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Nasopharyngeal Squamous Papilloma

MedGen UID:
236846
Concept ID:
C1336085
Neoplastic Process
Synonyms: Nasopharyngeal Papilloma; Nasopharyngeal Squamous Cell Papilloma; Nasopharynx Papilloma; Papilloma of Nasopharynx; Papilloma of the Nasopharynx; Squamous Papilloma of Nasopharynx; Squamous Papilloma of the Nasopharynx

Definition

A benign exophytic neoplasm that arises from the nasopharynx. It is characterized by the presence of a connective tissue core covered by stratified squamous epithelium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNasopharyngeal Squamous Papilloma

Professional guidelines

PubMed

Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR Jr, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Antognoni P, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz CS, Blay JY, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Castelnuovo P, Chandra RK, Chatzinakis V, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, Dallan I, Dassi CS, de Almeida J, Dei Tos AP, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Lund VJ, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Huang Z, Huang Z, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Kuo YJ, Lal D, Lamarre ED, Lan MY, Le H, Lechner M, Lee NY, Lee JK, Lee VH, Levine CG, Lin JC, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, Matnjani G, McKean EL, Meço C, Mendenhall WM, Michel L, Na'ara S, Nicolai P, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Otori N, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M Jr, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schafhausen P, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Stamm A, Stölzel K, Sumer B, Surda P, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Tsang RK, Turner JH, Turri-Zanoni M, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Wong SN, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN
Int Forum Allergy Rhinol 2024 Feb;14(2):149-608. Epub 2024 Jan 2 doi: 10.1002/alr.23262. PMID: 37658764
Kim D, Siegel J, Chouake RJ, Geliebter J, Zalvan CH
Ear Nose Throat J 2021 Aug;100(7):546-551. Epub 2019 Oct 3 doi: 10.1177/0145561319871228. PMID: 31581834
Strong MS, Vaughan CW, Cooperband SR, Healy GB, Clemente MA
Ann Otol Rhinol Laryngol 1976 Jul-Aug;85(4 Pt 1):508-16. doi: 10.1177/000348947608500412. PMID: 949157

Recent clinical studies

Etiology

Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR Jr, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Antognoni P, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz CS, Blay JY, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Castelnuovo P, Chandra RK, Chatzinakis V, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, Dallan I, Dassi CS, de Almeida J, Dei Tos AP, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Lund VJ, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Huang Z, Huang Z, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Kuo YJ, Lal D, Lamarre ED, Lan MY, Le H, Lechner M, Lee NY, Lee JK, Lee VH, Levine CG, Lin JC, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, Matnjani G, McKean EL, Meço C, Mendenhall WM, Michel L, Na'ara S, Nicolai P, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Otori N, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M Jr, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schafhausen P, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Stamm A, Stölzel K, Sumer B, Surda P, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Tsang RK, Turner JH, Turri-Zanoni M, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Wong SN, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN
Int Forum Allergy Rhinol 2024 Feb;14(2):149-608. Epub 2024 Jan 2 doi: 10.1002/alr.23262. PMID: 37658764
Pavan N, Crestani A, Abrate A, De Nunzio C, Esperto F, Giannarini G, Galfano A, Gregori A, Liguori G, Bartoletti R, Porpiglia F, Simonato A, Trombetta C, Tubaro A, Ficarra V, Novara G; Research Urology Network (RUN)
Eur Urol Focus 2020 Sep 15;6(5):1058-1069. Epub 2020 Jun 5 doi: 10.1016/j.euf.2020.05.021. PMID: 32527624Free PMC Article
Tatlı Doğan H, Kılıçarslan A, Doğan M, Süngü N, Güler Tezel G, Güler G
Pathol Res Pract 2016 Nov;212(11):1021-1026. Epub 2016 Sep 3 doi: 10.1016/j.prp.2016.08.013. PMID: 27640103
Mishra A, Sachadeva M, Jain A, Shukla NM, Pandey A
Am J Otolaryngol 2016 Jul-Aug;37(4):317-22. Epub 2016 Mar 8 doi: 10.1016/j.amjoto.2016.03.001. PMID: 27157983
Petersson F
Semin Diagn Pathol 2015 Jan;32(1):54-73. Epub 2015 Feb 25 doi: 10.1053/j.semdp.2015.02.021. PMID: 25769204

Diagnosis

Fortes HR, von Ranke FM, Escuissato DL, Araujo Neto CA, Zanetti G, Hochhegger B, Souza CA, Marchiori E
Respir Med 2017 May;126:116-121. Epub 2017 Apr 1 doi: 10.1016/j.rmed.2017.03.030. PMID: 28427542
Udager AM, McHugh JB
Surg Pathol Clin 2017 Mar;10(1):35-55. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.007. PMID: 28153135
Cosway B, Lovat P
Oral Oncol 2016 Mar;54:1-6. Epub 2016 Jan 7 doi: 10.1016/j.oraloncology.2015.12.007. PMID: 26774913
Kapadia SB, Popek EJ, Barnes L
Pathol Annu 1994;29 Pt 1:159-209. PMID: 8127623
Kassel EE, Cooper PW, Kassel RN
J Otolaryngol 1983 Feb;12(1):16-36. PMID: 6341618

Therapy

Koskinen AI, Hemminki O, Försti A, Hemminki K
BMC Cancer 2022 Mar 2;22(1):227. doi: 10.1186/s12885-022-09337-2. PMID: 35236321Free PMC Article
Kaidar-Person O, Gil Z, Billan S
Drug Resist Updat 2018 Sep;40:13-16. Epub 2018 Sep 25 doi: 10.1016/j.drup.2018.09.001. PMID: 30466712
Shin HR, Shin A, Woo H, Fox K, Walsh N, Lo YR, Wiesen E, Varghese C
Jpn J Clin Oncol 2016 Jan;46(1):13-22. Epub 2015 Nov 12 doi: 10.1093/jjco/hyv092. PMID: 26563255
Hsu HW, Wall NR, Hsueh CT, Kim S, Ferris RL, Chen CS, Mirshahidi S
Oral Oncol 2014 Jan;50(1):19-26. Epub 2013 Oct 23 doi: 10.1016/j.oraloncology.2013.10.003. PMID: 24269532
Strong MS, Vaughan CW, Cooperband SR, Healy GB, Clemente MA
Ann Otol Rhinol Laryngol 1976 Jul-Aug;85(4 Pt 1):508-16. doi: 10.1177/000348947608500412. PMID: 949157

Prognosis

Rooper LM, Agaimy A, Dickson BC, Dueber JC, Eberhart CG, Gagan J, Hartmann A, Khararjian A, London NR, MacMillan CM, Palsgrove DN, Nix JS, Sandison A, Stoehr R, Truong T, Weinreb I, Bishop JA
Am J Surg Pathol 2021 Dec 1;45(12):1682-1693. doi: 10.1097/PAS.0000000000001741. PMID: 34049316
Fortes HR, von Ranke FM, Escuissato DL, Araujo Neto CA, Zanetti G, Hochhegger B, Souza CA, Marchiori E
Respir Med 2017 May;126:116-121. Epub 2017 Apr 1 doi: 10.1016/j.rmed.2017.03.030. PMID: 28427542
Udager AM, McHugh JB
Surg Pathol Clin 2017 Mar;10(1):35-55. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.007. PMID: 28153135
Cosway B, Lovat P
Oral Oncol 2016 Mar;54:1-6. Epub 2016 Jan 7 doi: 10.1016/j.oraloncology.2015.12.007. PMID: 26774913
Kassel EE, Cooper PW, Kassel RN
J Otolaryngol 1983 Feb;12(1):16-36. PMID: 6341618

Clinical prediction guides

Koskinen AI, Hemminki O, Försti A, Hemminki K
BMC Cancer 2022 Mar 2;22(1):227. doi: 10.1186/s12885-022-09337-2. PMID: 35236321Free PMC Article
Mishra A, Sachadeva M, Jain A, Shukla NM, Pandey A
Am J Otolaryngol 2016 Jul-Aug;37(4):317-22. Epub 2016 Mar 8 doi: 10.1016/j.amjoto.2016.03.001. PMID: 27157983
Petersson F
Semin Diagn Pathol 2015 Jan;32(1):54-73. Epub 2015 Feb 25 doi: 10.1053/j.semdp.2015.02.021. PMID: 25769204
Leventhal BG, Kashima HK, Weck PW, Mounts P, Whisnant JK, Clark KL, Cohen S, Dedo HH, Donovan DJ, Fearon BW
Arch Otolaryngol Head Neck Surg 1988 Oct;114(10):1163-9. doi: 10.1001/archotol.1988.01860220097032. PMID: 3046638
Strong MS, Vaughan CW, Cooperband SR, Healy GB, Clemente MA
Ann Otol Rhinol Laryngol 1976 Jul-Aug;85(4 Pt 1):508-16. doi: 10.1177/000348947608500412. PMID: 949157

Recent systematic reviews

Pavan N, Crestani A, Abrate A, De Nunzio C, Esperto F, Giannarini G, Galfano A, Gregori A, Liguori G, Bartoletti R, Porpiglia F, Simonato A, Trombetta C, Tubaro A, Ficarra V, Novara G; Research Urology Network (RUN)
Eur Urol Focus 2020 Sep 15;6(5):1058-1069. Epub 2020 Jun 5 doi: 10.1016/j.euf.2020.05.021. PMID: 32527624Free PMC Article

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