: [email protected]
Ann Oncol 2020 Nov;31(11):1462-1475. Epub 2020 Oct 23 doi: 10.1016/j.annonc.2020.07.011. PMID: 33239190
Association between helicobacter pylori infection and carcinoma of the larynx or pharynx.
Zhou J, Zhang D, Yang Y, Zhou L, Tao L
Head Neck 2016 Apr;38 Suppl 1:E2291-6. Epub 2015 Aug 28 doi: 10.1002/hed.24214. PMID: 26316145
The pharynx: examination of an area too often ignored during upper endoscopy.
Emura F, Baron TH, Gralnek IM
Gastrointest Endosc 2013 Jul;78(1):143-9. Epub 2013 Apr 11 doi: 10.1016/j.gie.2013.02.021. PMID: 23582474

Therapy

Tonsillectomy and the incidence of various types of cancer.
Holló G
Immunol Res 2021 Dec;69(6):467-470. Epub 2021 Sep 15 doi: 10.1007/s12026-021-09230-3. PMID: 34523058Free PMC Article
Clinical practice guideline for the prevention of oral and oropharyngeal mucositis in pediatric cancer and hematopoietic stem cell transplant patients: 2021 update.
Patel P, Robinson PD, Baggott C, Gibson P, Ljungman G, Massey N, Ottaviani G, Phillips R, Revon-Rivière G, Treister N, White M, Cabral S, Dupuis L, Sung L
Eur J Cancer 2021 Sep;154:92-101. Epub 2021 Jul 9 doi: 10.1016/j.ejca.2021.05.013. PMID: 34252760
Association between helicobacter pylori infection and carcinoma of the larynx or pharynx.
Zhou J, Zhang D, Yang Y, Zhou L, Tao L
Head Neck 2016 Apr;38 Suppl 1:E2291-6. Epub 2015 Aug 28 doi: 10.1002/hed.24214. PMID: 26316145
Contemporary management of oropharyngeal cancer: anatomy and physiology of the oropharynx.
Duvvuri U, Myers JN
Curr Probl Surg 2009 Feb;46(2):119-84. doi: 10.1067/j.cpsurg.2008.10.003. PMID: 19111679
Carotid artery rupture.
Shumrick DA
Laryngoscope 1973 Jul;83(7):1051-61. doi: 10.1288/00005537-197307000-00006. PMID: 4581177

Prognosis

New chances and challenges for preventing HPV associated throat cancer: Otolaryngologists sense an opening for increasing vaccination rates and decreasing the incidence of HPV-associated oropharyngeal cancer.
Nelson B, Faquin W
Cancer Cytopathol 2023 Sep;131(9):540-541. doi: 10.1002/cncy.22755. PMID: 37667548
Tonsillectomy and the incidence of various types of cancer.
Holló G
Immunol Res 2021 Dec;69(6):467-470. Epub 2021 Sep 15 doi: 10.1007/s12026-021-09230-3. PMID: 34523058Free PMC Article
Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Machiels JP, René Leemans C, Golusinski W, Grau C, Licitra L, Gregoire V; EHNS Executive Board. Electronic address: [email protected]; ESMO Guidelines Committee. Electronic address: [email protected]; ESTRO Executive Board. Electronic address: [email protected]
Ann Oncol 2020 Nov;31(11):1462-1475. Epub 2020 Oct 23 doi: 10.1016/j.annonc.2020.07.011. PMID: 33239190
An unusual palatine tonsil lesion.
Fabre C, Gil H, Righini CA
Eur Ann Otorhinolaryngol Head Neck Dis 2019 Sep;136(4):331-333. Epub 2019 Jun 17 doi: 10.1016/j.anorl.2019.05.014. PMID: 31221589
Hypopharyngeal carcinoma.
Mansfield EL, Cote DN
J La State Med Soc 1995 Nov;147(11):489-92. PMID: 8522899

Clinical prediction guides

Role of chemotherapy in patients with nasopharynx carcinoma treated with radiotherapy (MAC-NPC): an updated individual patient data network meta-analysis.
Petit C, Lee A, Ma J, Lacas B, Ng WT, Chan ATC, Hong RL, Chen MY, Chen L, Li WF, Huang PY, Tan T, Ngan RKC, Zhu G, Mai HQ, Hui EP, Fountzilas G, Zhang L, Carmel A, Kwong DLW, Moon J, Bourhis J, Auperin A, Pignon JP, Blanchard P; MAC-NPC Collaborative Group
Lancet Oncol 2023 Jun;24(6):611-623. doi: 10.1016/S1470-2045(23)00163-8. PMID: 37269842
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Tonsillectomy and the incidence of various types of cancer.
Holló G
Immunol Res 2021 Dec;69(6):467-470. Epub 2021 Sep 15 doi: 10.1007/s12026-021-09230-3. PMID: 34523058Free PMC Article
Endoscopic observation of the hypopharyngeal region using a super soft hood.
Inoue T, Ishihara R, Fujii T
Dig Endosc 2021 Mar;33(3):e41-e42. Epub 2021 Jan 28 doi: 10.1111/den.13918. PMID: 33506544
Intraoperative free jejunum flap monitoring with indocyanine green near-infrared angiography.
Murono S, Ishikawa N, Ohtake H, Tsuji A, Endo K, Kondo S, Wakisaka N, Yoshizaki T
Eur Arch Otorhinolaryngol 2014 May;271(5):1335-8. Epub 2014 Feb 18 doi: 10.1007/s00405-014-2936-3. PMID: 24534897

Recent systematic reviews

Serum 25-Hydroxyvitamin D and Cancer Risk: A Systematic Review of Mendelian Randomization Studies.
Lawler T, Warren Andersen S
Nutrients 2023 Jan 13;15(2) doi: 10.3390/nu15020422. PMID: 36678292Free PMC Article
Lymphoepithelial carcinoma of larynx and hypopharynx: a systematic review and pooled analysis.
Petruzzi G, Costantino A, De Virgilio A, Zocchi J, Campo F, Mercante G, Spriano G, Pellini R
Eur Arch Otorhinolaryngol 2022 Mar;279(3):1157-1166. Epub 2021 Aug 2 doi: 10.1007/s00405-021-07011-0. PMID: 34338877
Alcohol and cancer risk: A systematic review and meta-analysis of prospective Indian studies.
Singhavi HR, Singh A, Bhattacharjee A, Talole S, Dikshit R, Chaturvedi P
Indian J Public Health 2020 Apr-Jun;64(2):186-190. doi: 10.4103/ijph.IJPH_529_19. PMID: 32584303
Revisiting the gastric pull-up for pharyngoesophageal reconstruction: A systematic review and meta-analysis of mortality and morbidity.
Butskiy O, Rahmanian R, White RA, Durham S, Anderson DW, Prisman E
J Surg Oncol 2016 Dec;114(8):907-914. Epub 2016 Oct 24 doi: 10.1002/jso.24477. PMID: 27774626
Association between helicobacter pylori infection and carcinoma of the larynx or pharynx.
Zhou J, Zhang D, Yang Y, Zhou L, Tao L
Head Neck 2016 Apr;38 Suppl 1:E2291-6. Epub 2015 Aug 28 doi: 10.1002/hed.24214. PMID: 26316145

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