U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Benign Apocrine Neoplasm

MedGen UID:
272352
•Concept ID:
C1332473
•
Neoplastic Process
Synonyms: Benign Apocrine Neoplasm of Skin; Benign Apocrine Neoplasm of the Skin; Benign Apocrine Skin Neoplasm; Benign Apocrine Skin Tumor; Benign Apocrine Tumor; Benign Apocrine Tumor of Skin; Benign Apocrine Tumor of the Skin

Definition

An epithelial neoplasm that arises from the apocrine glands and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Apocrine Neoplasm

Professional guidelines

PubMed

Current Management and Treatment of Extramammary Paget's Disease.
Hashimoto H, Ito T
Curr Treat Options Oncol 2022 Jun;23(6):818-830. Epub 2022 Apr 4 doi: 10.1007/s11864-021-00923-3. PMID: 35377101
Management of Benign Salivary Gland Conditions.
Bolk K, Mueller K, Phalke N, Walvekar RR
Surg Clin North Am 2022 Apr;102(2):209-231. Epub 2022 Mar 8 doi: 10.1016/j.suc.2022.01.001. PMID: 35344693
Management of Mucoceles, Sialoceles, and Ranulas.
Bowers EMR, Schaitkin B
Otolaryngol Clin North Am 2021 Jun;54(3):543-551. doi: 10.1016/j.otc.2021.03.002. PMID: 34024482

Recent clinical studies

Etiology

Extracapsular dissection via single cervical incision for parotid pleomorphic adenoma.
Roh JL
Clin Oral Investig 2023 Dec 28;28(1):40. doi: 10.1007/s00784-023-05420-5. PMID: 38151592
Updated Salivary Gland Immunohistochemistry: A Review.
Swid MA, Li L, Drahnak EM, Idom H, Quinones W
Arch Pathol Lab Med 2023 Dec 1;147(12):1383-1389. doi: 10.5858/arpa.2022-0461-RA. PMID: 37074867
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Salivary Glands.
Skálová A, Hyrcza MD, Leivo I
Head Neck Pathol 2022 Mar;16(1):40-53. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01420-1. PMID: 35312980Free PMC Article
An update on extracapsular dissection for the management of parotid gland pleomorphic adenoma.
Loke WL, Rahimi S, Brennan PA
J Oral Pathol Med 2022 Mar;51(3):219-222. Epub 2021 Oct 25 doi: 10.1111/jop.13251. PMID: 34697837
Benign Parotid Tumors.
Zhan KY, Khaja SF, Flack AB, Day TA
Otolaryngol Clin North Am 2016 Apr;49(2):327-42. doi: 10.1016/j.otc.2015.10.005. PMID: 27040584

Diagnosis

Leiomyoma of submandibular gland.
Ukwas A, Elshikh M, Umar T, Borumandi F
BMJ Case Rep 2024 Jul 16;17(7) doi: 10.1136/bcr-2023-258871. PMID: 39013622
Pitfalls in Prostate MR Imaging Interpretation.
Sudha Surasi DS, Kalva P, Hwang KP, Bathala TK
Radiol Clin North Am 2024 Jan;62(1):53-67. Epub 2023 Aug 21 doi: 10.1016/j.rcl.2023.07.001. PMID: 37973245
Imaging of Major Salivary Gland Lesions and Disease.
Friedman E, Cai Y, Chen B
Oral Maxillofac Surg Clin North Am 2023 Aug;35(3):435-449. Epub 2023 Apr 7 doi: 10.1016/j.coms.2023.02.007. PMID: 37032181
Benign Parotid Tumors.
Zhan KY, Khaja SF, Flack AB, Day TA
Otolaryngol Clin North Am 2016 Apr;49(2):327-42. doi: 10.1016/j.otc.2015.10.005. PMID: 27040584
Eccrine angiomatous hamartoma.
Dadlani C, Orlow SJ
Dermatol Online J 2006 Sep 8;12(5):9. PMID: 16962024

Therapy

The spread of retzius-sparing robotic prostatectomy: an update after 10 years.
Galfano A, Secco S, Olivero A, Bocciardi AM, Dell'Oglio P
Curr Opin Urol 2023 Sep 1;33(5):367-374. Epub 2023 Jun 21 doi: 10.1097/MOU.0000000000001112. PMID: 37345338
Conservative interventions for managing urinary incontinence after prostate surgery.
Johnson EE, Mamoulakis C, Stoniute A, Omar MI, Sinha S
Cochrane Database Syst Rev 2023 Apr 18;4(4):CD014799. doi: 10.1002/14651858.CD014799.pub2. PMID: 37070660Free PMC Article
Keratocystoma of the parotid gland.
Komatsu H, Kumoi K, Inokuchi G, Hashimoto K, Nagao T, Otsuki N, Nibu KI
Auris Nasus Larynx 2020 Jun;47(3):481-484. Epub 2019 Jun 21 doi: 10.1016/j.anl.2019.05.006. PMID: 31230813
Testosterone Deficiency and the Prostate.
Alukal JP, Lepor H
Urol Clin North Am 2016 May;43(2):203-8. doi: 10.1016/j.ucl.2016.01.013. PMID: 27132577
Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets.
Beltran H, Rickman DS, Park K, Chae SS, Sboner A, MacDonald TY, Wang Y, Sheikh KL, Terry S, Tagawa ST, Dhir R, Nelson JB, de la Taille A, Allory Y, Gerstein MB, Perner S, Pienta KJ, Chinnaiyan AM, Wang Y, Collins CC, Gleave ME, Demichelis F, Nanus DM, Rubin MA
Cancer Discov 2011 Nov;1(6):487-95. doi: 10.1158/2159-8290.CD-11-0130. PMID: 22389870Free PMC Article

Prognosis

Evaluation: Imaging Studies.
Kontzialis M, Glastonbury CM, Aygun N
Adv Otorhinolaryngol 2016;78:25-38. Epub 2016 Apr 12 doi: 10.1159/000442122. PMID: 27093072
Major and minor salivary gland tumors.
Guzzo M, Locati LD, Prott FJ, Gatta G, McGurk M, Licitra L
Crit Rev Oncol Hematol 2010 May;74(2):134-48. Epub 2009 Nov 24 doi: 10.1016/j.critrevonc.2009.10.004. PMID: 19939701
Eccrine angiomatous hamartoma.
Dadlani C, Orlow SJ
Dermatol Online J 2006 Sep 8;12(5):9. PMID: 16962024
Sialadenoma papilliferum.
Cleary KR, Batsakis JG
Ann Otol Rhinol Laryngol 1990 Sep;99(9 Pt 1):756-8. doi: 10.1177/000348949009900918. PMID: 2396815
Organoid nevus.
Pinkus H
Mod Probl Paediatr 1976 Oct 20-23;20:50-7. PMID: 1032522

Clinical prediction guides

Uncommon case of cytopathological features of sialadenoma papilliferum.
Oyama Y, Nishida H, Kondo Y, Kusaba T, Kawamura K, Fujimoto A, Yokomine Y, Kiyooka S, Iwao S, Hirakawa K, Kawano K, Daa T
Diagn Cytopathol 2023 Jul;51(7):E224-E227. Epub 2023 Apr 13 doi: 10.1002/dc.25139. PMID: 37052154
A rare ectopic localization of pleomorphic adenoma.
Ejeil AL, Moreau N, Le Pelletier F
J Stomatol Oral Maxillofac Surg 2019 Sep;120(4):373-374. Epub 2018 Dec 1 doi: 10.1016/j.jormas.2018.11.016. PMID: 30513390
Lipoadenoma of the Submandibular Gland.
Çelik M, Doruk C, Bayram A, Yegen G, Orhan KS
J Craniofac Surg 2017 Oct;28(7):e680-e682. doi: 10.1097/SCS.0000000000003831. PMID: 28857994
Evaluation: Imaging Studies.
Kontzialis M, Glastonbury CM, Aygun N
Adv Otorhinolaryngol 2016;78:25-38. Epub 2016 Apr 12 doi: 10.1159/000442122. PMID: 27093072
Organoid nevus.
Pinkus H
Mod Probl Paediatr 1976 Oct 20-23;20:50-7. PMID: 1032522

Recent systematic reviews

Clinicopathological profile of sclerosing polycystic adenoma/adenosis: A systematic review.
de Carvalho Kimura T, de Lima-Souza RA, Scarini JF, Lavareze L, Egal ESA, Altemani A, Mariano FV
Head Neck 2023 Sep;45(9):2449-2457. Epub 2023 Jul 5 doi: 10.1002/hed.27435. PMID: 37403748
Enucleation of the prostate as retreatment for recurrent or residual benign prostatic obstruction: a systematic review and a meta-analysis.
Pyrgidis N, Mykoniatis I, Lusuardi L, Schulz GB, Sokolakis I, Stief C, Sountoulides P
Prostate Cancer Prostatic Dis 2023 Dec;26(4):693-701. Epub 2023 May 16 doi: 10.1038/s41391-023-00677-z. PMID: 37193777
A systematic review and meta-analysis of artificial intelligence diagnostic accuracy in prostate cancer histology identification and grading.
Morozov A, Taratkin M, Bazarkin A, Rivas JG, Puliatti S, Checcucci E, Belenchon IR, Kowalewski KF, Shpikina A, Singla N, Teoh JYC, Kozlov V, Rodler S, Piazza P, Fajkovic H, Yakimov M, Abreu AL, Cacciamani GE, Enikeev D; Young Academic Urologists (YAU) Working Group in Uro-technology of the European Association of Urology
Prostate Cancer Prostatic Dis 2023 Dec;26(4):681-692. Epub 2023 Apr 25 doi: 10.1038/s41391-023-00673-3. PMID: 37185992
Conservative interventions for managing urinary incontinence after prostate surgery.
Johnson EE, Mamoulakis C, Stoniute A, Omar MI, Sinha S
Cochrane Database Syst Rev 2023 Apr 18;4(4):CD014799. doi: 10.1002/14651858.CD014799.pub2. PMID: 37070660Free PMC Article
Dermoscopy of cutaneous adnexal tumours: a systematic review of the literature.
Lai M, Muscianese M, Piana S, Chester J, Borsari S, Paolino G, Pellacani G, Longo C, Pampena R
J Eur Acad Dermatol Venereol 2022 Sep;36(9):1524-1540. Epub 2022 May 25 doi: 10.1111/jdv.18210. PMID: 35536546Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...