Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Childhood testicular neoplasm

MedGen UID:: 272472
•Concept ID:: C1333010
•: Neoplastic Process

Synonyms:	Childhood Neoplasm of Testis; childhood neoplasm of testis; Childhood Neoplasm of the Testis; childhood neoplasm of the testis; Childhood Testicular Neoplasm; childhood testicular neoplasm; neoplasm of testis of childhood; paediatric neoplasm of testis; paediatric neoplasm of the testis; paediatric testicular neoplasm; Pediatric Neoplasm of Testis; pediatric neoplasm of testis; Pediatric Neoplasm of the Testis; pediatric neoplasm of the testis; Pediatric Testicular Neoplasm; pediatric testicular neoplasm; Testicular Tumor, Childhood; testicular tumor, childhood

Monarch Initiative:	MONDO:0037250

Definition

A neoplasm that affects the testis during childhood. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVChildhood testicular neoplasm

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Neoplasm
      - Neoplasm by Special Category
        Childhood neoplasm
        Childhood testicular neoplasm
        Childhood testicular germ cell tumor
        Childhood Malignant Testicular Germ Cell Tumor
        Childhood embryonal testis carcinoma
        Childhood testicular choriocarcinoma
        Childhood testicular mixed germ cell cancer
        Childhood Testicular Yolk Sac Tumor
        Childhood Testicular Non-Seminomatous Germ Cell Tumor
        Childhood testicular mixed embryonal carcinoma and teratoma
        Childhood Testicular Teratoma

Professional guidelines

PubMed

Different Clinical Presentations and Management in Complete Androgen Insensitivity Syndrome (CAIS).

Lanciotti L, Cofini M, Leonardi A, Bertozzi M, Penta L, Esposito S
Int J Environ Res Public Health 2019 Apr 9;16(7) doi: 10.3390/ijerph16071268. PMID: 30970592 Free PMC Article

Testicular function after cancer treatment in childhood.

Jahnukainen K, Söder O
Endocr Dev 2003;5:124-35. doi: 10.1159/000069293. PMID: 12629896

Role of the surgeon in the treatment of children's cancer.

Leonard AS, Alyono D, Fischel RJ, Nesbit ME, Nguyen DH, McClain KL
Surg Clin North Am 1985 Dec;65(6):1387-422. doi: 10.1016/s0039-6109(16)43780-1. PMID: 3000008

See all (39)

Recent clinical studies

Etiology

What should be done in terms of fertility preservation for patients with cancer? The French 2021 guidelines.

Rives N, Courbière B, Almont T, Kassab D, Berger C, Grynberg M, Papaxanthos A, Decanter C, Elefant E, Dhedin N, Barraud-Lange V, Béranger MC, Demoor-Goldschmidt C, Frédérique N, Bergère M, Gabrel L, Duperray M, Vermel C, Hoog-Labouret N, Pibarot M, Provansal M, Quéro L, Lejeune H, Methorst C, Saias J, Véronique-Baudin J, Giscard d'Estaing S, Farsi F, Poirot C, Huyghe É
Eur J Cancer 2022 Sep;173:146-166. Epub 2022 Aug 3 doi: 10.1016/j.ejca.2022.05.013. PMID: 35932626

DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies.

Schultz KAP, Williams GM, Kamihara J, Stewart DR, Harris AK, Bauer AJ, Turner J, Shah R, Schneider K, Schneider KW, Carr AG, Harney LA, Baldinger S, Frazier AL, Orbach D, Schneider DT, Malkin D, Dehner LP, Messinger YH, Hill DA
Clin Cancer Res 2018 May 15;24(10):2251-2261. Epub 2018 Jan 17 doi: 10.1158/1078-0432.CCR-17-3089. PMID: 29343557 Free PMC Article

Therapy-related myeloid neoplasms.

Leone G, Fianchi L, Voso MT
Curr Opin Oncol 2011 Nov;23(6):672-80. doi: 10.1097/CCO.0b013e32834bcc2a. PMID: 21918440

Acute lymphoblastic leukemia in childhood.

Poplack DG
Pediatr Clin North Am 1985 Jun;32(3):669-97. doi: 10.1016/s0031-3955(16)34831-3. PMID: 3889802

The success and failure of multimodal therapy for cancer in children.

Evans AE
Cancer 1975 Jan;35(1):48-54. doi: 10.1002/1097-0142(197501)35:1<48::aid-cncr2820350107>3.0.co;2-b. PMID: 162853

See all (385)

Diagnosis

DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies.

Cryptorchidism. Current concepts.

Gill B, Kogan S
Pediatr Clin North Am 1997 Oct;44(5):1211-27. doi: 10.1016/s0031-3955(05)70554-x. PMID: 9326959

Management of teratoma.

Herr HW, LaQuaglia MP
Urol Clin North Am 1993 Feb;20(1):145-52. PMID: 8434433

Endocrine disorders in children.

Chernausek SD, Leslie ND, Bloch CA, Sperling MA
Surg Clin North Am 1985 Dec;65(6):1527-49. doi: 10.1016/s0039-6109(16)43785-0. PMID: 2866586

Paratesticular rhabdomyosarcoma in childhood.

Raney RB Jr, Hays DM, Lawrence W Jr, Soule EH, Tefft M, Donaldson MH
Cancer 1978 Aug;42(2):729-36. doi: 10.1002/1097-0142(197808)42:2<729::aid-cncr2820420246>3.0.co;2-r. PMID: 354776

See all (311)

Therapy

Evolutionary determinants of curability in cancer.

Mansur MB, deSouza NM, Natrajan R, Abegglen LM, Schiffman JD, Greaves M
Nat Ecol Evol 2023 Nov;7(11):1761-1770. Epub 2023 Aug 24 doi: 10.1038/s41559-023-02159-w. PMID: 37620552

Cryptorchidism. Current concepts.

Gill B, Kogan S
Pediatr Clin North Am 1997 Oct;44(5):1211-27. doi: 10.1016/s0031-3955(05)70554-x. PMID: 9326959

Neurofibromatosis and malignancy.

Warrier RP, Kini KR, Raju U, Shumacher B, Wu K
Clin Pediatr (Phila) 1985 Oct;24(10):584-5. doi: 10.1177/000992288502401007. PMID: 2992863

Acute lymphoblastic leukemia.

Miller DR
Pediatr Clin North Am 1980 May;27(2):269-91. doi: 10.1016/s0031-3955(16)33851-2. PMID: 6992074

Paratesticular rhabdomyosarcoma in childhood.

Raney RB Jr, Hays DM, Lawrence W Jr, Soule EH, Tefft M, Donaldson MH
Cancer 1978 Aug;42(2):729-36. doi: 10.1002/1097-0142(197808)42:2<729::aid-cncr2820420246>3.0.co;2-r. PMID: 354776

See all (215)

Prognosis

Management of teratoma.

Herr HW, LaQuaglia MP
Urol Clin North Am 1993 Feb;20(1):145-52. PMID: 8434433

Acute lymphoblastic leukemia in childhood.

Poplack DG
Pediatr Clin North Am 1985 Jun;32(3):669-97. doi: 10.1016/s0031-3955(16)34831-3. PMID: 3889802

Acute lymphoblastic leukemia.

Miller DR
Pediatr Clin North Am 1980 May;27(2):269-91. doi: 10.1016/s0031-3955(16)33851-2. PMID: 6992074

Paratesticular rhabdomyosarcoma in childhood.

Raney RB Jr, Hays DM, Lawrence W Jr, Soule EH, Tefft M, Donaldson MH
Cancer 1978 Aug;42(2):729-36. doi: 10.1002/1097-0142(197808)42:2<729::aid-cncr2820420246>3.0.co;2-r. PMID: 354776

The success and failure of multimodal therapy for cancer in children.

Evans AE
Cancer 1975 Jan;35(1):48-54. doi: 10.1002/1097-0142(197501)35:1<48::aid-cncr2820350107>3.0.co;2-b. PMID: 162853

See all (246)

Clinical prediction guides

Hormonal control during infancy and testicular adrenal rest tumor development in males with congenital adrenal hyperplasia: a retrospective multicenter cohort study.

Schröder MAM, Neacşu M, Adriaansen BPH, Sweep FCGJ, Ahmed SF, Ali SR, Bachega TASS, Baronio F, Birkebæk NH, de Bruin C, Bonfig W, Bryce J, Clemente M, Cools M, Elsedfy H, Globa E, Guran T, Güven A, Amr NH, Janus D, Taube NL, Markosyan R, Miranda M, Poyrazoğlu Ş, Rees A, Salerno M, Stancampiano MR, Vieites A, de Vries L, Yavas Abali Z, Span PN, Claahsen-van der Grinten HL
Eur J Endocrinol 2023 Oct 17;189(4):460-468. doi: 10.1093/ejendo/lvad143. PMID: 37837609

The systematic analysis and 10-year prediction on disease burden of childhood cancer in China.

Zhu B, Wu X, An W, Yao B, Liu Y
Front Public Health 2022;10:908955. Epub 2022 Sep 6 doi: 10.3389/fpubh.2022.908955. PMID: 36148350 Free PMC Article

Endocrine disruptors and the male reproductive system.

Stukenborg JB, Mitchell RT, Söder O
Best Pract Res Clin Endocrinol Metab 2021 Sep;35(5):101567. Epub 2021 Aug 14 doi: 10.1016/j.beem.2021.101567. PMID: 34426080

Therapy-related myeloid neoplasms.

Leone G, Fianchi L, Voso MT
Curr Opin Oncol 2011 Nov;23(6):672-80. doi: 10.1097/CCO.0b013e32834bcc2a. PMID: 21918440

Isolated extramedullary relapse in childhood acute lymphocytic leukemia.

Jacobs JE, Hastings C
Curr Hematol Malig Rep 2010 Oct;5(4):185-91. doi: 10.1007/s11899-010-0063-9. PMID: 20717757

See all (148)

Recent systematic reviews

The impact of vincristine on testicular development and function in childhood cancer.

Clark I, Brougham MFH, Spears N, Mitchell RT
Hum Reprod Update 2023 Mar 1;29(2):233-245. doi: 10.1093/humupd/dmac039. PMID: 36495566 Free PMC Article

Giant prolactinoma in children and adolescents: a single-center experience and systematic review.

Kumar S, Sarathi V, Lila AR, Sehemby M, Memon SS, Karlekar M, Sankhe S, Patil VA, Shah N, Bandgar T
Pituitary 2022 Dec;25(6):819-830. Epub 2022 Jul 18 doi: 10.1007/s11102-022-01250-y. PMID: 35851929

The prognostic value of testicular microlithiasis as an incidental finding for the risk of testicular malignancy in children and the adult population: A systematic review. On behalf of the EAU pediatric urology guidelines panel.

't Hoen LA, Bhatt NR, Radmayr C, Dogan HS, Nijman RJM, Quaedackers J, Rawashdeh YF, Silay MS, Tekgul S, Stein R, Bogaert G
J Pediatr Urol 2021 Dec;17(6):815-831. Epub 2021 Jun 13 doi: 10.1016/j.jpurol.2021.06.013. PMID: 34217588

Physical activity and risk of testicular cancer: a systematic review.

Huang S, Signal V, Sarfati D, Shaw C, Stanley J, McGlynn K, Gurney J
BMC Cancer 2018 Feb 14;18(1):189. doi: 10.1186/s12885-018-4093-3. PMID: 29444652 Free PMC Article

Fertility Preservation in Children and Adolescents With Cancer.

Long CJ, Ginsberg JP, Kolon TF
Urology 2016 May;91:190-6. Epub 2016 Jan 11 doi: 10.1016/j.urology.2015.10.047. PMID: 26790587

See all (10)

MedGen

National Center for Biotechnology Information

Send to:

Childhood testicular neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

Related information

Recent activity