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Pancreatobiliary Carcinoma

MedGen UID:
1715998
•Concept ID:
C5237970
•
Neoplastic Process
Synonyms: Pancreaticobiliary Cancer; Pancreaticobiliary Carcinoma; Pancreatobiliary Cancer

Definition

A carcinoma that arises from the pancreas, bile ducts, gallbladder, or ampulla of Vater. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPancreatobiliary Carcinoma

Professional guidelines

PubMed

REDISCOVER International Guidelines on the Perioperative Care of Surgical Patients With Borderline-resectable and Locally Advanced Pancreatic Cancer.
Boggi U, Kauffmann E, Napoli N, Barreto SG, Besselink MG, Fusai GK, Hackert T, Abu Hilal M, Marchegiani G, Salvia R, Shrikhande SV, Truty M, Werner J, Wolfgang CL, Bannone E, Capretti G, Cattelani A, Coppola A, Cucchetti A, De Sio D, Di Dato A, Di Meo G, Fiorillo C, Gianfaldoni C, Ginesini M, Hidalgo Salinas C, Lai Q, Miccoli M, Montorsi R, Pagnanelli M, Poli A, Ricci C, Sucameli F, Tamburrino D, Viti V, Addeo PF, Alfieri S, Bachellier P, Baiocchi GL, Balzano G, Barbarello L, Brolese A, Busquets J, Butturini G, Caniglia F, Caputo D, Casadei R, Chunhua X, Colangelo E, Coratti A, Costa F, Crafa F, Dalla Valle R, De Carlis L, de Wilde RF, Del Chiaro M, Di Benedetto F, Di Sebastiano P, Dokmak S, Hogg M, Egorov VI, Ercolani G, Ettorre GM, Falconi M, Ferrari G, Ferrero A, Filauro M, Giardino A, Grazi GL, Gruttadauria S, Izbicki JR, Jovine E, Katz M, Keck T, Khatkov I, Kiguchi G, Kooby D, Lang H, Lombardo C, Malleo G, Massani M, Mazzaferro V, Memeo R, Miao Y, Mishima K, Molino C, Nagakawa Y, Nakamura M, Nardo B, Panaro F, Pasquali C, Perrone V, Rangelova E, Liu R, Romagnoli R, Romito R, Rosso E, Schulick R, Siriwardena A, Spampinato MG, Strobel O, Testini M, Troisi RI, Uzunoglo FG, Valente R, Veneroni L, Zerbi A, Vicente E, Vistoli F, Vivarelli M, Wakabayashi G, Zanus G, Zureikat A, Zyromski NJ, Coppola R, D'Andrea V, Davide J, Dervenis C, Frigerio I, Konlon KC, Michelassi F, Montorsi M, Nealon W, Portolani N, Sousa Silva D, Bozzi G, Ferrari V, Trivella MG, Cameron J, Clavien PA, Asbun HJ; REDISCOVER Multidisciplinary Advisory Board
Ann Surg 2024 Jul 1;280(1):56-65. Epub 2024 Feb 26 doi: 10.1097/SLA.0000000000006248. PMID: 38407228Free PMC Article
Merits and boundaries of the BCLC staging and treatment algorithm: Learning from the past to improve the future with a novel proposal.
Trevisani F, Vitale A, Kudo M, Kulik L, Park JW, Pinato DJ, Cillo U
J Hepatol 2024 Apr;80(4):661-669. Epub 2024 Jan 22 doi: 10.1016/j.jhep.2024.01.010. PMID: 38266658
Transarterial chemoembolization for hepatocellular carcinoma: 2023 Expert consensus-based practical recommendations of the Korean Liver Cancer Association.
Cho Y, Choi JW, Kwon H, Kim KY, Lee BC, Chu HH, Lee DH, Lee HA, Kim GM, Oh JS, Hyun D, Lee IJ, Rhim H; Research Committee of the Korean Liver Cancer Association
Clin Mol Hepatol 2023 Jul;29(3):521-541. Epub 2023 Jul 1 doi: 10.3350/cmh.2023.0202. PMID: 37482892Free PMC Article

Recent clinical studies

Etiology

SPARC expression in desmoplastic and non desmoplastic pancreatic carcinoma and cholangiocarcinoma.
Khetan K, Baloda V, Sahoo RK, Vishnubhathla S, Yadav R, Saraya A, Sharma A, Gupta SD, Das P
Pathol Res Pract 2019 Dec;215(12):152685. Epub 2019 Oct 21 doi: 10.1016/j.prp.2019.152685. PMID: 31727501
Dysplasia in Gallbladder: What Should We Do?
Rais R, González I, Chatterjee D
J Gastrointest Surg 2019 Apr;23(4):686-689. Epub 2018 Sep 13 doi: 10.1007/s11605-018-3955-y. PMID: 30215198
Strategies for improving diagnostic accuracy of biliary strictures.
Salomao M, Gonda TA, Margolskee E, Eguia V, Remotti H, Poneros JM, Sethi A, Saqi A
Cancer Cytopathol 2015 Apr;123(4):244-52. Epub 2015 Jan 6 doi: 10.1002/cncy.21509. PMID: 25564796
Differential features of pancreatobiliary- and intestinal-type ampullary carcinomas at MR imaging.
Chung YE, Kim MJ, Park MS, Choi JY, Kim H, Kim SK, Lee M, Kim HJ, Choi JS, Song SY, Kim KW
Radiology 2010 Nov;257(2):384-93. Epub 2010 Sep 9 doi: 10.1148/radiol.10100200. PMID: 20829529
Diagnosis of portal venous invasion by pancreatobiliary carcinoma: value of endoscopic ultrasonography.
Sugiyama M, Hagi H, Atomi Y, Saito M
Abdom Imaging 1997 Jul-Aug;22(4):434-8. doi: 10.1007/s002619900227. PMID: 9157867

Diagnosis

Dysplasia in Gallbladder: What Should We Do?
Rais R, González I, Chatterjee D
J Gastrointest Surg 2019 Apr;23(4):686-689. Epub 2018 Sep 13 doi: 10.1007/s11605-018-3955-y. PMID: 30215198
Strategies for improving diagnostic accuracy of biliary strictures.
Salomao M, Gonda TA, Margolskee E, Eguia V, Remotti H, Poneros JM, Sethi A, Saqi A
Cancer Cytopathol 2015 Apr;123(4):244-52. Epub 2015 Jan 6 doi: 10.1002/cncy.21509. PMID: 25564796
FISHing for pancreatobiliary tract malignancy in endoscopic brushings enhances the sensitivity of routine cytology.
Barr Fritcher EG, Kipp BR, Halling KC, Clayton AC
Cytopathology 2014 Oct;25(5):288-301. Epub 2014 Jul 30 doi: 10.1111/cyt.12170. PMID: 25073411
Clinical significance of MUC1, MUC2 and CK17 expression patterns for diagnosis of pancreatobiliary arcinoma.
Yang HS, Tamayo R, Almonte M, Horten B, DaSilva M, Gangi M, Vazquez E, Joseph D, Okamoto P, Scholl T
Biotech Histochem 2012 Feb;87(2):126-32. Epub 2011 Mar 28 doi: 10.3109/10520295.2011.570276. PMID: 21438791
Diagnosis of portal venous invasion by pancreatobiliary carcinoma: value of endoscopic ultrasonography.
Sugiyama M, Hagi H, Atomi Y, Saito M
Abdom Imaging 1997 Jul-Aug;22(4):434-8. doi: 10.1007/s002619900227. PMID: 9157867

Therapy

Extrapancreatic neural plexus invasion by carcinomas of the pancreatic head region: evaluation using thin-section helical CT.
Tian H, Mori H, Matsumoto S, Yamada Y, Kiyosue H, Ohta M, Kitano S
Radiat Med 2007 May;25(4):141-7. Epub 2007 May 28 doi: 10.1007/s11604-006-0115-1. PMID: 17514364
Intraportal endovascular ultrasonography in the diagnosis of portal vein invasion by pancreatobiliary carcinoma.
Kaneko T, Nakao A, Inoue S, Harada A, Nonami T, Itoh S, Endo T, Takagi H
Ann Surg 1995 Dec;222(6):711-8. doi: 10.1097/00000658-199512000-00004. PMID: 8526577Free PMC Article

Prognosis

SPARC expression in desmoplastic and non desmoplastic pancreatic carcinoma and cholangiocarcinoma.
Khetan K, Baloda V, Sahoo RK, Vishnubhathla S, Yadav R, Saraya A, Sharma A, Gupta SD, Das P
Pathol Res Pract 2019 Dec;215(12):152685. Epub 2019 Oct 21 doi: 10.1016/j.prp.2019.152685. PMID: 31727501
Dysplasia in Gallbladder: What Should We Do?
Rais R, González I, Chatterjee D
J Gastrointest Surg 2019 Apr;23(4):686-689. Epub 2018 Sep 13 doi: 10.1007/s11605-018-3955-y. PMID: 30215198
Pathologic Subtypes of Ampullary Adenocarcinoma: Value of Ampullary MDCT for Noninvasive Preoperative Differentiation.
Ivanovic AM, Alessandrino F, Maksimovic R, Micev M, Ostojic S, Gore RM, Mortele KJ
AJR Am J Roentgenol 2017 Mar;208(3):W71-W78. Epub 2017 Jan 17 doi: 10.2214/AJR.16.16723. PMID: 28095024
Strategies for improving diagnostic accuracy of biliary strictures.
Salomao M, Gonda TA, Margolskee E, Eguia V, Remotti H, Poneros JM, Sethi A, Saqi A
Cancer Cytopathol 2015 Apr;123(4):244-52. Epub 2015 Jan 6 doi: 10.1002/cncy.21509. PMID: 25564796
Differential features of pancreatobiliary- and intestinal-type ampullary carcinomas at MR imaging.
Chung YE, Kim MJ, Park MS, Choi JY, Kim H, Kim SK, Lee M, Kim HJ, Choi JS, Song SY, Kim KW
Radiology 2010 Nov;257(2):384-93. Epub 2010 Sep 9 doi: 10.1148/radiol.10100200. PMID: 20829529

Clinical prediction guides

Clinicopathological Characteristics of Ovarian Metastasis from Colorectal and Pancreatobiliary Carcinomas Mimicking Primary Ovarian Mucinous Tumor.
Park CK, Kim HS
Anticancer Res 2018 Sep;38(9):5465-5473. doi: 10.21873/anticanres.12879. PMID: 30194204
Pathologic Subtypes of Ampullary Adenocarcinoma: Value of Ampullary MDCT for Noninvasive Preoperative Differentiation.
Ivanovic AM, Alessandrino F, Maksimovic R, Micev M, Ostojic S, Gore RM, Mortele KJ
AJR Am J Roentgenol 2017 Mar;208(3):W71-W78. Epub 2017 Jan 17 doi: 10.2214/AJR.16.16723. PMID: 28095024
Contrast-enhanced harmonic endoscopic ultrasonography for assessment of lymph node metastases in pancreatobiliary carcinoma.
Miyata T, Kitano M, Omoto S, Kadosaka K, Kamata K, Imai H, Sakamoto H, Nisida N, Harwani Y, Murakami T, Takeyama Y, Chiba Y, Kudo M
World J Gastroenterol 2016 Mar 28;22(12):3381-91. doi: 10.3748/wjg.v22.i12.3381. PMID: 27022220Free PMC Article
Strategies for improving diagnostic accuracy of biliary strictures.
Salomao M, Gonda TA, Margolskee E, Eguia V, Remotti H, Poneros JM, Sethi A, Saqi A
Cancer Cytopathol 2015 Apr;123(4):244-52. Epub 2015 Jan 6 doi: 10.1002/cncy.21509. PMID: 25564796
Intraportal endovascular ultrasonography in the diagnosis of portal vein invasion by pancreatobiliary carcinoma.
Kaneko T, Nakao A, Inoue S, Harada A, Nonami T, Itoh S, Endo T, Takagi H
Ann Surg 1995 Dec;222(6):711-8. doi: 10.1097/00000658-199512000-00004. PMID: 8526577Free PMC Article

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