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Oral Cavity Adenoma

MedGen UID:: 233793
•Concept ID:: C1335116
•: Neoplastic Process

Synonyms:

Adenoma of Mouth; Adenoma of Oral Cavity; Adenoma of the Mouth; Adenoma of the Oral Cavity; Mouth Adenoma

Definition

A monomorphic or pleomorphic adenoma that arises from the salivary glands in the oral cavity. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVOral Cavity Adenoma

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Neoplasm
      - Epithelial neoplasm
        Adenoma
        Oral Cavity Adenoma
        Oral Cavity Monomorphic Adenoma
        Hard Palate Monomorphic Adenoma
        Oral Cavity Pleomorphic Adenoma
        Hard Palate Pleomorphic Adenoma
        Soft Palate Pleomorphic Adenoma

Professional guidelines

PubMed

Pediatric primary salivary gland tumors.

Jesberg P, Monzon A, Gitomer SA, Herrmann BW
Am J Otolaryngol 2023 Sep-Oct;44(5):103948. Epub 2023 Jun 8 doi: 10.1016/j.amjoto.2023.103948. PMID: 37352681

Investigation of Sonographic Criteria for Reliable Identification of T1-T2 Low-Grade Malignant Tumors of the Parotid Gland.

Berner F, Koch M, Müller SK, Schapher M, Grundtner P, Iro H, Mantsopoulos K
Ultrasound Med Biol 2021 Mar;47(3):471-477. Epub 2020 Dec 10 doi: 10.1016/j.ultrasmedbio.2020.11.010. PMID: 33309444

Etiology and management of recurrent parotid pleomorphic adenoma.

Witt RL, Eisele DW, Morton RP, Nicolai P, Poorten VV, Zbären P
Laryngoscope 2015 Apr;125(4):888-93. Epub 2014 Oct 7 doi: 10.1002/lary.24964. PMID: 25289881

See all (52)

Recent clinical studies

Etiology

Updated Salivary Gland Immunohistochemistry: A Review.

Swid MA, Li L, Drahnak EM, Idom H, Quinones W
Arch Pathol Lab Med 2023 Dec 1;147(12):1383-1389. doi: 10.5858/arpa.2022-0461-RA. PMID: 37074867

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Salivary Glands.

Skálová A, Hyrcza MD, Leivo I
Head Neck Pathol 2022 Mar;16(1):40-53. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01420-1. PMID: 35312980 Free PMC Article

Outcomes of drainless outpatient parotidectomy.

Coniglio AJ, Deal AM, Hackman TG
Head Neck 2019 Jul;41(7):2154-2158. Epub 2019 Feb 1 doi: 10.1002/hed.25671. PMID: 30706566

Benign Parotid Tumors.

Zhan KY, Khaja SF, Flack AB, Day TA
Otolaryngol Clin North Am 2016 Apr;49(2):327-42. doi: 10.1016/j.otc.2015.10.005. PMID: 27040584

Giant pleomorphic adenoma of the parotid gland: an unusual case presentation and literature review.

Tarsitano A, Pizzigallo A, Giorgini F, Marchetti C
Acta Otorhinolaryngol Ital 2015 Oct;35(4):293-6. PMID: 26824218 Free PMC Article

See all (796)

Diagnosis

Updated Salivary Gland Immunohistochemistry: A Review.

Swid MA, Li L, Drahnak EM, Idom H, Quinones W
Arch Pathol Lab Med 2023 Dec 1;147(12):1383-1389. doi: 10.5858/arpa.2022-0461-RA. PMID: 37074867

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Salivary Glands.

Skálová A, Hyrcza MD, Leivo I
Head Neck Pathol 2022 Mar;16(1):40-53. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01420-1. PMID: 35312980 Free PMC Article

Pleomorphic adenoma of hard palate: a case report.

Yousra Z, Saliha C
Pan Afr Med J 2021;38:146. Epub 2021 Feb 9 doi: 10.11604/pamj.2021.38.146.26508. PMID: 33912316 Free PMC Article

Sialadenoma Papilliferum.

Hsieh MS, Bishop JA, Yu Fong Chang J
Surg Pathol Clin 2021 Mar;14(1):43-51. Epub 2021 Jan 5 doi: 10.1016/j.path.2020.09.006. PMID: 33526222

Salivary glands.

Silvers AR, Som PM
Radiol Clin North Am 1998 Sep;36(5):941-66, vi. doi: 10.1016/s0033-8389(05)70070-1. PMID: 9747195

See all (1129)

Therapy

Gustatory Hyperhidrosis after Parotid Surgery.

Huang TR, Lee JC
N Engl J Med 2024 Sep 12;391(10):e21. Epub 2024 Sep 7 doi: 10.1056/NEJMicm2404232. PMID: 39248341

Alternative Clinical Indications of Botulinum Toxin.

Alster TS, Harrison IS
Am J Clin Dermatol 2020 Dec;21(6):855-880. doi: 10.1007/s40257-020-00532-0. PMID: 32651806

Functional superficial parotidectomy.

Zhao K, Qi DY, Wang LM
J Oral Maxillofac Surg 1994 Oct;52(10):1038-41. PMID: 8089788

Local capsular dissection of parotid pleomorphic adenomas.

Dallera P, Marchetti C, Campobassi A
Int J Oral Maxillofac Surg 1993 Jun;22(3):154-7. doi: 10.1016/s0901-5027(05)80241-3. PMID: 8393467

Potential for chemoprevention.

DeCosse JJ
Cancer 1982 Dec 1;50(11 Suppl):2550-3. PMID: 7139549

See all (141)

Prognosis

A distinct Fusobacterium nucleatum clade dominates the colorectal cancer niche.

Zepeda-Rivera M, Minot SS, Bouzek H, Wu H, Blanco-Míguez A, Manghi P, Jones DS, LaCourse KD, Wu Y, McMahon EF, Park SN, Lim YK, Kempchinsky AG, Willis AD, Cotton SL, Yost SC, Sicinska E, Kook JK, Dewhirst FE, Segata N, Bullman S, Johnston CD
Nature 2024 Apr;628(8007):424-432. Epub 2024 Mar 20 doi: 10.1038/s41586-024-07182-w. PMID: 38509359 Free PMC Article

Clinicopathological profile of sclerosing polycystic adenoma/adenosis: A systematic review.

de Carvalho Kimura T, de Lima-Souza RA, Scarini JF, Lavareze L, Egal ESA, Altemani A, Mariano FV
Head Neck 2023 Sep;45(9):2449-2457. Epub 2023 Jul 5 doi: 10.1002/hed.27435. PMID: 37403748

Sialadenoma Papilliferum.

Hsieh MS, Bishop JA, Yu Fong Chang J
Surg Pathol Clin 2021 Mar;14(1):43-51. Epub 2021 Jan 5 doi: 10.1016/j.path.2020.09.006. PMID: 33526222

Salivary duct carcinoma.

D'heygere E, Meulemans J, Vander Poorten V
Curr Opin Otolaryngol Head Neck Surg 2018 Apr;26(2):142-151. doi: 10.1097/MOO.0000000000000436. PMID: 29373327

Salivary Gland Tumors: Current Concepts and Controversies.

Seethala RR
Surg Pathol Clin 2017 Mar;10(1):155-176. doi: 10.1016/j.path.2016.11.004. PMID: 28153132

See all (483)

Clinical prediction guides

The intraoral growth patterns of parapharyngeal tumors: A proposed classification system.

Feng Y, Wang J, Li X, Meng L, Rao Y, Yang F
Ear Nose Throat J 2023 Apr;102(4):251-258. Epub 2021 Mar 9 doi: 10.1177/0145561321997557. PMID: 33685250

A rare ectopic localization of pleomorphic adenoma.

Ejeil AL, Moreau N, Le Pelletier F
J Stomatol Oral Maxillofac Surg 2019 Sep;120(4):373-374. Epub 2018 Dec 1 doi: 10.1016/j.jormas.2018.11.016. PMID: 30513390

Salivary duct carcinoma.

D'heygere E, Meulemans J, Vander Poorten V
Curr Opin Otolaryngol Head Neck Surg 2018 Apr;26(2):142-151. doi: 10.1097/MOO.0000000000000436. PMID: 29373327

Lipoadenoma of the Submandibular Gland.

Çelik M, Doruk C, Bayram A, Yegen G, Orhan KS
J Craniofac Surg 2017 Oct;28(7):e680-e682. doi: 10.1097/SCS.0000000000003831. PMID: 28857994

Oral and maxillofacial manifestations of familial adenomatous polyposis.

Wijn MA, Keller JJ, Giardiello FM, Brand HS
Oral Dis 2007 Jul;13(4):360-5. doi: 10.1111/j.1601-0825.2006.01293.x. PMID: 17577321

See all (411)

Recent systematic reviews

Clinicopathological profile of sclerosing polycystic adenoma/adenosis: A systematic review.

de Carvalho Kimura T, de Lima-Souza RA, Scarini JF, Lavareze L, Egal ESA, Altemani A, Mariano FV
Head Neck 2023 Sep;45(9):2449-2457. Epub 2023 Jul 5 doi: 10.1002/hed.27435. PMID: 37403748

Systematic review of prognostic factors in carcinoma ex pleomorphic adenoma.

Key S, Chia C, Hasan Z, Sundaresan P, Dwivedi RC, Riffat F
Oral Oncol 2022 Oct;133:106052. Epub 2022 Jul 31 doi: 10.1016/j.oraloncology.2022.106052. PMID: 35921695

Parotid incidentalomas: a systematic review.

Thompson C, Nolli T, Bannister M
J Laryngol Otol 2021 Sep;135(9):765-769. Epub 2021 Jul 26 doi: 10.1017/S0022215121002036. PMID: 34308809

Benign parotid mass and facial palsy: systematic review.

Stewart KE, Bannon R, Bannister M
Ann R Coll Surg Engl 2021 Jan;103(1):47-52. Epub 2020 Sep 24 doi: 10.1308/rcsann.2020.0194. PMID: 32969265 Free PMC Article

Oral manifestations in patients with familial adenomatous polyposis: A systematic review and meta-analysis.

Almeida FT, Pachêco-Pereira C, Porporatti AL, Flores-Mir C, Leite AF, De Luca Canto G, Guerra EN
J Gastroenterol Hepatol 2016 Mar;31(3):527-40. doi: 10.1111/jgh.13149. PMID: 26331960

See all (15)

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