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Placenta neoplasm

MedGen UID:
105551
•Concept ID:
C0524541
•
Neoplastic Process
Synonym: Neoplasm of placenta
SNOMED CT: Neoplasm of placenta (126920004)
 
Monarch Initiative: MONDO:0021218

Definition

A benign or malignant neoplasm that affects the placenta. Representative examples include hemangioma and choriocarcinoma. [from NCI]

Professional guidelines

PubMed

Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma.
Aoki S, Inoue K, Klein S, Halvorsen S, Chen J, Matsui A, Nikmaneshi MR, Kitahara S, Hato T, Chen X, Kawakubo K, Nia HT, Chen I, Schanne DH, Mamessier E, Shigeta K, Kikuchi H, Ramjiawan RR, Schmidt TC, Iwasaki M, Yau T, Hong TS, Quaas A, Plum PS, Dima S, Popescu I, Bardeesy N, Munn LL, Borad MJ, Sassi S, Jain RK, Zhu AX, Duda DG
Gut 2022 Jan;71(1):185-193. Epub 2021 Jan 11 doi: 10.1136/gutjnl-2020-322493. PMID: 33431577Free PMC Article
Diagnosis and management of gestational trophoblastic disease: 2021 update.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):86-93. doi: 10.1002/ijgo.13877. PMID: 34669197Free PMC Article
Update on the diagnosis and management of gestational trophoblastic disease.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L
Int J Gynaecol Obstet 2018 Oct;143 Suppl 2:79-85. doi: 10.1002/ijgo.12615. PMID: 30306586

Recent clinical studies

Etiology

Diagnosis and management of gestational trophoblastic disease: 2021 update.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):86-93. doi: 10.1002/ijgo.13877. PMID: 34669197Free PMC Article
Recurrent GTD and GTD coexisting with normal twin pregnancy.
Sebire NJ
Best Pract Res Clin Obstet Gynaecol 2021 Jul;74:122-130. Epub 2020 Dec 21 doi: 10.1016/j.bpobgyn.2020.12.002. PMID: 33451920
Update on the diagnosis and management of gestational trophoblastic disease.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L
Int J Gynaecol Obstet 2018 Oct;143 Suppl 2:79-85. doi: 10.1002/ijgo.12615. PMID: 30306586
The potential immune-eliciting cancer testis antigens in colorectal cancer.
Chi Soh JE, Abu N, Jamal R
Immunotherapy 2018 Sep;10(12):1093-1104. doi: 10.2217/imt-2018-0044. PMID: 30185136
Expression of Cancer-Testis Antigens in Pediatric Cancers.
Ghafouri-Fard S
Asian Pac J Cancer Prev 2015;16(13):5149-52. doi: 10.7314/apjcp.2015.16.13.5149. PMID: 26225644

Diagnosis

Diagnosis and management of gestational trophoblastic disease: 2021 update.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):86-93. doi: 10.1002/ijgo.13877. PMID: 34669197Free PMC Article
Treatment of gestational trophoblastic disease in the 2020s.
Clark JJ, Slater S, Seckl MJ
Curr Opin Obstet Gynecol 2021 Feb 1;33(1):7-12. doi: 10.1097/GCO.0000000000000674. PMID: 33337613Free PMC Article
Endometrial Stromal Neoplasm in the Placenta.
Heller D, Hatem F
Int J Gynecol Pathol 2019 Nov;38(6):e2. doi: 10.1097/PGP.0000000000000597. PMID: 31593030
Update on the diagnosis and management of gestational trophoblastic disease.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L
Int J Gynaecol Obstet 2018 Oct;143 Suppl 2:79-85. doi: 10.1002/ijgo.12615. PMID: 30306586
Clinical thermography.
Wallace JD, Cade CM
CRC Crit Rev Bioeng 1974 Feb;2(1):39-94. PMID: 4362276

Therapy

Diagnosis and management of gestational trophoblastic disease: 2021 update.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):86-93. doi: 10.1002/ijgo.13877. PMID: 34669197Free PMC Article
Treatment of gestational trophoblastic disease in the 2020s.
Clark JJ, Slater S, Seckl MJ
Curr Opin Obstet Gynecol 2021 Feb 1;33(1):7-12. doi: 10.1097/GCO.0000000000000674. PMID: 33337613Free PMC Article
The role of PIGF blockade in the treatment of colorectal cancer: overcoming the pitfalls.
Macarulla T, Montagut C, Sánchez-Martin FJ, Granja M, Verdaguer H, Sastre J, Tabernero J
Expert Opin Biol Ther 2020 Jan;20(1):15-22. Epub 2019 Oct 16 doi: 10.1080/14712598.2020.1677603. PMID: 31608707
Aflibercept.
Ciombor KK, Berlin J, Chan E
Clin Cancer Res 2013 Apr 15;19(8):1920-5. Epub 2013 Feb 26 doi: 10.1158/1078-0432.CCR-12-2911. PMID: 23444216Free PMC Article
ABCG2: structure, function and role in drug response.
Polgar O, Robey RW, Bates SE
Expert Opin Drug Metab Toxicol 2008 Jan;4(1):1-15. doi: 10.1517/17425255.4.1.1. PMID: 18370855

Prognosis

Treatment of gestational trophoblastic disease in the 2020s.
Clark JJ, Slater S, Seckl MJ
Curr Opin Obstet Gynecol 2021 Feb 1;33(1):7-12. doi: 10.1097/GCO.0000000000000674. PMID: 33337613Free PMC Article
Update on the diagnosis and management of gestational trophoblastic disease.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L
Int J Gynaecol Obstet 2018 Oct;143 Suppl 2:79-85. doi: 10.1002/ijgo.12615. PMID: 30306586
Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers.
Rousseaux S, Debernardi A, Jacquiau B, Vitte AL, Vesin A, Nagy-Mignotte H, Moro-Sibilot D, Brichon PY, Lantuejoul S, Hainaut P, Laffaire J, de Reyniès A, Beer DG, Timsit JF, Brambilla C, Brambilla E, Khochbin S
Sci Transl Med 2013 May 22;5(186):186ra66. doi: 10.1126/scitranslmed.3005723. PMID: 23698379Free PMC Article
Hormones, nevi, and melanoma: an approach to the patient.
Driscoll MS, Grant-Kels JM
J Am Acad Dermatol 2007 Dec;57(6):919-31; quiz 932-6. doi: 10.1016/j.jaad.2007.08.045. PMID: 18021848
Proliferations and tumors of intermediate trophoblast of the placental site.
Young RH, Kurman RJ, Scully RE
Semin Diagn Pathol 1988 May;5(2):223-37. PMID: 2840724

Clinical prediction guides

Diagnosis and management of gestational trophoblastic disease: 2021 update.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):86-93. doi: 10.1002/ijgo.13877. PMID: 34669197Free PMC Article
Update on the diagnosis and management of gestational trophoblastic disease.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L
Int J Gynaecol Obstet 2018 Oct;143 Suppl 2:79-85. doi: 10.1002/ijgo.12615. PMID: 30306586
Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers.
Rousseaux S, Debernardi A, Jacquiau B, Vitte AL, Vesin A, Nagy-Mignotte H, Moro-Sibilot D, Brichon PY, Lantuejoul S, Hainaut P, Laffaire J, de Reyniès A, Beer DG, Timsit JF, Brambilla C, Brambilla E, Khochbin S
Sci Transl Med 2013 May 22;5(186):186ra66. doi: 10.1126/scitranslmed.3005723. PMID: 23698379Free PMC Article
Aflibercept.
Ciombor KK, Berlin J, Chan E
Clin Cancer Res 2013 Apr 15;19(8):1920-5. Epub 2013 Feb 26 doi: 10.1158/1078-0432.CCR-12-2911. PMID: 23444216Free PMC Article
Identification and characterization of transcriptional regulatory elements of the human aromatase cytochrome P450 gene (CYP19).
Toda K, Nomoto S, Shizuta Y
J Steroid Biochem Mol Biol 1996 Jan;56(1-6 Spec No):151-9. doi: 10.1016/0960-0760(95)00232-4. PMID: 8603036

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