U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Benign neoplasm of neck

MedGen UID:
195775
•Concept ID:
C0684815
•
Neoplastic Process
Synonyms: Benign Neck Neoplasm; benign neck neoplasm; Benign Neck Tumor; benign neck tumor; benign neck tumour; Benign Neoplasm of Neck; benign neoplasm of neck; Benign Neoplasm of the Neck; benign neoplasm of the neck; Benign tumor of neck; Benign Tumor of Neck; benign tumor of neck; Benign Tumor of the Neck; benign tumor of the neck; benign tumour of neck; benign tumour of the neck; neck benign neoplasm
SNOMED CT: Benign tumor of neck (92246000); Benign neoplasm of neck (92246000)
 
Monarch Initiative: MONDO:0021455

Definition

A neoplasm that arises from the neck region and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of neck

Professional guidelines

PubMed

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Evidence-Based Clinical Practice Guidelines for Extramammary Paget Disease.
Kibbi N, Owen JL, Worley B, Wang JX, Harikumar V, Downing MB, Aasi SZ, Aung PP, Barker CA, Bolotin D, Bordeaux JS, Cartee TV, Chandra S, Cho NL, Choi JN, Chung KY, Cliby WA, Dorigo O, Eisen DB, Fujisawa Y, Golda N, Halfdanarson TR, Iavazzo C, Jiang SIB, Kanitakis J, Khan A, Kim JYS, Kuzel TM, Lawrence N, Leitao MM Jr, MacLean AB, Maher IA, Mittal BB, Nehal KS, Ozog DM, Pettaway CA, Ross JS, Rossi AM, Servaes S, Solomon MJ, Thomas VD, Tolia M, Voelzke BB, Waldman A, Wong MK, Zhou Y, Arai N, Brackett A, Ibrahim SA, Kang BY, Poon E, Alam M
JAMA Oncol 2022 Apr 1;8(4):618-628. doi: 10.1001/jamaoncol.2021.7148. PMID: 35050310
Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines.
Grégoire V, Ang K, Budach W, Grau C, Hamoir M, Langendijk JA, Lee A, Le QT, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Lengele B
Radiother Oncol 2014 Jan;110(1):172-81. Epub 2013 Oct 31 doi: 10.1016/j.radonc.2013.10.010. PMID: 24183870

Recent clinical studies

Etiology

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
Clinico-Surgical Characteristics of Head and Neck Lipomas.
Kim JS, Choi MS, Lee SJ, Park BC
Dermatol Surg 2018 Jun;44(6):893-895. doi: 10.1097/DSS.0000000000001395. PMID: 29462019
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines.
Grégoire V, Ang K, Budach W, Grau C, Hamoir M, Langendijk JA, Lee A, Le QT, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Lengele B
Radiother Oncol 2014 Jan;110(1):172-81. Epub 2013 Oct 31 doi: 10.1016/j.radonc.2013.10.010. PMID: 24183870

Diagnosis

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Congenital Neck Mass.
Sprewell AR, Holman JL, Kiell EP
Neoreviews 2021 Jun;22(6):e415-e419. doi: 10.1542/neo.22-6-e415. PMID: 34074649
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
Imaging of the perivertebral space.
Mills MK, Shah LM
Radiol Clin North Am 2015 Jan;53(1):163-80. Epub 2014 Oct 11 doi: 10.1016/j.rcl.2014.09.008. PMID: 25476179
Pediatric neck masses.
Geddes G, Butterly MM, Patel SM, Marra S
Pediatr Rev 2013 Mar;34(3):115-24; quiz 125. doi: 10.1542/pir.34-3-115. PMID: 23457198

Therapy

Reduced-Volume Irradiation of Uninvolved Neck in Patients With Nasopharyngeal Cancer: Updated Results From an Open-Label, Noninferiority, Multicenter, Randomized Phase III Trial.
Huang CL, Zhang N, Jiang W, Xie FY, Pei XQ, Huang SH, Wang XY, Mao YP, Li KP, Liu Q, Li JB, Liang SQ, Qin GJ, Hu WH, Zhou GQ, Ma J, Sun Y, Chen L, Tang LL
J Clin Oncol 2024 Jun 10;42(17):2021-2025. Epub 2024 Mar 20 doi: 10.1200/JCO.23.02086. PMID: 38507662
Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer.
Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
Point-of-Care Ultrasound in the Pediatric Emergency Department: Where We're at, Where We're Going.
Gonzalez LK, Yellin S, Arroyo AC
Adv Pediatr 2018 Aug;65(1):121-142. Epub 2018 Jun 15 doi: 10.1016/j.yapd.2018.04.001. PMID: 30053920
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Cervical teratoma.
Rundle FW
J Otolaryngol 1976 Dec;5(6):513-8. PMID: 1011335

Prognosis

Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer.
Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
Survival outcomes after treatment of cancer of the oral cavity (1985-2015).
Zanoni DK, Montero PH, Migliacci JC, Shah JP, Wong RJ, Ganly I, Patel SG
Oral Oncol 2019 Mar;90:115-121. Epub 2019 Feb 15 doi: 10.1016/j.oraloncology.2019.02.001. PMID: 30846169Free PMC Article
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
An enlarging neck mass.
Patel SA, Chambers K, Lin HW, Faquin WC, Randolph GW
JAMA Otolaryngol Head Neck Surg 2014 Feb;140(2):175-6. doi: 10.1001/jamaoto.2013.6075. PMID: 24370679
Imaging of postoperative larynx and neck.
Maroldi R
Semin Roentgenol 2000 Jan;35(1):84-100. doi: 10.1016/s0037-198x(00)80035-8. PMID: 10670056

Clinical prediction guides

Clinical prediction models for cervical lymph node metastasis of papillary thyroid carcinoma.
Luo S, Lai F, Liang R, Li B, He Y, Chen W, Zhang J, Li X, Xu T, Hou Y, Liu Y, Long J, Yang Z, Chen X
Endocrine 2024 May;84(2):646-655. Epub 2024 Jan 4 doi: 10.1007/s12020-023-03632-z. PMID: 38175390
Advances in and applications of imaging and radiomics in head and neck cancer survivorship.
Wishart LR, Ward EC, Galloway G
Curr Opin Otolaryngol Head Neck Surg 2023 Dec 1;31(6):368-373. Epub 2023 Aug 4 doi: 10.1097/MOO.0000000000000918. PMID: 37548514
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Contemporary Management of Parapharyngeal Tumors.
Strohl MP, El-Sayed IH
Curr Oncol Rep 2019 Nov 14;21(11):103. doi: 10.1007/s11912-019-0853-8. PMID: 31728649
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855

Recent systematic reviews

Treatment of Angiosarcoma of the Head and Neck: A Systematic Review.
Houpe JE, Seger EW, Neill BC, Kang BY, Hocker TLH, Alam M, Tolkachjov SN
Cutis 2023 May;111(5):247-251. doi: 10.12788/cutis.0767. PMID: 37406332
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Oral squamous cell carcinoma outcome in adolescent/young adult: Systematic review and meta-analysis.
Kaminagakura E, Tango RN, Cruz-Perez D, Bonan R, Yamamoto de Almeida L, de Almeida Lança ML, Bonan P, Martins H, Takahama A Jr, Ito FA, Coutinho-Camillo CM, Lourenço SV, Caneppele T, Sikora AG, Kowalski LP, Young S
Head Neck 2022 Feb;44(2):548-561. Epub 2021 Nov 22 doi: 10.1002/hed.26940. PMID: 34808012
Exercise and Nutrition Interventions in Patients with Head and Neck Cancer during Curative Treatment: A Systematic Review and Meta-Analysis.
Bye A, Sandmael JA, Stene GB, Thorsen L, Balstad TR, Solheim TS, Pripp AH, Oldervoll LM
Nutrients 2020 Oct 22;12(11) doi: 10.3390/nu12113233. PMID: 33105699Free PMC Article
Bilateral chylothorax following neck dissection: case report and systematic review of the literature.
Zhang H, Dziegielewski PT, Romanovsky A, Seikaly H
J Otolaryngol Head Neck Surg 2012 Aug;41(4):E26-30. PMID: 22935186

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...