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Refractory Ovarian Serous Adenocarcinoma

MedGen UID:
1729725
Concept ID:
C5418953
Neoplastic Process

Definition

Ovarian serous adenocarcinoma that is resistant to treatment. [from NCI]

Professional guidelines

PubMed

Li Y, Yang Y, Shang YM, Zheng H
Indian J Cancer 2014 Mar;51 Suppl 3:e92-4. doi: 10.4103/0019-509X.154079. PMID: 25818742
Srisuttayasathien M, Khemapech N
Asian Pac J Cancer Prev 2013;14(12):7669-74. doi: 10.7314/apjcp.2013.14.12.7669. PMID: 24460351
Meyer T, Nelstrop AE, Mahmoudi M, Rustin GJ
Ann Oncol 2001 Dec;12(12):1705-9. doi: 10.1023/a:1013558501425. PMID: 11843248

Recent clinical studies

Etiology

Montemorano L, Shultz ZB, Farooque A, Hyun M, Chappell RJ, Hartenbach EM, Lang JD
Gynecol Oncol 2024 Jul;186:26-34. Epub 2024 Mar 30 doi: 10.1016/j.ygyno.2024.03.023. PMID: 38555766Free PMC Article
Lee JM, Nair J, Zimmer A, Lipkowitz S, Annunziata CM, Merino MJ, Swisher EM, Harrell MI, Trepel JB, Lee MJ, Bagheri MH, Botesteanu DA, Steinberg SM, Minasian L, Ekwede I, Kohn EC
Lancet Oncol 2018 Feb;19(2):207-215. Epub 2018 Jan 18 doi: 10.1016/S1470-2045(18)30009-3. PMID: 29361470Free PMC Article
Patch AM, Christie EL, Etemadmoghadam D, Garsed DW, George J, Fereday S, Nones K, Cowin P, Alsop K, Bailey PJ, Kassahn KS, Newell F, Quinn MC, Kazakoff S, Quek K, Wilhelm-Benartzi C, Curry E, Leong HS; Australian Ovarian Cancer Study Group, Hamilton A, Mileshkin L, Au-Yeung G, Kennedy C, Hung J, Chiew YE, Harnett P, Friedlander M, Quinn M, Pyman J, Cordner S, O'Brien P, Leditschke J, Young G, Strachan K, Waring P, Azar W, Mitchell C, Traficante N, Hendley J, Thorne H, Shackleton M, Miller DK, Arnau GM, Tothill RW, Holloway TP, Semple T, Harliwong I, Nourse C, Nourbakhsh E, Manning S, Idrisoglu S, Bruxner TJ, Christ AN, Poudel B, Holmes O, Anderson M, Leonard C, Lonie A, Hall N, Wood S, Taylor DF, Xu Q, Fink JL, Waddell N, Drapkin R, Stronach E, Gabra H, Brown R, Jewell A, Nagaraj SH, Markham E, Wilson PJ, Ellul J, McNally O, Doyle MA, Vedururu R, Stewart C, Lengyel E, Pearson JV, Waddell N, deFazio A, Grimmond SM, Bowtell DD
Nature 2015 May 28;521(7553):489-94. doi: 10.1038/nature14410. PMID: 26017449
Chumworathayi B
Asian Pac J Cancer Prev 2013;14(3):1661-4. doi: 10.7314/apjcp.2013.14.3.1661. PMID: 23679252
Manetta A, Boyle J, Berman ML, DiSaia PJ, Lentz S, Liao SY, Mutch D, Slater L
Cancer 1994 Jan 1;73(1):196-9. doi: 10.1002/1097-0142(19940101)73:1<196::aid-cncr2820730134>3.0.co;2-f. PMID: 8275425

Diagnosis

Sun Y, Patterson-Fortin J, Han S, Li Z, Nowicka Z, Hirohashi Y, Kilgas S, Yi JK, Spektor A, Fendler W, Konstantinopoulos PA, Chowdhury D
Nat Commun 2024 Aug 6;15(1):6676. doi: 10.1038/s41467-024-50999-2. PMID: 39107288Free PMC Article
Montemorano L, Shultz ZB, Farooque A, Hyun M, Chappell RJ, Hartenbach EM, Lang JD
Gynecol Oncol 2024 Jul;186:26-34. Epub 2024 Mar 30 doi: 10.1016/j.ygyno.2024.03.023. PMID: 38555766Free PMC Article
Chowdhury S, Kennedy JJ, Ivey RG, Murillo OD, Hosseini N, Song X, Petralia F, Calinawan A, Savage SR, Berry AB, Reva B, Ozbek U, Krek A, Ma W, da Veiga Leprevost F, Ji J, Yoo S, Lin C, Voytovich UJ, Huang Y, Lee SH, Bergan L, Lorentzen TD, Mesri M, Rodriguez H, Hoofnagle AN, Herbert ZT, Nesvizhskii AI, Zhang B, Whiteaker JR, Fenyo D, McKerrow W, Wang J, Schürer SC, Stathias V, Chen XS, Barcellos-Hoff MH, Starr TK, Winterhoff BJ, Nelson AC, Mok SC, Kaufmann SH, Drescher C, Cieslik M, Wang P, Birrer MJ, Paulovich AG
Cell 2023 Aug 3;186(16):3476-3498.e35. doi: 10.1016/j.cell.2023.07.004. PMID: 37541199Free PMC Article
Huang D, Chowdhury S, Wang H, Savage SR, Ivey RG, Kennedy JJ, Whiteaker JR, Lin C, Hou X, Oberg AL, Larson MC, Eskandari N, Delisi DA, Gentile S, Huntoon CJ, Voytovich UJ, Shire ZJ, Yu Q, Gygi SP, Hoofnagle AN, Herbert ZT, Lorentzen TD, Calinawan A, Karnitz LM, Weroha SJ, Kaufmann SH, Zhang B, Wang P, Birrer MJ, Paulovich AG
Cell Rep Med 2021 Dec 21;2(12):100471. doi: 10.1016/j.xcrm.2021.100471. PMID: 35028612Free PMC Article
Patch AM, Christie EL, Etemadmoghadam D, Garsed DW, George J, Fereday S, Nones K, Cowin P, Alsop K, Bailey PJ, Kassahn KS, Newell F, Quinn MC, Kazakoff S, Quek K, Wilhelm-Benartzi C, Curry E, Leong HS; Australian Ovarian Cancer Study Group, Hamilton A, Mileshkin L, Au-Yeung G, Kennedy C, Hung J, Chiew YE, Harnett P, Friedlander M, Quinn M, Pyman J, Cordner S, O'Brien P, Leditschke J, Young G, Strachan K, Waring P, Azar W, Mitchell C, Traficante N, Hendley J, Thorne H, Shackleton M, Miller DK, Arnau GM, Tothill RW, Holloway TP, Semple T, Harliwong I, Nourse C, Nourbakhsh E, Manning S, Idrisoglu S, Bruxner TJ, Christ AN, Poudel B, Holmes O, Anderson M, Leonard C, Lonie A, Hall N, Wood S, Taylor DF, Xu Q, Fink JL, Waddell N, Drapkin R, Stronach E, Gabra H, Brown R, Jewell A, Nagaraj SH, Markham E, Wilson PJ, Ellul J, McNally O, Doyle MA, Vedururu R, Stewart C, Lengyel E, Pearson JV, Waddell N, deFazio A, Grimmond SM, Bowtell DD
Nature 2015 May 28;521(7553):489-94. doi: 10.1038/nature14410. PMID: 26017449

Therapy

Emmanuelli A, Salvagno C, Hwang SM, Awasthi D, Sandoval TA, Chae CS, Cheong JG, Tan C, Iwawaki T, Cubillos-Ruiz JR
Oncoimmunology 2024;13(1):2411070. Epub 2024 Oct 2 doi: 10.1080/2162402X.2024.2411070. PMID: 39364290Free PMC Article
Sun Y, Patterson-Fortin J, Han S, Li Z, Nowicka Z, Hirohashi Y, Kilgas S, Yi JK, Spektor A, Fendler W, Konstantinopoulos PA, Chowdhury D
Nat Commun 2024 Aug 6;15(1):6676. doi: 10.1038/s41467-024-50999-2. PMID: 39107288Free PMC Article
Huang D, Chowdhury S, Wang H, Savage SR, Ivey RG, Kennedy JJ, Whiteaker JR, Lin C, Hou X, Oberg AL, Larson MC, Eskandari N, Delisi DA, Gentile S, Huntoon CJ, Voytovich UJ, Shire ZJ, Yu Q, Gygi SP, Hoofnagle AN, Herbert ZT, Lorentzen TD, Calinawan A, Karnitz LM, Weroha SJ, Kaufmann SH, Zhang B, Wang P, Birrer MJ, Paulovich AG
Cell Rep Med 2021 Dec 21;2(12):100471. doi: 10.1016/j.xcrm.2021.100471. PMID: 35028612Free PMC Article
Chumworathayi B
Asian Pac J Cancer Prev 2013;14(3):1661-4. doi: 10.7314/apjcp.2013.14.3.1661. PMID: 23679252
Fujiwara K, Suzuki S, Yoden E, Ishikawa H, Imajo Y, Kohno I
Int J Gynecol Cancer 2002 May-Jun;12(3):250-6. doi: 10.1046/j.1525-1438.2002.01096.x. PMID: 12060445

Prognosis

Chowdhury S, Kennedy JJ, Ivey RG, Murillo OD, Hosseini N, Song X, Petralia F, Calinawan A, Savage SR, Berry AB, Reva B, Ozbek U, Krek A, Ma W, da Veiga Leprevost F, Ji J, Yoo S, Lin C, Voytovich UJ, Huang Y, Lee SH, Bergan L, Lorentzen TD, Mesri M, Rodriguez H, Hoofnagle AN, Herbert ZT, Nesvizhskii AI, Zhang B, Whiteaker JR, Fenyo D, McKerrow W, Wang J, Schürer SC, Stathias V, Chen XS, Barcellos-Hoff MH, Starr TK, Winterhoff BJ, Nelson AC, Mok SC, Kaufmann SH, Drescher C, Cieslik M, Wang P, Birrer MJ, Paulovich AG
Cell 2023 Aug 3;186(16):3476-3498.e35. doi: 10.1016/j.cell.2023.07.004. PMID: 37541199Free PMC Article
Hillemeyer L, Espinoza-Sanchez NA, Greve B, Hassan N, Chelariu-Raicu A, Kiesel L, Götte M
Int J Mol Sci 2022 May 21;23(10) doi: 10.3390/ijms23105793. PMID: 35628603Free PMC Article
Lin DI, Killian JK, Venstrom JM, Ramkissoon SH, Ross JS, Elvin JA
Mod Pathol 2021 May;34(5):983-993. Epub 2020 Oct 19 doi: 10.1038/s41379-020-00699-1. PMID: 33077920
Chumworathayi B
Asian Pac J Cancer Prev 2013;14(3):1661-4. doi: 10.7314/apjcp.2013.14.3.1661. PMID: 23679252
Manetta A, Boyle J, Berman ML, DiSaia PJ, Lentz S, Liao SY, Mutch D, Slater L
Cancer 1994 Jan 1;73(1):196-9. doi: 10.1002/1097-0142(19940101)73:1<196::aid-cncr2820730134>3.0.co;2-f. PMID: 8275425

Clinical prediction guides

Montemorano L, Shultz ZB, Farooque A, Hyun M, Chappell RJ, Hartenbach EM, Lang JD
Gynecol Oncol 2024 Jul;186:26-34. Epub 2024 Mar 30 doi: 10.1016/j.ygyno.2024.03.023. PMID: 38555766Free PMC Article
Scalise CB, Kincaid K, Thigpen H, Moore J, Dover B, Norian L, Meza-Perez S, Randall T, Birrer M, Odunsi K, Arend RC
Gynecol Oncol 2024 Jun;185:83-94. Epub 2024 Feb 20 doi: 10.1016/j.ygyno.2024.02.008. PMID: 38377762
Chowdhury S, Kennedy JJ, Ivey RG, Murillo OD, Hosseini N, Song X, Petralia F, Calinawan A, Savage SR, Berry AB, Reva B, Ozbek U, Krek A, Ma W, da Veiga Leprevost F, Ji J, Yoo S, Lin C, Voytovich UJ, Huang Y, Lee SH, Bergan L, Lorentzen TD, Mesri M, Rodriguez H, Hoofnagle AN, Herbert ZT, Nesvizhskii AI, Zhang B, Whiteaker JR, Fenyo D, McKerrow W, Wang J, Schürer SC, Stathias V, Chen XS, Barcellos-Hoff MH, Starr TK, Winterhoff BJ, Nelson AC, Mok SC, Kaufmann SH, Drescher C, Cieslik M, Wang P, Birrer MJ, Paulovich AG
Cell 2023 Aug 3;186(16):3476-3498.e35. doi: 10.1016/j.cell.2023.07.004. PMID: 37541199Free PMC Article
Hillemeyer L, Espinoza-Sanchez NA, Greve B, Hassan N, Chelariu-Raicu A, Kiesel L, Götte M
Int J Mol Sci 2022 May 21;23(10) doi: 10.3390/ijms23105793. PMID: 35628603Free PMC Article
Patch AM, Christie EL, Etemadmoghadam D, Garsed DW, George J, Fereday S, Nones K, Cowin P, Alsop K, Bailey PJ, Kassahn KS, Newell F, Quinn MC, Kazakoff S, Quek K, Wilhelm-Benartzi C, Curry E, Leong HS; Australian Ovarian Cancer Study Group, Hamilton A, Mileshkin L, Au-Yeung G, Kennedy C, Hung J, Chiew YE, Harnett P, Friedlander M, Quinn M, Pyman J, Cordner S, O'Brien P, Leditschke J, Young G, Strachan K, Waring P, Azar W, Mitchell C, Traficante N, Hendley J, Thorne H, Shackleton M, Miller DK, Arnau GM, Tothill RW, Holloway TP, Semple T, Harliwong I, Nourse C, Nourbakhsh E, Manning S, Idrisoglu S, Bruxner TJ, Christ AN, Poudel B, Holmes O, Anderson M, Leonard C, Lonie A, Hall N, Wood S, Taylor DF, Xu Q, Fink JL, Waddell N, Drapkin R, Stronach E, Gabra H, Brown R, Jewell A, Nagaraj SH, Markham E, Wilson PJ, Ellul J, McNally O, Doyle MA, Vedururu R, Stewart C, Lengyel E, Pearson JV, Waddell N, deFazio A, Grimmond SM, Bowtell DD
Nature 2015 May 28;521(7553):489-94. doi: 10.1038/nature14410. PMID: 26017449

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