U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Benign neoplasm of neck

MedGen UID:
195775
•Concept ID:
C0684815
•
Neoplastic Process
Synonyms: Benign Neck Neoplasm; benign neck neoplasm; Benign Neck Tumor; benign neck tumor; benign neck tumour; Benign Neoplasm of Neck; benign neoplasm of neck; Benign Neoplasm of the Neck; benign neoplasm of the neck; Benign tumor of neck; Benign Tumor of Neck; benign tumor of neck; Benign Tumor of the Neck; benign tumor of the neck; benign tumour of neck; benign tumour of the neck; neck benign neoplasm
SNOMED CT: Benign tumor of neck (92246000); Benign neoplasm of neck (92246000)
 
Monarch Initiative: MONDO:0021455

Definition

A neoplasm that arises from the neck region and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of neck

Professional guidelines

PubMed

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†.
Filetti S, Durante C, Hartl D, Leboulleux S, Locati LD, Newbold K, Papotti MG, Berruti A; ESMO Guidelines Committee. Electronic address: [email protected]
Ann Oncol 2019 Dec 1;30(12):1856-1883. doi: 10.1093/annonc/mdz400. PMID: 31549998
Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines.
Grégoire V, Ang K, Budach W, Grau C, Hamoir M, Langendijk JA, Lee A, Le QT, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Lengele B
Radiother Oncol 2014 Jan;110(1):172-81. Epub 2013 Oct 31 doi: 10.1016/j.radonc.2013.10.010. PMID: 24183870

Recent clinical studies

Etiology

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Congenital Neck Masses.
Pupić-Bakrač J, Pupić-Bakrač A, Novaković J, Skitarelić N
J Craniofac Surg 2021 Jun 1;32(4):1417-1420. doi: 10.1097/SCS.0000000000007122. PMID: 33170821
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines.
Grégoire V, Ang K, Budach W, Grau C, Hamoir M, Langendijk JA, Lee A, Le QT, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Lengele B
Radiother Oncol 2014 Jan;110(1):172-81. Epub 2013 Oct 31 doi: 10.1016/j.radonc.2013.10.010. PMID: 24183870

Diagnosis

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Congenital Neck Masses.
Pupić-Bakrač J, Pupić-Bakrač A, Novaković J, Skitarelić N
J Craniofac Surg 2021 Jun 1;32(4):1417-1420. doi: 10.1097/SCS.0000000000007122. PMID: 33170821
Vascular anomalies of the head and neck.
Alsuwailem A, Myer CM 4th, Chaudry G
Semin Pediatr Surg 2020 Oct;29(5):150968. Epub 2020 Sep 16 doi: 10.1016/j.sempedsurg.2020.150968. PMID: 33069291
Nontraumatic Head and Neck Emergencies.
Kamalian S, Avery L, Lev MH, Schaefer PW, Curtin HD, Kamalian S
Radiographics 2019 Oct;39(6):1808-1823. doi: 10.1148/rg.2019190159. PMID: 31589568
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417

Therapy

Reduced-Volume Irradiation of Uninvolved Neck in Patients With Nasopharyngeal Cancer: Updated Results From an Open-Label, Noninferiority, Multicenter, Randomized Phase III Trial.
Huang CL, Zhang N, Jiang W, Xie FY, Pei XQ, Huang SH, Wang XY, Mao YP, Li KP, Liu Q, Li JB, Liang SQ, Qin GJ, Hu WH, Zhou GQ, Ma J, Sun Y, Chen L, Tang LL
J Clin Oncol 2024 Jun 10;42(17):2021-2025. Epub 2024 Mar 20 doi: 10.1200/JCO.23.02086. PMID: 38507662
Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer.
Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
Influence of preoperative radiotherapy on head and neck free-flap reconstruction: Systematic review and meta-analysis.
Mijiti A, Kuerbantayi N, Zhang ZQ, Su MY, Zhang XH, Huojia M
Head Neck 2020 Aug;42(8):2165-2180. Epub 2020 Mar 4 doi: 10.1002/hed.26136. PMID: 32129547
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Anti-cancer effects of curcumin on head and neck cancers.
Gao W, Chan JY, Wei WI, Wong TS
Anticancer Agents Med Chem 2012 Nov;12(9):1110-6. doi: 10.2174/187152012803529736. PMID: 22583425

Prognosis

Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer.
Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
Survival outcomes after treatment of cancer of the oral cavity (1985-2015).
Zanoni DK, Montero PH, Migliacci JC, Shah JP, Wong RJ, Ganly I, Patel SG
Oral Oncol 2019 Mar;90:115-121. Epub 2019 Feb 15 doi: 10.1016/j.oraloncology.2019.02.001. PMID: 30846169Free PMC Article
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
Diffusion-Weighted Imaging in Head and Neck Cancer: Technique, Limitations, and Applications.
Connolly M, Srinivasan A
Magn Reson Imaging Clin N Am 2018 Feb;26(1):121-133. Epub 2017 Oct 14 doi: 10.1016/j.mric.2017.08.011. PMID: 29128000
Infrahyoid neck.
Sigal R
Radiol Clin North Am 1998 Sep;36(5):781-99, v. doi: 10.1016/s0033-8389(05)70064-6. PMID: 9747189

Clinical prediction guides

Advances in and applications of imaging and radiomics in head and neck cancer survivorship.
Wishart LR, Ward EC, Galloway G
Curr Opin Otolaryngol Head Neck Surg 2023 Dec 1;31(6):368-373. Epub 2023 Aug 4 doi: 10.1097/MOO.0000000000000918. PMID: 37548514
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Contemporary Management of Parapharyngeal Tumors.
Strohl MP, El-Sayed IH
Curr Oncol Rep 2019 Nov 14;21(11):103. doi: 10.1007/s11912-019-0853-8. PMID: 31728649
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Infrahyoid neck.
Sigal R
Radiol Clin North Am 1998 Sep;36(5):781-99, v. doi: 10.1016/s0033-8389(05)70064-6. PMID: 9747189

Recent systematic reviews

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Exercise and Nutrition Interventions in Patients with Head and Neck Cancer during Curative Treatment: A Systematic Review and Meta-Analysis.
Bye A, Sandmael JA, Stene GB, Thorsen L, Balstad TR, Solheim TS, Pripp AH, Oldervoll LM
Nutrients 2020 Oct 22;12(11) doi: 10.3390/nu12113233. PMID: 33105699Free PMC Article
Head and neck cancer patient-derived xenograft models - A systematic review.
Schuch LF, Silveira FM, Wagner VP, Borgato GB, Rocha GZ, Castilho RM, Vargas PA, Martins MD
Crit Rev Oncol Hematol 2020 Nov;155:103087. Epub 2020 Sep 1 doi: 10.1016/j.critrevonc.2020.103087. PMID: 32992152
Radiation-Associated Sarcoma of the Neck: Case Series and Systematic Review.
Williams L, Tmanova L, Mydlarz WK, Page B, Richmon JD, Quon H, Schmitt NC
Ann Otol Rhinol Laryngol 2018 Oct;127(10):735-740. Epub 2018 Jul 26 doi: 10.1177/0003489418789966. PMID: 30047787
Langerhans cell sarcoma of the head and neck.
Howard JE, Masterson L, Dwivedi RC, Jani P
Crit Rev Oncol Hematol 2016 Mar;99:180-8. Epub 2016 Jan 2 doi: 10.1016/j.critrevonc.2015.12.017. PMID: 26777877

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...