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Submucosal Invasion Depth

MedGen UID:
1651787
•Concept ID:
C4744479
•
Finding

Definition

A morphological finding indicating the depth of tumor invasion into the submucosal tissue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubmucosal Invasion Depth

Professional guidelines

PubMed

Treatment Decision for Locally Resected T1 Colorectal Carcinoma-Verification of the Japanese Guideline Criteria for Additional Surgery Based on Long-Term Clinical Outcomes.
Oka S, Tanaka S, Kajiwara Y, Saito S, Fukunaga Y, Takamatsu M, Kawachi H, Hotta K, Ikematsu H, Kojima M, Saito Y, Yamada M, Kanemitsu Y, Sekine S, Nagata S, Yamada K, Kobayashi N, Ishihara S, Saitoh Y, Matsuda K, Togashi K, Komori K, Ishiguro M, Kuwai T, Okuyama T, Ohuchi A, Ohnuma S, Sakamoto K, Sugai T, Katsumata K, Matsushita HO, Yamano HO, Eda H, Uraoka T, Akimoto N, Kobayashi H, Sugihara K, Ueno H
Am J Gastroenterol 2024 Oct 1;119(10):2019-2027. Epub 2024 Feb 12 doi: 10.14309/ajg.0000000000002715. PMID: 38345215Free PMC Article
Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.
Weusten BLAM, Bisschops R, Dinis-Ribeiro M, di Pietro M, Pech O, Spaander MCW, Baldaque-Silva F, Barret M, Coron E, Fernández-Esparrach G, Fitzgerald RC, Jansen M, Jovani M, Marques-de-Sa I, Rattan A, Tan WK, Verheij EPD, Zellenrath PA, Triantafyllou K, Pouw RE
Endoscopy 2023 Dec;55(12):1124-1146. Epub 2023 Oct 9 doi: 10.1055/a-2176-2440. PMID: 37813356
Risk analysis of submucosal invasive rectal carcinomas for lymph node metastasis to expand indication criteria for endoscopic resection.
Oka S, Tanaka S, Nakadoi K, Kanao H, Chayama K
Dig Endosc 2013 May;25 Suppl 2:21-5. doi: 10.1111/den.12089. PMID: 23617644

Recent clinical studies

Etiology

Treatment Decision for Locally Resected T1 Colorectal Carcinoma-Verification of the Japanese Guideline Criteria for Additional Surgery Based on Long-Term Clinical Outcomes.
Oka S, Tanaka S, Kajiwara Y, Saito S, Fukunaga Y, Takamatsu M, Kawachi H, Hotta K, Ikematsu H, Kojima M, Saito Y, Yamada M, Kanemitsu Y, Sekine S, Nagata S, Yamada K, Kobayashi N, Ishihara S, Saitoh Y, Matsuda K, Togashi K, Komori K, Ishiguro M, Kuwai T, Okuyama T, Ohuchi A, Ohnuma S, Sakamoto K, Sugai T, Katsumata K, Matsushita HO, Yamano HO, Eda H, Uraoka T, Akimoto N, Kobayashi H, Sugihara K, Ueno H
Am J Gastroenterol 2024 Oct 1;119(10):2019-2027. Epub 2024 Feb 12 doi: 10.14309/ajg.0000000000002715. PMID: 38345215Free PMC Article
Role of the artificial intelligence in the management of T1 colorectal cancer.
Ichimasa K, Kudo SE, Misawa M, Takashina Y, Yeoh KG, Miyachi H
Dig Liver Dis 2024 Jul;56(7):1144-1147. Epub 2024 Feb 3 doi: 10.1016/j.dld.2024.01.202. PMID: 38311532
Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.
Weusten BLAM, Bisschops R, Dinis-Ribeiro M, di Pietro M, Pech O, Spaander MCW, Baldaque-Silva F, Barret M, Coron E, Fernández-Esparrach G, Fitzgerald RC, Jansen M, Jovani M, Marques-de-Sa I, Rattan A, Tan WK, Verheij EPD, Zellenrath PA, Triantafyllou K, Pouw RE
Endoscopy 2023 Dec;55(12):1124-1146. Epub 2023 Oct 9 doi: 10.1055/a-2176-2440. PMID: 37813356
Nomogram as a novel predictive tool for lymph node metastasis in T1 colorectal cancer treated with endoscopic resection: a nationwide, multicenter study.
Kajiwara Y, Oka S, Tanaka S, Nakamura T, Saito S, Fukunaga Y, Takamatsu M, Kawachi H, Hotta K, Ikematsu H, Kojima M, Saito Y, Yamada M, Kanemitsu Y, Sekine S, Nagata S, Yamada K, Kobayashi N, Ishihara S, Saitoh Y, Matsuda K, Togashi K, Komori K, Ishiguro M, Kuwai T, Okuyama T, Ohuchi A, Ohnuma S, Sakamoto K, Sugai T, Katsumata K, Matsushita HO, Yamano HO, Eda H, Uraoka T, Akimoto N, Kobayashi H, Ajioka Y, Sugihara K, Ueno H
Gastrointest Endosc 2023 Jun;97(6):1119-1128.e5. Epub 2023 Jan 18 doi: 10.1016/j.gie.2023.01.022. PMID: 36669574
Practical problems of measuring depth of submucosal invasion in T1 colorectal carcinomas.
Kouyama Y, Kudo SE, Miyachi H, Ichimasa K, Hisayuki T, Oikawa H, Matsudaira S, Kimura YJ, Misawa M, Mori Y, Kodama K, Kudo T, Hayashi T, Wakamura K, Katagiri A, Hidaka E, Ishida F, Hamatani S
Int J Colorectal Dis 2016 Jan;31(1):137-46. Epub 2015 Oct 2 doi: 10.1007/s00384-015-2403-7. PMID: 26428364Free PMC Article

Diagnosis

Treatment Decision for Locally Resected T1 Colorectal Carcinoma-Verification of the Japanese Guideline Criteria for Additional Surgery Based on Long-Term Clinical Outcomes.
Oka S, Tanaka S, Kajiwara Y, Saito S, Fukunaga Y, Takamatsu M, Kawachi H, Hotta K, Ikematsu H, Kojima M, Saito Y, Yamada M, Kanemitsu Y, Sekine S, Nagata S, Yamada K, Kobayashi N, Ishihara S, Saitoh Y, Matsuda K, Togashi K, Komori K, Ishiguro M, Kuwai T, Okuyama T, Ohuchi A, Ohnuma S, Sakamoto K, Sugai T, Katsumata K, Matsushita HO, Yamano HO, Eda H, Uraoka T, Akimoto N, Kobayashi H, Sugihara K, Ueno H
Am J Gastroenterol 2024 Oct 1;119(10):2019-2027. Epub 2024 Feb 12 doi: 10.14309/ajg.0000000000002715. PMID: 38345215Free PMC Article
Role of the artificial intelligence in the management of T1 colorectal cancer.
Ichimasa K, Kudo SE, Misawa M, Takashina Y, Yeoh KG, Miyachi H
Dig Liver Dis 2024 Jul;56(7):1144-1147. Epub 2024 Feb 3 doi: 10.1016/j.dld.2024.01.202. PMID: 38311532
Precision endoscopy in colorectal polyps' characterization and planning of endoscopic therapy.
Mandarino FV, Danese S, Uraoka T, Parra-Blanco A, Maeda Y, Saito Y, Kudo SE, Bourke MJ, Iacucci M
Dig Endosc 2024 Jul;36(7):761-777. Epub 2024 Jan 22 doi: 10.1111/den.14727. PMID: 37988279
Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.
Weusten BLAM, Bisschops R, Dinis-Ribeiro M, di Pietro M, Pech O, Spaander MCW, Baldaque-Silva F, Barret M, Coron E, Fernández-Esparrach G, Fitzgerald RC, Jansen M, Jovani M, Marques-de-Sa I, Rattan A, Tan WK, Verheij EPD, Zellenrath PA, Triantafyllou K, Pouw RE
Endoscopy 2023 Dec;55(12):1124-1146. Epub 2023 Oct 9 doi: 10.1055/a-2176-2440. PMID: 37813356
Nomogram as a novel predictive tool for lymph node metastasis in T1 colorectal cancer treated with endoscopic resection: a nationwide, multicenter study.
Kajiwara Y, Oka S, Tanaka S, Nakamura T, Saito S, Fukunaga Y, Takamatsu M, Kawachi H, Hotta K, Ikematsu H, Kojima M, Saito Y, Yamada M, Kanemitsu Y, Sekine S, Nagata S, Yamada K, Kobayashi N, Ishihara S, Saitoh Y, Matsuda K, Togashi K, Komori K, Ishiguro M, Kuwai T, Okuyama T, Ohuchi A, Ohnuma S, Sakamoto K, Sugai T, Katsumata K, Matsushita HO, Yamano HO, Eda H, Uraoka T, Akimoto N, Kobayashi H, Ajioka Y, Sugihara K, Ueno H
Gastrointest Endosc 2023 Jun;97(6):1119-1128.e5. Epub 2023 Jan 18 doi: 10.1016/j.gie.2023.01.022. PMID: 36669574

Therapy

Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.
Weusten BLAM, Bisschops R, Dinis-Ribeiro M, di Pietro M, Pech O, Spaander MCW, Baldaque-Silva F, Barret M, Coron E, Fernández-Esparrach G, Fitzgerald RC, Jansen M, Jovani M, Marques-de-Sa I, Rattan A, Tan WK, Verheij EPD, Zellenrath PA, Triantafyllou K, Pouw RE
Endoscopy 2023 Dec;55(12):1124-1146. Epub 2023 Oct 9 doi: 10.1055/a-2176-2440. PMID: 37813356
Short-term safety of adjuvant chemoradiotherapy after local resection for patients with high-risk submucosal invasive rectal cancer: a single-arm, multicenter phase II trial.
Noguchi M, Shitara K, Kawazoe A, Yamamoto D, Takii Y, Saito Y, Sato T, Horimatsu T, Ishikawa H, Ito Y, Ito M, Ikematsu H
Jpn J Clin Oncol 2021 Apr 30;51(5):707-712. doi: 10.1093/jjco/hyaa260. PMID: 33558891Free PMC Article
Prevalence and risk factors for lymph node metastasis after noncurative endoscopic resection for early gastric cancer: a systematic review and meta-analysis.
Hatta W, Gotoda T, Kanno T, Yuan Y, Koike T, Moayyedi P, Masamune A
J Gastroenterol 2020 Aug;55(8):742-753. Epub 2020 Apr 10 doi: 10.1007/s00535-020-01685-9. PMID: 32277297

Prognosis

Precision endoscopy in colorectal polyps' characterization and planning of endoscopic therapy.
Mandarino FV, Danese S, Uraoka T, Parra-Blanco A, Maeda Y, Saito Y, Kudo SE, Bourke MJ, Iacucci M
Dig Endosc 2024 Jul;36(7):761-777. Epub 2024 Jan 22 doi: 10.1111/den.14727. PMID: 37988279
Invasion depth estimation of carcinoma cells using adaptive stain normalization to improve epidermis segmentation accuracy.
Hoque MZ, Keskinarkaus A, Nyberg P, Xu H, Seppänen T
Comput Med Imaging Graph 2023 Sep;108:102276. Epub 2023 Jul 31 doi: 10.1016/j.compmedimag.2023.102276. PMID: 37611486
Nomogram as a novel predictive tool for lymph node metastasis in T1 colorectal cancer treated with endoscopic resection: a nationwide, multicenter study.
Kajiwara Y, Oka S, Tanaka S, Nakamura T, Saito S, Fukunaga Y, Takamatsu M, Kawachi H, Hotta K, Ikematsu H, Kojima M, Saito Y, Yamada M, Kanemitsu Y, Sekine S, Nagata S, Yamada K, Kobayashi N, Ishihara S, Saitoh Y, Matsuda K, Togashi K, Komori K, Ishiguro M, Kuwai T, Okuyama T, Ohuchi A, Ohnuma S, Sakamoto K, Sugai T, Katsumata K, Matsushita HO, Yamano HO, Eda H, Uraoka T, Akimoto N, Kobayashi H, Ajioka Y, Sugihara K, Ueno H
Gastrointest Endosc 2023 Jun;97(6):1119-1128.e5. Epub 2023 Jan 18 doi: 10.1016/j.gie.2023.01.022. PMID: 36669574
Role of barium enema examination for the diagnosis of submucosal invasion depth in T1 colorectal cancers.
Kawasaki K, Torisu T, Nagahata T, Esaki M, Kurahara K, Eizuka M, Tanaka Y, Fujiwara M, Kawatoko S, Oshiro Y, Yamada S, Ikegami K, Fujioka S, Fuyuno Y, Matsuno Y, Umeno J, Moriyama T, Kitazono T, Sugai T, Matsumoto T
Cancer Imaging 2021 Dec 7;21(1):66. doi: 10.1186/s40644-021-00437-z. PMID: 34876222Free PMC Article
Risk analysis of submucosal invasive rectal carcinomas for lymph node metastasis to expand indication criteria for endoscopic resection.
Oka S, Tanaka S, Nakadoi K, Kanao H, Chayama K
Dig Endosc 2013 May;25 Suppl 2:21-5. doi: 10.1111/den.12089. PMID: 23617644

Clinical prediction guides

Precision endoscopy in colorectal polyps' characterization and planning of endoscopic therapy.
Mandarino FV, Danese S, Uraoka T, Parra-Blanco A, Maeda Y, Saito Y, Kudo SE, Bourke MJ, Iacucci M
Dig Endosc 2024 Jul;36(7):761-777. Epub 2024 Jan 22 doi: 10.1111/den.14727. PMID: 37988279
Invasion depth estimation of carcinoma cells using adaptive stain normalization to improve epidermis segmentation accuracy.
Hoque MZ, Keskinarkaus A, Nyberg P, Xu H, Seppänen T
Comput Med Imaging Graph 2023 Sep;108:102276. Epub 2023 Jul 31 doi: 10.1016/j.compmedimag.2023.102276. PMID: 37611486
Nomogram as a novel predictive tool for lymph node metastasis in T1 colorectal cancer treated with endoscopic resection: a nationwide, multicenter study.
Kajiwara Y, Oka S, Tanaka S, Nakamura T, Saito S, Fukunaga Y, Takamatsu M, Kawachi H, Hotta K, Ikematsu H, Kojima M, Saito Y, Yamada M, Kanemitsu Y, Sekine S, Nagata S, Yamada K, Kobayashi N, Ishihara S, Saitoh Y, Matsuda K, Togashi K, Komori K, Ishiguro M, Kuwai T, Okuyama T, Ohuchi A, Ohnuma S, Sakamoto K, Sugai T, Katsumata K, Matsushita HO, Yamano HO, Eda H, Uraoka T, Akimoto N, Kobayashi H, Ajioka Y, Sugihara K, Ueno H
Gastrointest Endosc 2023 Jun;97(6):1119-1128.e5. Epub 2023 Jan 18 doi: 10.1016/j.gie.2023.01.022. PMID: 36669574
Role of barium enema examination for the diagnosis of submucosal invasion depth in T1 colorectal cancers.
Kawasaki K, Torisu T, Nagahata T, Esaki M, Kurahara K, Eizuka M, Tanaka Y, Fujiwara M, Kawatoko S, Oshiro Y, Yamada S, Ikegami K, Fujioka S, Fuyuno Y, Matsuno Y, Umeno J, Moriyama T, Kitazono T, Sugai T, Matsumoto T
Cancer Imaging 2021 Dec 7;21(1):66. doi: 10.1186/s40644-021-00437-z. PMID: 34876222Free PMC Article
Do pathologists agree with each other on the histological assessment of pT1b oesophageal adenocarcinoma?
Gotink AW, Ten Kate FJ, Doukas M, Wijnhoven BP, Bruno MJ, Looijenga LH, Koch AD, Biermann K
United European Gastroenterol J 2019 Mar;7(2):261-269. Epub 2018 Dec 6 doi: 10.1177/2050640618817693. PMID: 31080611Free PMC Article

Recent systematic reviews

Prevalence and risk factors for lymph node metastasis after noncurative endoscopic resection for early gastric cancer: a systematic review and meta-analysis.
Hatta W, Gotoda T, Kanno T, Yuan Y, Koike T, Moayyedi P, Masamune A
J Gastroenterol 2020 Aug;55(8):742-753. Epub 2020 Apr 10 doi: 10.1007/s00535-020-01685-9. PMID: 32277297

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